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C

Carrow I. Wells

University of North Carolina at Chapel Hill Eshelman School of Pharmacy
H指数:26
被引数:2,787

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工作经历

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荣誉奖项

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Targeting STK17B kinase activates ferroptosis and suppresses drug resistance in multiple myeloma

靶向STK17B激酶能激活铁死亡并抑制多发性骨髓瘤中的药物抵抗

Blood
IF23.1
2025-09-150
PRE
Zhibo Yan; Zhannan Han; Yihui Wang; Maja Beus; Yu Zhang; Alfredo Picado; Carrow I. Wells; Jian Wu; Loren B. Weidenhammer; Karla M. Pires; Elizabeth A. Leibold; Liang Liu; David M. Gooden; Ivan Spasojevic; Erik J. Soderblom; Yubin Kang; Lawrence H. Boise; Timothy M. Willson; Mikhail A. Nikiforov
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-07-180
OAAI
Nemec, Vaclav; Remes, Marek; Benovsky, Petr; Boeck, Michael C.; Srankova, Eliska; Wong, Jong Fu; Cros, Julien; Williams, Eleanor; Tse, Lap Hang; Smil, David; Ensan, Deeba; Isaac, Methvin B.; Al-Awar, Rima; Gomolkova, Regina; Ursachi, Vlad-Constantin; Fafilek, Bohumil; Kahounova, Zuzana; Vichova, Rachel; Vacek, Ondrej; Berger, Benedict-Tilman; Wells, Carrow I.; Corona, Cesear R.; Vasta, James D.; Robers, Matthew B.; Krejci, Pavel; Soucek, Karel; Bullock, Alex N.; Knapp, Stefan; Paruch, Kamil
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals
JOURNAL OF PROTEOME RESEARCH
IF3.6
2023-08-278
PRE
Fritch, Ethan J.; Mordant, Angie L.; Gilbert, Thomas S. K.; Wells, Carrow I.; Yang, Xuan; Barker, Natalie K.; Madden, Emily A.; Dinnon, Kenneth H., III; Hou, Yixuan J.; Tse, Longping V.; Castillo, Izabella N.; Sims, Amy C.; Moorman, Nathaniel J.; Lakshmanane, Premkumar; Willson, Timothy M.; Herring, Laura E.; Graves, Lee M.; Baric, Ralph S.
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective

发现具有神经保护作用的有效且选择性的CDKL5/GSK3化学探针

ACS CHEMICAL NEUROSCIENCE
IF3.9
2023-04-214
OAAI
Ong, Han Wee; Liang, Yi; Richardson, William; Lowry, Emily R.; Wells, Carrow I.; Chen, Xiangrong; Silvestre, Margaux; Dempster, Kelvin; Silvaroli, Josie A.; Smith, Jeffery L.; Wichterle, Hynek; Pabla, Navjot S.; Ultanir, Sila K.; Bullock, Alex N.; Drewry, David H.; Axtman, Alison D.
SGC-CAMKK2-1: A Chemical Probe for CAMKK2

SGC-CAMKK2-1: CAMKK2的化学探针

CELLS
IF5.2
2023-01-114
OAAI
Wells, Carrow; Liang, Yi; Pulliam, Thomas L.; Lin, Chenchu; Awad, Dominik; Eduful, Benjamin; O'Byrne, Sean; Hossain, Mohammad Anwar; Catta-Preta, Carolina Moura Costa; Ramos, Priscila Zonzini; Gileadi, Opher; Gileadi, Carina; Counago, Rafael M.; Stork, Brittany; Langendorf, Christopher G.; Nay, Kevin; Oakhill, Jonathan S.; Mukherjee, Debarati; Racioppi, Luigi; Means, Anthony R.; York, Brian; McDonnell, Donald P.; Scott, John W.; Frigo, Daniel E.; Drewry, David H.
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas
SCIENCE ADVANCES
IF12.5
2022-06-248
OAAI
Tiek, Deanna M.; Erdogdu, Beril; Razaghi, Roham; Jin, Lu; Sadowski, Norah; Alamillo-Ferrer, Carla; Hogg, J. Robert; Haddad, Bassem R.; Drewry, David H.; Wells, Carrow, I; Pickett, Julie E.; Song, Xiao; Goenka, Anshika; Hu, Bo; Goldlust, Samuel A.; Zuercher, William J.; Pertea, Mihaela; Timp, Winston; Cheng, Shi-Yuan; Riggins, Rebecca B.
AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS
IF6.8
2022-04-203
OAAI
Potjewyd, Frances M.; Annor-Gyamfi, Joel K.; Aube, Jeffrey; Chu, Shaoyou; Conlon, Ivie L.; Frankowski, Kevin J.; Guduru, Shiva K. R.; Hardy, Brian P.; Hopkins, Megan D.; Kinoshita, Chizuru; Kireev, Dmitri B.; Mason, Emily R.; Moerk, Charles T.; Nwogbo, Felix; Pearce, Kenneth H.; Richardson, Timothy, I; Rogers, David A.; Soni, Disha M.; Stashko, Michael; Wang, Xiaodong; Wells, Carrow; Willson, Timothy M.; Frye, Stephen, V; Young, Jessica E.; Axtman, Alison D.
Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS
IF6.8
2022-04-124
OAAI
Potjewyd, Frances M.; Annor-Gyamfi, Joel K.; Aube, Jeffrey; Chu, Shaoyou; Conlon, Ivie L.; Frankowski, Kevin J.; Guduru, Shiva K. R.; Hardy, Brian P.; Hopkins, Megan D.; Kinoshita, Chizuru; Kireev, Dmitri B.; Mason, Emily R.; Moerk, Charles T.; Nwogbo, Felix; Pearce, Kenneth H.; Richardson, Timothy, I; Rogers, David A.; Soni, Disha M.; Stashko, Michael; Wang, Xiaodong; Wells, Carrow; Willson, Timothy M.; Frye, Stephen, V; Young, Jessica E.; Axtman, Alison D.
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

铰链粘合剂支架跳跃识别有效的钙/钙调蛋白依赖性蛋白激酶激酶2 (CAMKK2) 抑制剂化学型

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-07-1520
OAAI
Eduful, Benjamin J.; O'Byrne, Sean N.; Temme, Louisa; Asquith, Christopher R. M.; Liang, Yi; Picado, Alfredo; Pilotte, Joseph R.; Hossain, Mohammad Anwar; Wells, Carrow, I; Zuercher, William J.; Catta-Preta, Carolina M. C.; Ramos, Priscila Zonzini; Santiago, Andre de S.; Counago, Rafael M.; Langendorf, Christopher G.; Nay, Kevin; Oakhill, Jonathan S.; Pulliam, Thomas L.; Lin, Chenchu; Awad, Dominik; Willson, Timothy M.; Frigo, Daniel E.; Scott, John W.; Drewry, David H.
NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells
BREAST CANCER RESEARCH AND TREATMENT
IF3
2021-07-0110
OAAI
Matossian, Margarite D.; Elliott, Steven; Van Hoang, T.; Burks, Hope E.; Wright, Maryl K.; Alzoubi, Madlin S.; Yan, Thomas; Chang, Tiffany; Wathieu, Henri; Windsor, Gabrielle O.; Hartono, Alifiani Bo; Lee, Sean; Zuercher, William J.; Drewry, David H.; Wells, Carrow; Kapadia, Nirav; Buechlein, Aaron; Fang, Fang; Nephew, Kenneth P.; Collins-Burow, Bridgette M.; Burow, Matthew E.

研究方向

暂未获取到该数据
D
David H. Drewry
H 指数:41论文数:276被引数:6,025
W
William J. Zuercher
H 指数:41论文数:230被引数:6,368
T
Timothy M. Willson
H 指数:110论文数:419被引数:6.8万
A
Alison D. Axtman
H 指数:17论文数:123被引数:1,169
J
Julie E. Pickett
H 指数:15论文数:51被引数:1,212
C
Christopher R. M. Asquith
H 指数:21论文数:165被引数:1,227
J
Jonathan M. Elkins
H 指数:38论文数:374被引数:6,244
T
Tuomo Laitinen
H 指数:29论文数:209被引数:2,398
R
Rafael M. Couñago
H 指数:25论文数:161被引数:1,827
J
James M. Bennett
H 指数:36论文数:166被引数:4,400