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S

Serdar Durdağı

Bahçeşehir University

41H指数
329论文数
5.3K被引数
收录论文 118
发表时间
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JAK2-driven hERG trafficking reprograms bioelectric states to promote retinoblastoma invasionJAK2驱动的hERG转运重编程生物电状态以促进视网膜母细胞瘤侵袭
errCell Death & Disease
IF9.6
err2026-10-02
err0
errOAAI
errSerdar Durdağı; Pragati Gupta; Yagmur Demircan-Yalcin; Basma Sukkar; Ismail Erol; Alper Devrim Özkan; Shefalee K. Bhavsar; Berna Dogan; Dennis-Dominik Rosmus; Julian Wolf; Tatsiana Castor; Ayse Sahaboglu; Yogesh Singh; Clemens Lange; Peter Wieghofer; Zohreh Hosseinzadeh
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Hot spot-driven discovery of β-catenin/Tcf4 interaction inhibitors via virtual drug repurposing study and experimental validation in colorectal cancer cells热点驱动的β-连环蛋白/Tcf4相互作用抑制剂发现：通过虚拟药物重定位研究和结直肠癌细胞实验验证
errMolecular Diversity
IF3.8
err2026-09-09
err0
PREAI
errKader Sahin; Ajda Coker; Serdar Durdağı
err分享
err收藏
Machine-learning–guided library screening and drug resistance profiling of HIV-1 protease inhibitors机器学习指导的HIV-1蛋白酶抑制剂的库筛选和药物抗性分析
errJOURNAL OF MOLECULAR GRAPHICS & MODELLING
IF3
err2026-08-08
err0
PREAI
errHuseyin Tunc; Sumeyye Yilmaz; Ehsan Sayyah; Serdar Durdaǧi
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err收藏
Development of Dynamic Structure-Based Pharmacophore Models to Target OX40-OX40L Interaction With Potential Small Molecule Therapeutics: Targeting Tumor Microenvironment基于动态结构构建靶向OX40-OX40L相互作用的药物模型：靶向肿瘤微环境的潜在小分子治疗剂
errChemistrySelect
IF2
err2026-05-08
err0
PREAI
errIkram, Saima; Sayyah, Ehsan; Oktay, Lalehan; Ulug, Muhammet Eren; Durdagi, Serdar
err分享
err收藏
Novel 1,2,3-Thiadiazole-based Hydrazone and 1,3,4-Oxadiazole hybrids as promising agents against Streptococcus mutans: Synthesis, biological evaluation, and molecular modeling studies新型1,2,3-噻二唑基 hydrazone 和 1,3,4-噁二唑杂化物作为抗变异链球菌的潜在药物：合成、生物评价及分子模拟研究
errBioorganic Chemistry
IF4.7
err2026-04-30
err0
PREAI
errİlayda Gül Kurtuluş; Hatice Başpinar Küçük; Sümeyye Elif Kahya; Ayşe Esra Karadağ; Salma Ghazy; Serdar Durdaği
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Advancing Accurate Quantification of Protein-Ligand Interactions: Differential Scanning Calorimetry as a Precision Screening Tool Using BCL-2 as a Model System推进蛋白-配体相互作用的精确量化：以BCL-2为模型系统，将差示扫描量热法用作精密筛选工具
errChemMedChem
IF3.4
err2026-03-03
err0
PREAI
errBircan Dinc; Berna Dogan; Thomas Mavromoustakos; Serdar Durdağı
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New diclofenac hydrazones: Design, synthesis, in silico studies and anticancer evaluation against breast cancer新型双氯芬酸腙衍生物：设计、合成、计算机模拟研究及对乳腺癌的抗癌活性评价
errJournal of Molecular Structure
IF4.7
err2025-11-14
err0
PREAI
errKaan Birgül; Lalehan Oktay; Hatice Bekci; Pelin Çıkla-Süzgün; Serdar Durdağı; Ş. Güniz Küçükgüzel
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Targeting Ubiquitin-Specific Protease 7 (USP7): A Pharmacophore-Guided Drug Repurposing and Physics-Based Molecular Simulation Study靶向泛素特异性蛋白酶7 (USP7)：一项基于药效团的药物重定位和基于物理的分子模拟研究
errACS Omega
IF4.3
err2025-10-20
err0
errOAAI
errDuaa Kanan; Tarek Kanan; Berna Dogan; Ismail Erol; Serdar Durdağı
err分享
err收藏
A Novel Multi-Tiered Hybrid Virtual Screening Pipeline for the Discovery of WDR5-MLL1 Interaction Disruptors in Precision Cancer Therapy一种用于精准癌症治疗中WDR5-MLL1相互作用破坏剂发现的新型多层级混合虚拟筛选流程
errACS OMEGA
IF4.3
err2025-09-01
err0
PREAI
errAbuelrub, Anwar; Erol, Ismail; Durdagi, Serdar
err分享
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Anti-cancer efficacy of novel lonidamine derivatives: Design, synthesis, in vitro, in vivo, and computational studies targeting hexokinase-2新型棉酚衍生物的抗肿瘤活性：设计、合成、体外、体内及针对己糖激酶-2的计算研究
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-06-19
err0
PREAI
errӦzgecan Şavluğ İpek; Bilgesu Onur Sucu; Saba Selvi; Fulya Koksalar Alkan; Büşra Tiryaki; Hilmi Kaan Alkan; Ehsan Sayyah; İlayda Tolu; Mustafa Güzel; Serdar Durdağı; Nuri Öztürk; Hasan Korkaya
err分享
err收藏
Beyond Docking: A Multitier Computational Pipeline for USP7 Inhibitor Optimization超越对接：一种用于USP7抑制剂优化的多层级计算流水线
errChemMedChem
IF3.4
err2025-06-16
err0
PREAI
errEhsan Sayyah; Muhammet Eren Ulug; Serdar Durdağı
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err收藏
Employing steered MD simulations for effective virtual screening: Active pharmacophore search by dynamic corrections to target MKK3-MYC interactions采用引导分子动力学模拟进行有效的虚拟筛选：通过动态校正主动药效团搜索以靶向MKK3-MYC相互作用
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2025-05-01
err0
errOAAI
errUlug, Muhammet Eren; Ikram, Saima; Sayyah, Ehsan; Durdagi, Serdar
err分享
err收藏
Computational Analysis of CC2D1A Missense Mutations: Insight into Protein Structure and Interaction Dynamics
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2025-01-10
err0
errOAAI
errAbuelrub, Anwar; Erol, Ismail; Bingol, Nurdeniz Nalbant; Sag, Sebnem Ozemri; Temel, Sehime G.; Durdagi, Serdar
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Synthesis, in silico and bio-evaluation studies of new isothiocyanate derivatives with respect to COX inhibition and H2S release profiles
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errYilmaz, Yakup Berkay; Guengoer, Tugba; Doenmez, Serhat; Atalay, Hazal Nazlican; Siyah, Pinar; Durdagi, Serdar; Ay, Mehmet; Boyunegmez Tumer, Tugba
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Imidazole-based hydrazones as potent anti-colon cancer agents: Design, synthesis, biological evaluation and computational studies
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-12-01
err1
PREAI
errTapera, Michael; Dogan, Eylul; Sahin, Kader; Gozkamane, Gaye Alara; Kekecmuhammed, Huseyin; Sandal, Semiha; Gurkan, Ajda Coker; Bora, Rifat Emin; Anber, Anber; Durdagi, Serdar; Zorlu, Yunus; Saripinar, Emin
err分享
err收藏
Synthesis of Tryptamine-Thiazolidin-4-one Derivatives and the Combined In Silico and In Vitro Evaluation of their Biological Activity and Cytotoxicity
errACS OMEGA
IF4.3
err2024-10-23
err0
errOAAI
errAydin, Seher; Ergun, Yavuz; Ghazy, Salma; Celebi, Asuman; Kilic, Turker; Avsar, Timucin; Durdagi, Serdar
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Investigating the Effect of GLU283 Protonation State on the Conformational Heterogeneity of CCR5 by Molecular Dynamics Simulations
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-10-22
err1
errOAAI
errDogan, Berna; Durdagi, Serdar
err分享
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Improving Predictive Efficacy for Drug Resistance in Novel HIV-1 Protease Inhibitors through Transfer Learning Mechanisms
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-10-11
err0
PREAI
errTunc, Huseyin; Yilmaz, Sumeyye; Kiraz, Busra Nur Darendeli; Sari, Murat; Kotil, Seyfullah Enes; Sensoy, Ozge; Durdagi, Serdar
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Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment
errSCIENTIFIC REPORTS
IF3.9
err2024-09-28
err1
errOAAI
errAlkan, Fulya Koksalar; Caglayan, Ahmet Burak; Alkan, Hilmi Kaan; Benson, Elayne; Gunduz, Yunus Emre; Sensoy, Ozge; Durdagi, Serdar; Zarbaliyev, Elbrus; Dyson, Greg; Assad, Hadeel; Shull, Austin; Chadli, Ahmed; Shi, Huidong; Ozturk, Gurkan; Korkaya, Hasan
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Are Terminal Alkynes Necessary for MAO-A/MAO-B Inhibition? A New Scaffold Is Revealed
errMOLECULES
IF4.6
err2024-05-24
err1
errOAAI
errMavroeidi, Panagiou; Zorba, Leandros P.; Tzouras, Nikolaos V.; Neofotistos, Stavros P.; Georgiou, Nikitas; Sahin, Kader; Sentuerk, Murat; Durdagi, Serdar; Vougioukalakis, Georgios C.; Mavromoustakos, Thomas
err分享
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研究方向

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合作学者
合作期刊
V
Vladimir N. Uversky
H 指数: 155 · 论文数: 2.5K
C
Claudiu T. Supuran
H 指数: 152 · 论文数: 4.2K
İ
İlhami Gülçın
H 指数: 128 · 论文数: 676
A
Andrea Scozzafava
H 指数: 115 · 论文数: 827
M
Martin J. Lohse
H 指数: 100 · 论文数: 541
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