未登录

J

Jingde Wu

Shandong University

H指数:21

被引数:1,425

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Discovery of potent Type-II GSK-3β/VEGFR2 inhibitors with promising potential against tongue squamous cell carcinoma

发现具有抗舌鳞状细胞癌潜力的强效II型GSK-3β/VEGFR2抑制剂

European Journal of Medicinal Chemistry

IF5.9

2026-09-290

PRE

Development of novel quinoline derivatives as selective HDAC6 inhibitors exhibiting multiple anticancer effects

新型喹啉衍生物作为选择性HDAC6抑制剂的研发及其多重抗肿瘤效应的展示

Bioorganic Chemistry

IF4.7

2026-05-250

PRE

HDAC8 as a target in drug discovery: Function, structure and design

HDAC8作为药物发现的靶标: 功能，结构和设计

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-010

PRE

Design, synthesis, and biological evaluation of novel N-Benzyl piperidine derivatives as potent HDAC/AChE inhibitors for Alzheimer's disease

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-02-0116

PRE

A branched small molecule-drug conjugate nanomedicine strategy for the targeted HCC chemotherapy

用于靶向HCC化疗的分支小分子-药物缀合物纳米医学策略

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-01-019

PRE

Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-12-0116

PREAI

SAR Investigation and Discovery of Water-Soluble 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazoles as Potent Tubulin Polymerization Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-11-1720

PREAI

Development of small molecule inhibitors targeting NLRP3 inflammasome pathway for inflammatory diseases

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-01-01116

PREAI

Glycyrrhetinic acid-modified graphene oxide mediated siRNA delivery for enhanced liver-cancer targeting therapy

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2019-11-0142

PREAI

Design, synthesis and activity evaluation of indole-based double - Branched HDAC1 inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2019-04-0111

PREAI

Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties

INVESTIGATIONAL NEW DRUGS

IF2.7

2019-03-185

PREAI

Development of Bruton's Tyrosine Kinase Inhibitors for Rheumatoid Arthritis

CURRENT MEDICINAL CHEMISTRY

IF3.5

2019-02-0622

PRE

Advances on graphene-based nanomaterials for biomedical applications

石墨烯基纳米材料在生物医学中的应用研究进展

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

IF8.1

2018-09-01121

PREAI

Structure optimization and preliminary bioactivity evaluation of N-hydroxybenzamide-based HDAC inhibitors with Y-shaped cap

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2018-05-0113

PREAI

Design, synthesis and tumor cell growth inhibitory activity of 3-nitro-2H-cheromene derivatives as histone deacetylaes inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-08-0121

PREAI

Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel NLRP3 lnflammasome Inhibitor for Potential Treatment of Multiple Sclerosis

ACS CHEMICAL NEUROSCIENCE

IF3.9

2017-07-1391

OAAI

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-07-0134

OAAI

Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-11-0116

PREAI

Design, synthesis, and preliminary bioactivity evaluation of N1-hydroxyterephthalamide derivatives with indole cap as novel histone deacetylase inhibitors

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2016-10-2622

OAAI

Design, synthesis, and biological characterization of tamibarotene analogs as anticancer agents

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2016-06-0110

PREAI