David H. Drewry - Publications, H-index & Citations

David H. Drewry

university of north carolina at chapel hill

41H指数

276论文数

6.0K被引数

收录论文 88

发表时间

Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders 靶向受体样酪氨酸激酶2的异双功能蛋白质降解剂

Journal of Medicinal Chemistry

IF6.8

2026-05-03

OAAI

Daniel T. Webb; Katherine L. Jones; Natsuko Macabuag; Ruzica Bago; Joshua Betts; Sumit Bhattacharyya; Steve Clifton; Ryan A. J. Tinson; Chigozie Achara; Simon Gilbert; Stefanie Howell; David H. Drewry; Rebecca Rogers; Chris Jones; Kyle R. Ferguson; Alex N. Bullock; David M. Lindsay; William J. Kerr; William Esmieu

Cellular Context Influences Kinase Inhibitor Selectivity

Journal of Medicinal Chemistry

IF6.8

2026-02-06

OAAI

Matthew J. Binder; Frances M. Bashore; Kaitlin K. Dunn Hoffman; Cameron Damgaard; Michael Slater; David H. Drewry; Matthew B. Robers; Alison D. Axtman

NEK Family Kinases: Structure, Function, and Role in Disease NEK家族激酶：结构、功能及在疾病中的作用

Biomolecules 2025, Vol. 15, Page 1406

IF4.8

2025-10-02

OAAI

Brandon M. Baker; Julia R. Boehling; Sarah Knopf; Stephanie Held; Margarite Matossian; Jorge A. Belgodere; Van T. Hoang; Bridgette M. Collins-Burow; Elizabeth C. Martin; Sean B. Lee; Matthew E. Burow; David H. Drewry; Robert H. Newman

A soft-stiff patterned bioengineering model reveals kinase pathways driving directional cell migration in pulmonary arterial hypertension 一种软-硬模式生物工程模型揭示了驱动肺动脉高压中定向细胞迁移的激酶通路

Biomater. Sci.

IF5.7

2025-09-19

OAAI

Tamanna Islam; Jacob Hooper; Xiaojun Zhang; Clarissa Garcia; Md Mahedi Hasan; David H. Drewry; Mohammad Anwar Hossain; Taslim A. Al-Hilal

NUAK kinases: signaling mechanisms and therapeutic applications NUAK激酶：信号传导机制和 therapeutic applications

Journal of Biological Chemistry

IF3.9

2025-08-05

OAAI

Nicole M. Cullen; Peter Rosston; Bakhtawar Tufail; Anne E. D’Armond; Ayushi Patel; Dara H. Khosravi; Bridgette C. Burow; Van T. Hoang; Elizabeth C. Martin; David H. Drewry; Matthew E. Burow; Suresh K. Alahari

Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors 化学蛋白质组学分析用于鉴定抗真菌激酶抑制剂的C. albicans特征

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-03-20

PREAI

Shirley, David J.; Nandakumar, Meganathan; Cabrera, Aurora; Yiu, Bonnie; Puumala, Emily; Liu, Zhongle; Robbins, Nicole; Whitesell, Luke; Smith, Jeffrey L.; Lyons, Scott; Mordant, Angie L.; Herring, Laura E.; Graves, Lee M.; Counago, Rafael M.; Drewry, David H.; Cowen, Leah E.

Convergence on CaMK4: A Key Modulator of Autism-Associated Signaling Pathways in Neurons CaMK4上的收敛: 神经元自闭症相关信号通路的关键调节剂

BIOLOGICAL PSYCHIATRY

IF9

2025-03-01

OAAI

Kaiser, Jacqueline; Risteska, Alana; Muller, Abbey G.; Sun, Haoxiong; Lei, Bethany; Nay, Kevin; Means, Anthony R.; Cousin, Margot A.; Drewry, David H.; Oakhill, Jonathan S.; Kemp, Bruce E.; Hannan, Anthony J.; Berk, Michael; Febbraio, Mark A.; Gundlach, Andrew L.; Hill-Yardin, Elisa L.; Scott, John W.

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

MOLECULES

IF4.6

2024-09-02

OAAI

Ong, Han Wee; Yang, Xuan; Smith, Jeffery L.; Taft-Benz, Sharon; Howell, Stefanie; Dickmander, Rebekah J.; Havener, Tammy M.; Sanders, Marcia K.; Brown, Jason W.; Counago, Rafael M.; Chang, Edcon; Kraemer, Andreas; Moorman, Nathaniel J.; Heise, Mark; Axtman, Alison D.; Drewry, David H.; Willson, Timothy M.

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-07-03

OAAI

Ong, Han Wee; Yang, Xuan; Smith, Jeffery L.; Dickmander, Rebekah J.; Brown, Jason W.; Havener, Tammy M.; Taft-Benz, Sharon; Howell, Stefanie; Sanders, Marcia K.; Capener, Jacob L.; Counago, Rafael M.; Chang, Edcon; Kraemer, Andreas; Moorman, Nathaniel J.; Heise, Mark; Axtman, Alison D.; Drewry, David H.; Willson, Timothy M.

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-07-03

OAAI

Bashore, Frances M.; Min, Sophia M.; Chen, Xiangrong; Howell, Stefanie; Rinderle, Caroline H.; Morel, Gabriel; Silvaroli, Josie A.; Wells, Carrow I.; Bunnell, Bruce A.; Drewry, David H.; Pabla, Navjot S.; Ultanir, Sila K.; Bullock, Alex N.; Axtman, Alison D.

Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-05-01

OAAI

Asquith, Christopher R. M.; East, Michael P.; Laitinen, Tuomo; Alamillo-Ferrer, Carla; Hartikainen, Erkka; Wells, Carrow I.; Axtman, Alison D.; Drewry, David H.; Tizzard, Graham J.; Poso, Antti; Willson, Timothy M.; Johnson, Gary L.

Illumination of understudied ciliary kinases

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2024-03-08

OAAI

Flax, Raymond G.; Rosston, Peter; Rocha, Cecilia; Anderson, Brian; Capener, Jacob L.; Durcan, Thomas M.; Drewry, David H.; Prinos, Panagiotis; Axtman, Alison D.

Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2023-11-27

OAAI

Ong, Han Wee; de Silva, Chandi; Avalani, Krisha; Kwarcinski, Frank; Mansfield, Christopher R.; Chirgwin, Michael; Truong, Anna; Derbyshire, Emily R.; Zutshi, Reena; Drewry, David H.

Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus 开源抗生素: 简单的二芳基咪唑对耐甲氧西林金黄色葡萄球菌有效

ACS INFECTIOUS DISEASES

IF3.8

2023-11-22

OAAI

Klug, Dana M.; Tse, Edwin G.; Silva, Daniel G.; Cao, Yafeng; Charman, Susan A.; Chauhan, Jyoti; Crighton, Elly; Dichiara, Maria; Drake, Chris; Drewry, David; da Silva Emery, Flavio; Ferrins, Lori; Graves, Lee; Hopkins, Emily; Kresina, Thomas A. C.; Lorente-Macias, Alvaro; Perry, Benjamin; Phipps, Richard; Quiroga, Bruno; Quotadamo, Antonio; Sabatino, Giada N.; Sama, Anthony; Schatzlein, Andreas; Simpson, Quillon J.; Steele, Jonathan; Shanu-Wilson, Julia; Sjo, Peter; Stapleton, Paul; Swain, Christopher J.; Vaideanu, Alexandra; Xie, Huanxu; Zuercher, William; Todd, Matthew H.

Fused Tetrahydroquinolines Are Interfering with Your Assay

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-10-24

OAAI

Bashore, Frances M.; Annor-Gyamfi, Joel; Du, Yuhong; Katis, Vittorio; Nwogbo, Felix; Flax, Raymond G.; Frye, Stephen V.; Pearce, Kenneth H.; Fu, Haian; Willson, Timothy M.; Drewry, David H.; Axtman, Alison D.

CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle CaMKK2不参与骨骼肌收缩刺激的AMPK激活和葡萄糖摄取

MOLECULAR METABOLISM

IF6.6

2023-09-01

OAAI

Negoita, Florentina; Addinsall, Alex B.; Hellberg, Kristina; Bringas, Conchita Fraguas; Hafen, Paul S.; Sermersheim, Tyler J.; Agerholm, Marianne; Lewis, Christopher T. A.; Ahwazi, Danial; Ling, Naomi X. Y.; Larsen, Jeppe K.; Deshmukh, Atul S.; Hossain, Mohammad A.; Oakhill, Jonathan S.; Ochala, Julien; Brault, Jeffrey J.; Sankar, Uma; Drewry, David H.; Scott, John W.; Witczak, Carol A.; Sakamoto, Kei

How many kinases are druggable? A review of our current understanding 有多少种激酶是可药的？回顾我们目前的理解

BIOCHEMICAL JOURNAL

IF4.3

2023-08-29

OAAI

Anderson, Brian; Rosston, Peter; Ong, Han Wee; Hossain, Mohammad Anwar; Davis-Gilbert, Zachary W.; Drewry, David H.

LKB1 signaling and patient survival outcomes in hepatocellular carcinoma

PHARMACOLOGICAL RESEARCH

IF10.5

2023-06-01

OAAI

Nguyen, Khoa; Hebert, Katherine; McConnell, Emily; Cullen, Nicole; Cheng, Thomas; Awoyode, Susanna; Martin, Elizabeth; Chen, Weina; Wu, Tong; Alahari, Suresh K.; Izadpanah, Reza; Collins-Burow, Bridgette M.; Lee, Sean B.; Drewry, David H.; Burow, Matthew E.

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective 发现具有神经保护作用的有效且选择性的CDKL5/GSK3化学探针

ACS CHEMICAL NEUROSCIENCE

IF3.9

2023-04-21

OAAI

Ong, Han Wee; Liang, Yi; Richardson, William; Lowry, Emily R.; Wells, Carrow I.; Chen, Xiangrong; Silvestre, Margaux; Dempster, Kelvin; Silvaroli, Josie A.; Smith, Jeffery L.; Wichterle, Hynek; Pabla, Navjot S.; Ultanir, Sila K.; Bullock, Alex N.; Drewry, David H.; Axtman, Alison D.

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

SCIENTIFIC REPORTS

IF3.9

2023-04-14

OAAI

Bashore, Frances M. M.; Marquez, Ariana B. B.; Chaikuad, Apirat; Howell, Stefanie; Dunn, Andrea S. S.; Beltran, Alvaro A. A.; Smith, Jeffery L. L.; Drewry, David H. H.; Beltran, Adriana S. S.; Axtman, Alison D. D.

研究方向