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D

Dustin Dovala

Novartis
H指数:19
被引数:1,689

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Targeted Transcriptional Repression by Induced Proximity

诱导邻近靶向转录抑制

ACS Central Science
IF10.4
2026-06-110
OAAI
Christian E. Stieger; Xinru Chen; Christina C. Kuismi; Dustin Dovala; Daniel Fuller; Andreas O. Frank; Mikias Woldegiorgis; Megan Bruce-Smythe; Fabian Wu; Nicolas Pizzato; Jeffrey McKenna; Cory Johannessen; Barna D. Fodor; Markus Schirle; Daniel K. Nomura
Discovery of EGT710; an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor

EGT710的发现：一种口服非肽类拟似可逆共价SARS-CoV-2主蛋白酶抑制剂

Journal of Medicinal Chemistry
IF6.8
2026-02-090
PRE
Julien P. N. Papillon; Jun Yuan; Matthew J. Hesse; Lei Zhang; Richard I. Robinson; Nathaniel F. Ware; Viktor Hornak; Rajeshri G. Karki; Tom Kirrane; Keira Garland; Sajan Joseph; Stephanie A. Moquin; Suresh B. Lakshminarayana; Laura Tandeske; Dustin Dovala; Mark Knapp; Elizabeth Ornelas; Daniel Fuller; Pei-i Ho; Xuping Xie; Katarina Vulic; Suzanne M. Skolnik; Jinhai Gao; Mark Zambrowski; Meike Spiess; José S. Duca; Scott A. Busby; Markus Schirle; Michael Robinson; Pei-Yong Shi; Heinz E. Moser; Christopher Sarko; James E. Bradner; Thierry T. Diagana; John A. Tallarico
Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

亚砜基偶氮环丙烷作为致癌转录因子MYC的立体选择性共价失稳降解剂

Angewandte Chemie International Edition
IF0
2025-09-250
PRE
Hannah T. Rosen; Kelvin Li; Christian E. Stieger; Erin L. Li; Brynne Currier; Scott M. Brittain; Francisco J. Garcia; Diana C. Beard; Michael D. Jones; Sandra Haenni-Holzinger; Dustin Dovala; Jeffrey M. McKenna; Markus Schirle; Thomas J. Maimone; Daniel K. Nomura
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1

一种靶向半胱氨酸二氧合酶1的小分子VHL分子胶降解剂

Nature Chemical Biology
IF13.7
2025-06-240
OA
Antonin Tutter; Dennis Buckley; Andrei A. Golosov; Xiaolei Ma; Wei Shu; Daniel J. J. McKay; Veronique Darsigny; Dustin Dovala; Rohan Beckwith; Jonathan Solomon; Pasupuleti Rao; Lei Xu; Aleem Fazal; Andreas Lingel; Charles Wartchow; Jennifer S. Cobb; Amanda Hachey; Jennifer Tullai; Gregory A. Michaud
Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-09-270
OAAI
Barkan, David T.; Garland, Keira; Zhang, Lei; Eastman, Richard T.; Hesse, Matthew; Knapp, Mark; Ornelas, Elizabeth; Tang, Jenny; Cortopassi, Wilian Augusto; Wang, Yu; King, Frederick; Jia, Weiping; Nguyen, Zachary; Frank, Andreas O.; Chan, Ryan; Fang, Eric; Fuller, Daniel; Busby, Scott; Carias, Heidi; Donahue, Kristine; Tandeske, Laura; Diagana, Thierry T.; Jarrousse, Nadine; Moser, Heinz; Sarko, Christopher; Dovala, Dustin; Moquin, Stephanie; Marx, Vanessa M.
Rational Chemical Design of Molecular Glue Degraders

分子胶降解剂的合理化学设计

ACS CENTRAL SCIENCE
IF10.4
2023-04-1158
OAAI
Toriki, Ethan S.; Papatzimas, James W.; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O.; Hesse, Matthew J.; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J.; Brittain, Scott M.; Kile, Andrew C.; McGregor, Lynn M.; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.
An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2022-12-0919
OA
Gonzalez-Valero, Angel; Reeves, Audrey G.; Page, Annika C. S.; Moon, Patrick J.; Miller, Edward; Coulonval, Katia; Crossley, Steven W. M.; Xie, Xiao; He, Dan; Musacchio, Patricia Z.; Christian, Alec H.; McKenna, Jeffrey M.; Lewis, Richard A.; Fang, Eric; Dovala, Dustin; Lu, Yipin; McGregor, Lynn M.; Schirle, Markus; Tallarico, John A.; Roger, Pierre P.; Toste, F. Dean; Chang, Christopher J.

研究方向

暂未获取到该数据
M
Markus Schirle
H 指数:52论文数:143被引数:1.9万
S
Stephanie Moquin
H 指数:18论文数:51被引数:3,690
D
Daniel K. Nomura
H 指数:80论文数:294被引数:2.5万
J
John A. Tallarico
H 指数:49论文数:126被引数:1.1万
J
Jeffrey M. McKenna
H 指数:28论文数:88被引数:4,301
C
Celia A. Schiffer
H 指数:64论文数:422被引数:1.2万
N
Neşe Kurt Yılmaz
H 指数:31论文数:137被引数:3,355
M
Matthew J. Hesse
H 指数:15论文数:57被引数:1,223
D
Daniel N. Bolon
H 指数:43论文数:138被引数:6,013
A
Ala M. Shaqra
H 指数:10论文数:36被引数:562