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Z

Zichao Yang

southern medical university
H指数:18
被引数:838

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Identification of flupirtine as a candidate against liver fibrosis in mice: Preserving mitochondria quality by suppressing calpain 1/complex I/mtROS axis via targeting asparagine synthase

通过靶向天冬酰胺合酶抑制钙蛋白酶1/复合物I/mtROS轴来保护线粒体质量，将氟吡汀鉴定为小鼠抗肝纤维化的候选药物

Acta Pharmaceutica Sinica B
IF14.6
2026-08-210
OAAI
Yong Rao; Rui Su; Hui-ling Fu; Jin Liu; Wen-jie Cao; Zichao Yang; Chen Zhang; Xiaoxuan Su; Feifei Liu; Zhong-ping Jiang; Congjun Xu; Wandi Xiong; Haibin Luo; Ling Huang
Novel 2-amino-4-(1H-imidazol)pyridine derivatives as potent brain-penetrant EGFR mutant inhibitors: Design, synthesis, biological evaluation, and molecular modeling study

新型2-氨基-4-(1H-咪唑)吡啶衍生物作为强效脑穿透性EGFR突变体抑制剂：设计、合成、生物评价及分子模拟研究

Bioorganic Chemistry
IF4.7
2026-08-010
PRE
Zhang, Tingting; Peng, Shunli; Huang, Yaqi; Huang, Chunhui; Yang, Zichao; Chen, Yongxin; Jiang, Ying; Liu, Siming; Wan, Shanhe; Yang, Haikui; Zhang, Jiajie
Discovery of novel 3-Benzyloxyaminopyridines as orally available and intracranially active selective ROS1 inhibitors for combating the resistant ROS1G2032R mutation

新型3-苄氧氨基吡啶类化合物的发现：作为口服可利用且具有颅内活性的选择性ROS1抑制剂，用于对抗耐药的ROS1G2032R突变

European Journal of Medicinal Chemistry
IF5.9
2025-08-260
PRE
Siming Liu; Yuanxin Tian; Yaqi Huang; Yong Lin; Guowu Wu; Zichao Yang; Fengqiu Guo; Yongxin Chen; Chunhui Huang; Ying Jiang; Chuan Huang; Zhonghuang Li; Shanhe Wan; Xiaoyun Wu; Jiajie Zhang

研究方向

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J
Jianjun Chen
H 指数:45论文数:189被引数:6,274
T
Tingting Zhang
H 指数:29论文数:161被引数:3,030
J
Jiajie Zhang
H 指数:34论文数:183被引数:4,528
Z
Zhonghuang Li
H 指数:16论文数:56被引数:596
Y
Ying Jiang
H 指数:40论文数:147被引数:6,973
L
Lishun Zhang
H 指数:3论文数:6被引数:31
X
Xiaopeng Peng
H 指数:18论文数:84被引数:1,092
C
Chunhui Huang
H 指数:22论文数:70被引数:3,463
陈婷 封面图
陈婷
H 指数:38论文数:197被引数:3,821
黄俊丽 封面图
黄俊丽
H 指数:37论文数:235被引数:5,460