Paula M. Canas - Publications, H-index & Citations

Paula M. Canas

cibb

38H指数

84论文数

4.5K被引数

收录论文 39

发表时间

Genetic deletion of adenosine A2A receptors attenuates memory deterioration and alterations of synaptic plasticity and metabolic controllers in the hippocampus and prefrontal cortex of aged mice 腺苷A2A受体基因敲除可减轻老年小鼠海马体和前额叶皮层中的记忆衰退以及突触可塑性和代谢调控因子的改变。

GeroScience

IF5.4

2026-03-30

OAAI

Cátia R. Lopes; Daniela Madeira; Madalena Piteira; Pedro Valada; Joana Santos; Henrique B. Silva; Francisco Q. Gonçalves; Ângelo R. Tomé; Paula M. Canas; João Pedro Lopes; Samira G. Ferreira; Paula Agostinho; Rodrigo A. Cunha

Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-02-06

PREAI

Amorim, Joao A.; Canas, Paula M.; Tome, Angelo R.; Rolo, Anabela P.; Agostinho, Paula; Palmeira, Carlos M.; Cunha, Rodrigo A.

Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-10-29

OAAI

Madeira, Daniela; Domingues, Joana; Lopes, Catia R.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula

Adenosine A2A receptors control generalization of contextual fear in rats

TRANSLATIONAL PSYCHIATRY

IF6.2

2023-10-12

OAAI

Simoes, Ana P.; Portes, Marina A. M.; Lopes, Catia R.; Vanz, Felipe; Lourenco, Vanessa S.; Pliassova, Anna; Gaspar, Ingride L.; Silva, Henrique B.; Tome, Angelo R.; Canas, Paula M.; Prediger, Rui D.; Cunha, Rodrigo A.

Astrocytic A2A receptors silencing negatively impacts hippocampal synaptic plasticity and memory of adult mice 星形胶质细胞A2A受体沉默对成年小鼠海马突触可塑性和记忆的负面影响

GLIA

IF5.1

2023-05-15

PREAI

Madeira, Daniela; Lopes, Catia R.; Simoes, Ana P.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula

Redox signalling and proteostasis in neurodegeneration: In vivo effects of the mitochondria-targeted antioxidant MitoQ in Huntington's disease mice

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2023-03-01

PREAI

Pinho, Brigida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M. A.

Adenosine A2A receptors blockade attenuates dexamethasone-induced alterations in cultured astrocytes

PURINERGIC SIGNALLING

IF2.4

2022-04-27

OAAI

Madeira, Daniela; Dias, Liliana; Santos, Patricia; Cunha, Rodrigo A.; Agostinho, Paula; Canas, Paula M.

Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction

NEUROBIOLOGY OF DISEASE

IF5.6

2021-09-01

OAAI

Augusto, Elisabete; Goncalves, Francisco Q.; Real, Joana E.; Silva, Henrique B.; Pochmann, Daniela; Silva, Tiago S.; Matos, Marco; Goncalves, Nelio; Tome, Angelo R.; Chen, Jiang-Fan; Canas, Paula M.; Cunha, Rodrigo A.

Adenosine A2A Receptors as Biomarkers of Brain Diseases

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-07-16

OAAI

Moreira-de-Sa, Ana; Lourenco, Vanessa S.; Canas, Paula M.; Cunha, Rodrigo A.

Deletion of CD73 increases exercise power in mice

PURINERGIC SIGNALLING

IF2.4

2021-07-03

OAAI

Aguiar, Aderbal S., Jr.; Speck, Ana Elisa; Canas, Paula M.; Cunha, Rodrigo A.

L-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory

FASEB JOURNAL

IF4.2

2021-07-01

PREAI

Pereira, Marlene F.; Amaral, Ines M.; Lopes, Catia; Leitao, Catarina; Madeira, Daniela; Lopes, Joao P.; Goncalves, Francisco Q.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula

Use of knockout mice to explore CNS effects of adenosine

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-05-01

PREAI

Lopes, Catia R.; Lourenco, Vanessa S.; Tome, Angelo R.; Cunha, Rodrigo A.; Canas, Paula M.

Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

NEUROBIOLOGY OF DISEASE

IF5.6

2020-12-01

OAAI

Moreira-de-Sa, Ana; Goncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Tome, Angelo R.; Cunha, Rodrigo A.; Canas, Paula M.

Purinergic signaling orchestrating neuron-glia communication

PHARMACOLOGICAL RESEARCH

IF10.5

2020-12-01

PREAI

Agostinho, Paula; Madeira, Daniela; Dias, Liliana; Simoes, Ana Patricia; Cunha, Rodrigo A.; Canas, Paula M.

Neuronal adenosine A2A receptors signal ergogenic effects of caffeine

SCIENTIFIC REPORTS

IF3.9

2020-08-07

OAAI

Aguiar, Aderbal S., Jr.; Speck, Ana Elisa; Canas, Paula M.; Cunha, Rodrigo A.

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice 神经变性中氧化还原信号和蛋白稳态之间的相互作用: 线粒体靶向抗氧化剂在亨廷顿病小鼠中的体内作用

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2020-01-01

OAAI

Pinho, Brigida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M. A.

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

NEUROBIOLOGY OF DISEASE

IF5.6

2019-12-01

OAAI

Goncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Lemos, Cristina; Silva, Antonio C.; Goncalves, Nell; Tome, Angelo R.; Ferreira, Samira G.; Canas, Paula M.; Rial, Daniel; Agostinho, Paula; Cunha, Rodrigo A.

Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A2A receptor over-activation in a rat model of Parkinson's disease

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2019-08-01

OAAI

Carmo, Marta; Goncalves, Francisco Q.; Anas, Paula M. C.; Oses, Jean-Pierre; Fernandes, Francisco D.; Duarte, Filipe, V; Palmeira, Carlos M.; Tome, Angelo R.; Agostinho, Paula; Andrade, Geanne M.; Cunha, Rodrigo A.

Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in Rats

FRONTIERS IN NEUROSCIENCE

IF3.2

2018-09-21

OAAI

Moreira-Silva, Daniel; Carrettiero, Daniel C.; Oliveira, Adriele S. A.; Rodrigues, Samanta; dos Santos-Lopes, Joyce; Canas, Paula M.; Cunha, Rodrigo A.; Almeida, Maria C.; Ferreira, Tatiana L.

Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2018-09-01

PREAI

Silva, Antonio C.; Lemos, Cristina; Goncalves, Francisco Q.; Pliassova, Anna V.; Machado, Nuno J.; Silva, Henrique B.; Canas, Paula M.; Cunha, Rodrigo A.; Lopes, Joao Pedro; Agostinho, Paula

研究方向