György G. Ferenczy - Publications, H-index & Citations

György G. Ferenczy

Research Centre for Natural Sciences

31H指数

132论文数

4.0K被引数

收录论文 49

发表时间

α-Halothioamide warheads with enhanced cysteine reactivity and specificity for covalent protein labelling α-卤代硫酰胺基团作为具有增强半胱氨酸反应性和特异性的共价蛋白质标记物

Nature Communications

IF15.7

2026-05-14

OAAI

László Petri; Ronen Gabizon; Nikolett Péczka; Péter Ábrányi-Balogh; József Simon; Tímea Imre; György G. Ferenczy; Nir London; György M. Keserű

Covalent ligand efficiency 共价配体效率

Drug Discovery Today

IF7.5

2025-08-13

OAAI

György G. Ferenczy; György M. Keserű

Size-Dependent Target Engagement of Covalent Probes 尺寸依赖的共价探针靶点结合情况

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-03-18

OAAI

Petri, Laszlo; Gabizon, Ronen; Ferenczy, Gyorgy G.; Peczka, Nikolett; Egyed, Attila; Takacs, Tamas

Effect of Water Networks On Ligand Binding: Computational Predictions vs Experiments

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-11-22

PREAI

Szalai, Tibor Viktor; Bajusz, David; Borzsei, Rita; Zsido, Balazs Zoltan; Ilas, Janez; Ferenczy, Gyorgy G.; Hetenyi, Csaba; Keseru, Gyorgy M.

Comparative Study of Allosteric GPCR Binding Sites and Their Ligandability Potential

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-10-23

OAAI

Peter, Sonja; Siragusa, Lydia; Thomas, Morgan; Palomba, Tommaso; Cross, Simon; O'Boyle, Noel M.; Bajusz, David; Ferenczy, Gyorgy G.; Keseru, Gyorgy M.; Bottegoni, Giovanni; Bender, Brian; Chen, Ijen; De Graaf, Chris

Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors: A Case Study on KRasG12C 非共价识别和反应性对共价抑制剂优化的贡献: 以KRasG12C为例

ACS CHEMICAL BIOLOGY

IF3.8

2024-07-11

OAAI

Peczka, Nikolett; Randelovic, Ivan; Orgovan, Zoltan; Csorba, Noemi; Egyed, Attila; Petri, Laszlo; Abranyi-Balogh, Peter; Gadanecz, Marton; Perczel, Andras; Tovari, Jozsef; Schlosser, Gitta; Takacs, Tamas; Mihalovits, Levente M.; Ferenczy, Gyorgy G.; Buday, Laszlo; Keseru, Gyorgy M.

Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2024-02-27

OAAI

Kollar, Levente; Grabrijan, Katarina; Rambaher, Martina Hrast; Bozovicar, Kristof; Imre, Timea; Ferenczy, Gyorgy G.; Gobec, Stanislav; Keseru, Gyorgy M.

Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors 下一代杂环亲电试剂作为小分子共价MurA抑制剂

PHARMACEUTICALS

IF4.8

2022-11-29

OAAI

Abranyi-Balogh, Peter; Keeley, Aaron; Ferenczy, Gyorgy G.; Petri, Laszlo; Imre, Timea; Grabrijan, Katarina; Hrast, Martina; Knez, Damijan; Ilas, Janez; Gobec, Stanislav; Keseru, Gyorgy M.

The Structure-Derived Mechanism of Box H/ACA Pseudouridine Synthase Offers a Plausible Paradigm for Programmable RNA Editing

ACS CATALYSIS

IF13.1

2022-02-11

OAAI

Kiss, Dora Judit; Olah, Julianna; Toth, Gergely; Varga, Mate; Stirling, Andras; Menyhard, Dora K.; Ferenczy, Gyorgy G.

Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads 衍生自半胱氨酸和苏氨酸靶向弹头的片段大小和双齿 (免疫) 蛋白酶体抑制剂

CELLS

IF5.2

2021-12-06

OAAI

Kollar, Levente; Gobec, Martina; Proj, Matic; Smrdel, Lara; Knez, Damijan; Imre, Timea; Gomory, Agnes; Petri, Laszlo; Abranyi-Balogh, Peter; Csanyi, Dorottya; Ferenczy, Gyoergy G.; Gobec, Stanislav; Sosic, Izidor; Keseru, Gyoergy M.

Discovery of selective fragment-sized immunoproteasome inhibitors 选择性片段免疫蛋白酶体抑制剂的发现

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-07-01

PREAI

Kollar, Levente; Gobec, Martina; Szilagyi, Bence; Proj, Matic; Knez, Damijan; Abranyi-Balogh, Peter; Petri, Laszlo; Imre, Timea; Bajusz, David; Ferenczy, Gyorgy G.; Gobec, Stanislav; Keseru, Gyorgy M.; Sosic, Izidor

WIDOCK: a reactive docking protocol for virtual screening of covalent inhibitors WIDOCK: 用于虚拟筛选共价抑制剂的反应性对接协议

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2021-01-18

OAAI

Scarpino, Andrea; Petri, Laszlo; Knez, Damijan; Imre, Timea; abranyi-Balogh, Peter; Ferenczy, Gyorgy G.; Gobec, Stanislav; Keseru, Gyorgy M.

Affinity and Selectivity Assessment of Covalent Inhibitors by Free Energy Calculations

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-12-09

PREAI

Mihalovits, Levente M.; Ferenczy, Gyorgy G.; Keseru, Gyorgy M.

Allosteric Molecular Switches in Metabotropic Glutamate Receptors

CHEMMEDCHEM

IF3.4

2020-08-25

OAAI

Orgovan, Zoltan; Ferenczy, Gyorgy G.; Keseru, Gyorgy M.

Thermodynamic profiling for fragment-based lead discovery and optimization

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2019-11-19

OAAI

Ferenczy, Gyorgy G.; Keseru, Gyorgy M.

Catalytic Mechanism and Covalent Inhibition of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA): Implications to the Design of Novel Antibacterials

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-11-12

PREAI

Mihalovits, Levente M.; Ferenczy, Gyorgy G.; Keseru, Gyorgy M.

The role of water and protein flexibility in the structure-based virtual screening of allosteric GPCR modulators: an mGlu5 receptor case study

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2019-09-21

OAAI

Orgovan, Zoltan; Ferenczy, Gyorgy G.; Keseru, Gyorgy M.

Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening 使用大规模共价虚拟筛选发现免疫蛋白酶体抑制剂

MOLECULES

IF4.6

2019-07-16

OAAI

Scarpino, Andrea; Bajusz, David; Proj, Matic; Gobec, Martina; Sosic, Izidor; Gobec, Stanislav; Ferenczy, Gyoergy G.; Keseru, Gyoergy M.

Synthesis and Biochemical Evaluation of Lid-Open d-Amino Acid Oxidase Inhibitors

MOLECULES

IF4.6

2019-01-14

OAAI

Szilagyi, Bence; Hargitai, Csilla; Kelemen, Adam A.; Racz, Anita; Ferenczy, Gyoergy G.; Volk, Balazs; Keseru, Gyorgy M.

A road map for prioritizing warheads for cysteine targeting covalent inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-12-01

101

PREAI

Abranyi-Balogh, Peter; Petri, Laszlo; Imre, Timea; Szijj, Peter; Scarpino, Andrea; Hrast, Martina; Mitrovic, Ana; Fonovic, Ursa Petar; Nemeth, Krisztina; Barreteau, Helene; Roper, David I.; Horvati, Kata; Ferenczy, Gyorgy G.; Kos, Janko; Ilas, Janez; Gobec, Stanislav; Keseru, Gyorgy M.

研究方向