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Compound PZ-1262, a 4-isoquinoline-sulfonamide analog of Brexpiprazole, produces potential antidepressant, anxiolytic and procognitive effects in rodent models Partyka, Anna; Golebiowska, Joanna; Marciniec, Krzysztof; Canale, Vittorio; Trybala, Wojciech; Satala, Grzegorza; Grychowska, Katarzyna; Jastrzebska-Wiesek, Magdalena; Bojarski, Andrzej J.; Nikiforuk, Agnieszka; Daniel, Wladyslawa A.; Wesolowska, Anna; Zajdel, Pawel; Popik, Piotr 分享 收藏
Simultaneous 5-HT1BR agonist/5-HT6R antagonist action as a potential treatment of Parkinson's disease and its comorbidities Zajdel, Pawe l; Matloka, Mikolaj; Konieczny, Jolanta; Kos, Tomasz; Lammers, Josie C.; Cavalco, Natalie G.; Clark, Allison A.; Lenda, Tomasz; Satala, Grzegorz; Canale, Vittorio; Grychowska, Katarzyna; Krawczyk, Martyna; Nikiforuk, Agnieszka; Partyka, Anna; Jastrzebska-Wiesek, Magdalena; Berghauzen-Maciejewska, Klemencja; Biala, Dominika; Janicka, Monika; Janusz, Artur; Piast, Radoslaw; Mulewski, Krzysztof; Smuga, Damian; Pieczykolan, Jerzy; Wieczorek, Maciej; Moszczynski-Petkowski, Rafal; Dubiel, Krzysztof; Ossowska, Krystyna; Bojarski, Andrzej J.; Kaminski, Krzysztof; Mccorvy, John D.; Popik, Piotr 分享 收藏
The Importance of Stereochemistry in 5-HT7R Modulation-A Case Study of Hydantoin Derivatives Kucwaj-Brysz, Katarzyna; Bas, Sebastian; Zeslawska, Ewa; Podlewska, Sabina; Jastrzebska-Wiesek, Magdalena; Partyka, Anna; Nitek, Wojciech; Satala, Grzegorz; Wesolowska, Anna; Handzlik, Jadwiga 分享 收藏
Contilisant plus Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases Toledano-Pinedo, Mireia; Porro-Perez, Alicia; Schaeker-Huebner, Linda; Romero, Fernando; Dong, Min; Samadi, Abdelouahid; Almendros, Pedro; Iriepa, Isabel; Bautista-Aguilera, Oscar M.; Rodriguez-Fernandez, M. Mercedes; Solana-Manrique, Cristina; Sanchis, Inmaculada; Mora-Morell, Alba; Rodriguez, Ania Canseco; Sanchez-Perez, Ana M.; Knez, Damijan; Gobec, Stanislav; Bellver-Sanchis, Aina; Perez, Belen; Dobrydnev, Alexey V.; Artetxe-Zurutuza, Aizpea; Matheu, Ander; Siwek, Agata; Wolak, Malgorzata; Satala, Grzegorz; Bojarski, Andrzej J.; Doroz-Plonka, Agata; Handzlik, Jadwiga; Godyn, Justyna; Wieckowska, Anna; Paricio, Nuria; Grinan-Ferre, Christian; Hansen, Finn K.; Marco-Contelles, Jose 分享 收藏
5-HT6 receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives Drop, Marcin; Koczurkiewicz-Adamczyk, Paulina; Bento, Ophelie; Pietrus, Wojciech; Satala, Grzegorz; Blicharz-Futera, Klaudia; Canale, Vittorio; Grychowska, Katarzyna; Bantreil, Xavier; Pekala, Elzbieta; Kurczab, Rafal; Bojarski, Andrzej J.; Chaumont-Dubel, Severine; Marin, Philippe; Lamaty, Frederic; Zajdel, Pawe l 分享 收藏
Discovery of WRN inhibitors as targeted therapy in the treatment of microsatellite unstable (MSI-H) tumors Schonemann, Wojciech; Ludwig-Slomczynska, Agnieszka; Dudek, Lukasz; Krol, Marcin; Farinone, Marco; Kulesza, Urszula; Jasnosz, Wojciech; Mac, Izabela; Zuchowicz, Karol; Wierzbicka, Katarzyna; Buchcic-Szychowska, Aleksandra; Gondela, Andrzej; Zagorska, Anna; Matuszewska, Oliwia; Sowinska, Marta; Nowogrodzki, Marcin; Girardi, Marianna; Paluch, Szymon; Sukhomlinova, Svitlana; Chlopek, Agata; Levenets, Iana; Kozlowska-Tomczyk, Kamila; Lagosz-Cwik, Katarzyna; Stoszko, Mateusz; Woroszylo, Szymon; Mikulski, Maciej; Jablonska, Justyna; Wisniewska, Magdalena; Palus-Chramiec, Katarzyna; Podkalicka-Golda, Paulina; Janiga, Anita; Sudol-Talaj, Sylwia; Sieprawska-Lupa, Magdalena; Miodek, Magdalena; Faber, Jacek; Starczak, Roza; Winnik, Bozena; Swirska, Agnieszka; Kowal-Chwast, Anna; Gogola, Dawid; Ratajczak, Sanja Novak; Dudek, Agata; Gaud, Nilesh; Satala, Grzegorz; Stachowicz, Agata; Swarbrick, Martin; Brzozka, Krzysztof; Zawadzka, Magdalena I. 分享 收藏
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease Pyka, Patryk; Haberek, Wawrzyniec; Wiecek, Malgorzata; Szymanska, Ewa; Ali, Wesam; Cios, Agnieszka; Jastrzebska-Wiesek, Magdalena; Satala, Grzegorz; Podlewska, Sabina; Di Giacomo, Silvia; Di Sotto, Antonella; Garbo, Sabrina; Karcz, Tadeusz; Lambona, Chiara; Marocco, Francesco; Latacz, Gniewomir; Sudol-Talaj, Sylwia; Mordyl, Barbara; Gluch-Lutwin, Monika; Siwek, Agata; Czarnota-Lydka, Kinga; Gogola, Dawid; Olejarz-Maciej, Agnieszka; Wilczynska-Zawal, Natalia; Honkisz-Orzechowska, Ewelina; Starek, Malgorzata; Dabrowska, Monika; Kucwaj-Brysz, Katarzyna; Fioravanti, Rossella; Nasim, Muhammad Jawad; Hittinger, Marius; Partyka, Anna; Wesolowska, Anna; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga 分享 收藏
Hydrophobicity modulation via the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against Alzheimer's disease for potent serotonin 5-HT6R agents Sudol-Talaj, Sylwia; Kucwaj-Brysz, Katarzyna; Podlewska, Sabina; Kurczab, Rafal; Satala, Grzegorz; Mordyl, Barbara; Gluch-Lutwin, Monika; Wilczynska-Zawal, Natalia; Jastrzebska-Wiesek, Magdalena; Czarnota-Lydka, Kinga; Kurowska, Kinga; Kubacka, Monika; Zeslawska, Ewa; Nitek, Wojciech; Olejarz-Maciej, Agnieszka; Doroz-Plonka, Agata; Partyka, Anna; Latacz, Gniewomir; Wesolowska, Anna; Handzlik, Jadwiga 分享 收藏
Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease Czarnota-Lydka, Kinga; Sudol-Talaj, Sylwia; Kucwaj-Brysz, Katarzyna; Kurczab, Rafal; Satala, Grzegorz; de Candia, Modesto; Samarelli, Francesco; Altomare, Cosimo Damiano; Carocci, Alessia; Barbarossa, Alexia; Zeslawska, Ewa; Gluch-Lutwin, Monika; Mordyl, Barbara; Kubacka, Monika; Wilczynska-Zawal, Natalia; Jastrzebska-Wiesek, Magdalena; Partyka, Anna; Khan, Nadia; Wiecek, Malgorzata; Nitek, Wojciech; Honkisz-Orzechowska, Ewelina; Latacz, Gniewomir; Wesolowska, Anna; Carrieri, Antonio; Handzlik, Jadwiga 分享 收藏
Superiority of the Triple-Acting 5-HT6R/5-HT3R Antagonist and MAO-B Reversible Inhibitor PZ-1922 over 5-HT6R Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats Grychowska, Katarzyna; Lopez-Sanchez, Uriel; Vitalis, Mathieu; Canet, Geoffrey; Satala, Grzegorz; Olejarz-Maciej, Agnieszka; Golebiowska, Joanna; Kurczab, Rafal; Pietrus, Wojciech; Kubacka, Monika; Moreau, Christophe; Walczak, Maria; Blicharz-Futera, Klaudia; Bantreil, Xavier; Subra, Gilles; Bojarski, Andrzej J.; Lamaty, Frederic; Becamel, Carine; Zussy, Charleine; Chaumont-Dubel, Severine; Popik, Piotr; Nury, Hugues; Marin, Philippe; Givalois, Laurent; Zajdel, Pawel 分享 收藏
Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats Kiilerich, Kat F.; Lorenz, Joe; Scharff, Malthe B.; Speth, Nikolaj; Brandt, Tobias G.; Czurylo, Julia; Xiong, Mengfei; Jessen, Naja S.; Casado-Sainz, Agata; Shalgunov, Vladimir; Kjaerby, Celia; Satala, Grzegorz; Bojarski, Andrzej J.; Jensen, Anders A.; Herth, Matthias M.; Cumming, Paul; Overgaard, Agnete; Palner, Mikael 分享 收藏
Amisulpride as a potential disease-modifying drug in the treatment of tauopathies Jahreis, Kathrin; Bruege, Alina; Borsdorf, Saskia; Mueller, Franziska E.; Sun, Weilun; Jia, Shaobo; Kang, Dong Min; Boesen, Nicolette; Shin, Seulgi; Lim, Sungsu; Koroleva, Anastasia; Satala, Grzegorz; Bojarski, Andrzej J.; Rakusa, Elena; Fink, Anne; Doblhammer-Reiter, Gabriele; Kim, Yun Kyung; Dityatev, Alexander; Ponimaskin, Evgeni; Labus, Josephine 分享 收藏
Discovery of novel MTA-cooperative PRMT5 inhibitors as targeted therapeutics for MTAP-deleted cancers Bartosik, Anna; Radzimierski, Adam; Bobowska, Aneta; Levenets, Oleksandr; Stachowicz, Agata; Kus, Kamil; Michalik, Kinga; Banaszak, Katarzyna; Madej, Monika; Skoda, Marta; Kozlowska-Tomczyk, Kamila; Tomczyk, Igor; Pyziak, Karolina; Krzemien, Dobroslawa; Gladysz, Miroslawa; Podkalicka, Paulina; Golas, Aniela; Gluza, Karolina; Satala, Grzegorz; Gondela, Andrzej; Sowinska, Marta; Boutard, Nicolas; Chlopek, Agata; Wieckowska, Aleksandra; Szukiel, Daria; Cwiertnia, Grzegorz; Levenets, Iana; Zuchowicz, Karol; Korta-Piatek, Klara; Nowogrodzki, Marcin; Wronowski, Marek; Girardi, Marianna; Swirski, Mateusz; Popika, Oleksandr; Niedziejko-Cwiertnia, Paulina; Cordone, Pierpaolo; Wyrebek, Przemyslaw; Vu, Qu. Nh; Sasmal, Sujit; Sukhomlinova, Svitlana; Miodek, Magdalena; Faber, Jacek; Kowal-Chwast, Anna; Starczak, Roza; Ratajczak, Sanja Novak; Swirska, Agnieszka; Gogola, Dawid; Guzik, Pawel; Swarbrick, Martin; Nowak, Mateusz 分享 收藏
New Triazine Derivatives as Serotonin 5-HT6 Receptor Ligands Lazewska, Dorota; Wiecek, Malgorzata; Satala, Grzegorz; Chalupnik, Paulina; Zeslawska, Ewa; Honkisz-Orzechowska, Ewelina; Tarasek, Monika; Latacz, Gniewomir; Nitek, Wojciech; Szymanska, Ewa; Handzlik, Jadwiga 分享 收藏
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