Keith T. Gagnon - Publications, H-index & Citations

Keith T. Gagnon

Wake Forest University School of Medicine

26H指数

70论文数

2.5K被引数

收录论文 36

发表时间

CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif CRISPR RNA 架构通过引导重复夹持基序引导 Cas9 催化作用和保真度

Nucleic Acids Research

IF13.1

2026-08-14

OAAI

Ramadevi Chilamkurthy; Sruthi Sudhakar; Adrian A Pater; Michael S Bosmeny; Francis Stabile; Adam Katolik; S Harikrishna; Fatima El Azzouzi; Rolf Turk; Masad J Damha; Sabrina Leslie; Sergey Korolev; P I Pradeepkumar; Keith T Gagnon; null

Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides 氟化反义寡核苷酸直接靶向C9ORF72重复RNA

Nucleic Acids Research

IF13.1

2026-04-25

OAAI

Halle M Barber; Mansi A Parasrampuria; Jerónimo Jurado-Arjona; Andrea Gamir-Morralla; Benedikt Berninger; Carlos González; Keith T Gagnon; Masad J Damha; Miguel Garavís; null

A nanopore-based HIV-1 reference epitranscriptome 基于纳米孔的HIV-1参考表观转录组

Nucleic Acids Research

IF13.1

2026-04-13

PREAI

Bosmeny, Michael S.; Pater, Adrian A.; Zhang, Li; Larkai, Lydia L.; Sha, Beverly E.; Lyu, Zidi; Damha, Masad J.; Mamede, Joao, I; Gagnon, Keith T.

Synthesis of long and functionally active RNAs facilitated by acetal levulinic ester chemistry 利用乙缩醛糠酸酯化学促进长功能活性RNA的合成

Nucleic Acids Research

IF13.1

2026-01-27

PREAI

Lyu, Zidi; Katolik, Adam; Yaseen, Iqra; Pater, Adrain A.; Robert, Francis; Huang, Sidong; Gagnon, Keith T.; Unrau, Peter J.; Damha, Masad J.

Resolving sequencing-based HIV-1 epitranscriptomics 解析基于测序的HIV-1表观转录组学

EPIGENOMICS

IF2.6

2025-05-16

PREAI

Bosmeny, Michael S.; Mamede, Joao I.; Gagnon, Keith T.

Chemical engineering of CRISPR-Cas systems for therapeutic application 用于治疗应用的crispr-cas系统的化学工程

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-12-17

PREAI

Barber, Halle M.; Pater, Adrian A.; Gagnon, Keith T.; Damha, Masad J.; O'Reilly, Daniel

Microprobes for Label-Free Detection of Short Tandem Repeats: An Insight into Alleviating Secondary Structure Effects

ANALYTICAL CHEMISTRY

IF6.7

2023-08-31

PREAI

Adil, Omair; Eddington, Seth B.; Gagnon, Keith T.; Shamsi, Mohtashim H.

Global mpox lineage discovery and rapid outbreak tracking with nanopore sequencing

VIROLOGY JOURNAL

IF3.8

2023-05-06

OAAI

Bosmeny, Michael S. S.; White, Adam A. A.; Pater, Adrian A. A.; Crew, Jennifer; Geltz, Joshua; Gagnon, Keith T. T.

Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-05-01

OAAI

Sudhakar, Sruthi; Barkau, Christopher L.; Chilamkurthy, Ramadevi; Barber, Halle M.; Pater, Adrian A.; Moran, Sean D.; Damha, Masad J.; Pradeepkumar, P. I.; Gagnon, Keith T.

Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles

NATURE COMMUNICATIONS

IF15.7

2021-11-15

OAAI

Ageely, Eman A.; Chilamkurthy, Ramadevi; Jana, Sunit; Abdullahu, Leonora; O'Reilly, Daniel; Jensik, Philip J.; Damha, Masad J.; Gagnon, Keith T.

Small nucleic acids and the path to the clinic for anti-CRISPR

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-07-01

OAAI

Barkau, Christopher L.; O'Reilly, Daniel; Eddington, Seth B.; Damha, Masad J.; Gagnon, Keith T.

Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Kartje, Zachary J.; Janis, Helen, I; Mukhopadhyay, Shaoni; Gagnon, Keith T.

Label-free Electrochemical Detection of CGG Repeats on Inkjet Printable 2D Layers of MoS2

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2020-11-05

PREAI

Asefifeyzabadi, Narges; Alkhaldi, Rana; Qamar, Ahmad Z.; Pater, Adrian A.; Patwardhan, Meera; Gagnon, Keith T.; Talapatra, Saikat; Shamsi, Mohtashim H.

Effect of 2′-5′/3′-5′ phosphodiester linkage heterogeneity on RNA interference

NUCLEIC ACIDS RESEARCH

IF13.1

2020-04-13

OAAI

Habibian, Maryam; Harikrishna, S.; Fakhoury, Johans; Barton, Maria; Ageely, Eman A.; Cencic, Regina; Fakih, Hassan H.; Katolik, Adam; Takahashi, Mayumi; Rossi, John; Pelletier, Jerry; Gagnon, Keith T.; Pradeepkumar, P., I; Damha, Masad J.

Systematic microsatellite repeat expansion cloning and validation

HUMAN GENETICS

IF3.6

2020-04-10

OAAI

Rohilla, Kushal J.; Ovington, Katy N.; Pater, Adrian A.; Barton, Maria; Henke, Anthony J.; Gagnon, Keith T.

Novel probes for label-free detection of neurodegenerative GGGGCC repeats associated with amyotrophic lateral sclerosis

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2019-08-21

OAAI

Taki, Motahareh; Rohilla, Kushal J.; Barton, Maria; Funneman, Madison; Benzabeh, Najiyah; Naphade, Swati; Ellerby, Lisa M.; Gagnon, Keith T.; Shamsi, Mohtashim H.

Rationally Designed Small Nucleic Acid-Based Inhibitors of CRISPR-Cas9 合理设计的基于小核酸的CRISPR-Cas9抑制剂

NUCLEIC ACID THERAPEUTICS

IF4.7

2019-06-01

OAAI

Barkau, Christopher L.; O'Reilly, Daniel; Rohilla, Kushal J.; Damha, Masad J.; Gagnon, Keith T.

Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs

NUCLEIC ACID THERAPEUTICS

IF4.7

2019-06-01

OAAI

Gagnon, Keith T.; Corey, David R.

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity

NUCLEIC ACIDS RESEARCH

IF13.1

2018-12-04

OAAI

O'Reilly, Daniel; Kartje, Zachary J.; Ageely, Eman A.; Malek-Adamian, Elise; Habibian, Maryam; Schofield, Annabelle; Barkau, Christopher L.; Rohilla, Kushal J.; DeRossett, Lauren B.; Weigle, Austin T.; Damha, Masad J.; Gagnon, Keith T.

RNA biology of disease-associated microsatellite repeat expansions

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2017-08-29

OAAI

Rohilla, Kushal J.; Gagnon, Keith T.

研究方向