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Development of Potent and Selective Inhibitors of Methylenetetrahydrofolate Dehydrogenase 2 for Targeting Acute Myeloid Leukemia: SAR, Structural Insights, and Biological Characterization Chang, Hsin-Huei; Lee, Lung-Chun; Hsu, Tsu; Peng, Yi-Hui; Huang, Chih-Hsiang; Yeh, Teng-Kuang; Lu, Cheng-Tai; Huang, Zih-Ting; Hsueh, Ching-Cheng; Kung, Fang-Chun; Lin, Li-Mei; Huang, Yu-Chen; Wang, Yi-Hsin; Li, Li-Hsuan; Tang, Ya-Chu; Chang, Ling; Hsieh, Chih-Chien; Jiaang, Weir-Torn; Kuo, Ching-Chuan; Wu, Su-Ying 分享 收藏
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Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorder Liu, Fa-rong; Zhou, Yunqiang; Wang, Yong; Huang, Ling-ling; Zhang, Xian; Luo, Hong; Wu, Su-ying; Lyu, Hai-yan; Huang, Li-huan; Xu, Huaxi; Zhang, Yun-wu 分享 收藏
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Discovery and development of a novel N-(3-bromophenyl)- {[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design 使用基于知识的药物设计发现和开发新型N-(3-溴苯基)- {[(苯基氨基甲酰基) 氨基] 甲基}-N-hydroxythiophene-2-carboximidamide吲哚胺2，3-双加氧酶抑制剂 Yeh, Teng-Kuang; Song, Jen-Shin; Chang, Po-Wei; Yu, Jin-Chen; Chang, Chia-Hwa; Liao, Fang-Yu; Tien, Ya-Wen; Kuppusamy, Ramajayam; Li, An-Siou; Chen, Chi-Han; Chen, Chieh-Wen; Lin, Li-Mei; Chang, Hsin-Huei; Huang, Chih-Hsiang; Yao, Jau-Ying; Wu, Mine-Hsine; Peng, Yi-Hui; Hsueh, Ching-Cheng; Hsiao, Wen-Chi; Chen, Pei-Husan; Lin, Chin-Yu; Hsieh, Su-Huei; Shih, Chuan; Hung, Ming-Shiu; Wu, Su-Ying; Kuo, Ching-Chuan; Ueng, Shau-Hua 分享 收藏
Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) Lee, Lung-Chun; Peng, Yi-Hui; Chang, Hsin-Huei; Hsu, Tsu; Lu, Cheng-Tai; Huang, Chih-Hsiang; Hsueh, Ching-Cheng; Kung, Fang-Chun; Kuo, Ching-Chuan; Jiaang, Weir-Torn; Wu, Su-Ying 分享 收藏
LPS-Induced Inflammation Affects Midazolam Clearance in Juvenile Mice in an Age-Dependent Manner Zheng, Yi; Ye, Pan-Pan; Zhou, Yue; Wu, Su-Ying; Liu, Xi-Ting; Du, Bin; Tang, Bo-Hao; Kan, Min; Nie, Ai-Qing; Yin, Rui; Wang, Meng; Hao, Guo-Xiang; Song, Lin-Lin; Yang, Xin-Mei; Huang, Xin; Su, Le-Qun; Wang, Wen-Qi; van den Anker, John; Zhao, Wei 分享 收藏
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Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors (vol 63, pg 1642, 2020) Peng, Yi-Hui; Liao, Fang-Yu; Tseng, Chen-Tso; Kuppusamy, Ramajayam; Li, An-Siou; Chen, Chi-Han; Fan, Yu-Shiou; Wang, Sing-Yi; Wu, Mine-Hsine; Hsueh, Ching-Cheng; Chang, Jia-Yu; Lee, Lung-Chun; Shih, Chuan; Shia, Kak-Shan; Yeh, Teng-Kuang; Hung, Ming-Shiu; Kuo, Ching-Chuan; Song, Jen-Shin; Wu, Su-Ying; Ueng, Shau-Hua 分享 收藏
Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors Peng, Yi-Hui; Liao, Fang-Yu; Tseng, Chen-Tso; Kuppusamy, Ramajayam; Li, An-Siou; Chen, Chi-Han; Fan, Yu-Shiou; Wang, Sing-Yi; Wu, Mine-Hsine; Hsueh, Ching-Cheng; Chang, Jia-Yu; Lee, Lung-Chun; Shih, Chuan; Shia, Kak-Shan; Yeh, Teng-Kuang; Hung, Ming-Shiu; Kuo, Ching-Chuan; Song, Jen-Shin; Wu, Su-Ying; Ueng, Shau-Hua 分享 收藏
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Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia Lin, Wen-Hsing; Wu, Su-Ying; Yeh, Teng-Kuang; Chen, Chiung-Tong; Song, Jen-Shin; Shiao, Hui-Yi; Kuo, Ching-Chuan; Hsu, Tsu; Lu, Cheng-Tai; Wang, Pei-Chen; Wu, Tsung-Sheng; Peng, Yi-Hui; Lin, Hui-You; Chen, Ching-Ping; Weng, Ya-Ling; Kung, Fang-Chun; Wu, Mine-Hsine; Su, Yu-Chieh; Huang, Kuo-Wei; Chou, Ling-Hui; Hsueh, Ching-Cheng; Yen, Kuei-Jung; Kuo, Po-Chu; Huang, Chen-Lung; Chen, Li-Tzong; Shih, Chuan; Tsai, Hui-Jen; Jiaang, Weir-Torn 分享 收藏
Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer Lin, Shu-Yu; Hsu, Yung Chang; Peng, Yi-Hui; Ke, Yi-Yu; Lin, Wen-Hsing; Sun, Hsu-Yi; Shiao, Hui-Yi; Kuo, Fu-Ming; Chen, Pei-Yi; Lien, Tzu-Wen; Chen, Chun-Hwa; Chu, Chang-Ying; Wang, Sing-Yi; Yeh, Kai-Chia; Chen, Ching-Ping; Hsu, Tsu-An; Wu, Su-Ying; Yeh, Teng-Kuang; Chen, Chiung-Tong; Hsieh, Hsing-Pang 分享 收藏
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants Wu, Tsung-Sheng; Lin, Wen-Hsing; Tsai, Hui-Jen; Hsueh, Ching-Cheng; Hsu, Tsu; Wang, Pei-Chen; Lin, Hui-You; Peng, Yi-Hui; Lu, Cheng-Tai; Lee, Lung-Chun; Tu, Chih-Hsiang; Kung, Fang-Chun; Shiao, Hui-Yi; Yeh, Teng-Kuang; Song, Jen-Shin; Chang, Jia-Yu; Su, Yu-Chieh; Chen, Li-Tzong; Chen, Chiung-Tong; Jiaang, Weir -Torn; Wu, Su-Ying 分享 收藏
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Pyrazolylamine Derivatives Reveal the Conformational Switching between Type I and Type II Binding Modes of Anaplastic Lymphoma Kinase (ALK) Tu, Chih-Hsiang; Lin, Wen-Hsing; Peng, Yi-Hui; Hsu, Tsu; Wu, Jian-Sung; Chang, Chun-Yu; Lu, Cheng-Tai; Lyu, Ping-Chiang; Shih, Chuan; Jiaang, Weir-Torn; Wu, Su-Ying 分享 收藏
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