Stanley T. Crooke - Publications, H-index & Citations

Stanley T. Crooke

n-lorem foundation

94H指数

534论文数

3.2W被引数

收录论文 121

发表时间

Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy 个体化反义寡核苷酸SCN2A-related发展性癫痫脑病

Nature Medicine

IF50

2026-07-21

OAAI

Olivia Kim-McManus; Laurence Mignon; Julie Douville; He Pu; Catherine Parisien; Sarah Glass; C. Frank Bennett; Janelle Celso; Kendall Robbins; Hoameng Ung; Heather Olson; Stephen F. Kingsmore; Steven Petrou; Stanley T. Crooke; Joseph G. Gleeson; Elizabeth Berry-Kravis

Phosphorothioate antisense oligonucleotide induced innate immune activation is attenuated by tryptophan oxidation products 硫代磷酸酯反义寡核苷酸诱导的固有免疫激活被色氨酸氧化产物减弱

Nucleic Acids Research

IF13.1

2026-04-13

OAAI

Julia Pytte; Lesley Saldana; Wei Zhang; Konstantina Skourti-Stathaki; Stanley T Crooke

Establishing a commercial solution for extremely rare genetic diseases 为极其罕见的遗传疾病建立商业解决方案

Nature Biotechnology

IF41.7

2026-03-02

PREAI

Stanley T. Crooke; Andrew W. Lo

Letter: Correspondence on Damle, SS, et al. (2025) A Workflow for Transcriptome-Wide Assessment of Antisense Oligonucleotide Selectivity. Nucleic Acid Therapeutics 信函：关于Damle, SS等人（2025年）《转录组范围反义寡核苷酸选择性评估的工作流程》的通信，《核酸治疗学》

NUCLEIC ACID THERAPEUTICS

IF4.7

2025-12-01

PREAI

Crooke, Stanley T.

Splice-modulating antisense oligonucleotides targeting a pathogenic intronic variant in adult polyglucosan body disease correct mis-splicing and restore enzyme activity in patient cells 靶向成人聚葡萄糖体病中一种致病性内含子变异的剪接调控反义寡核苷酸，能够纠正错剪接并在患者细胞中恢复酶活性。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-07-22

OAAI

Thomas, Ria; Miyoshi, Emily; Akman, Hasan O.; Storz, Sophie H. R.; Goffena, Joy; Pytte, Julia; Miller, Danny E.; Skourti-Stathaki, Konstantina; Crooke, Stanley T.

Addressing the Needs of Nano-Rare Patients 满足纳米罕见患者的需求

NUCLEIC ACID THERAPEUTICS

IF4.7

2025-01-29

PREAI

Crooke, Stanley T.

Addressing the Challenges of Treating Patients with Heterozygous Gain of Function Mutations

NUCLEIC ACID THERAPEUTICS

IF4.7

2024-12-01

PREAI

Crooke, Stanley T.

Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder KIF1A-associated神经系统疾病患者的反义寡核苷酸治疗

NATURE MEDICINE

IF50

2024-08-09

PREAI

Ziegler, Alban; Carroll, Joanne; Bain, Jennifer M.; Sands, Tristan T.; Fee, Robert J.; Uher, David; Kanner, Cara H.; Montes, Jacqueline; Glass, Sarah; Douville, Julie; Mignon, Laurence; Gleeson, Joseph G.; Crooke, Stanley T.; Chung, Wendy K.

Safety and Tolerability of GalNAc3-Conjugated Antisense Drugs Compared to the Same-Sequence 2′-O-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data

NUCLEIC ACID THERAPEUTICS

IF4.7

2024-02-01

OAAI

Baker, Brenda F.; Xia, Shuting; Partridge, Wesley; Engelhardt, Jeffery A.; Tsimikas, Sotirios; Crooke, Stanley T.; Bhanot, Sanjay; Geary, Richard S.

Characterization of cooperative PS-oligo activation of human TLR9

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-09-01

OAAI

Pollak, Adam J.; Zhao, Luyi; Crooke, Stanley T.

A way forward for diagnosis of patients with extremely rare genetic mutations

NATURE BIOTECHNOLOGY

IF41.7

2023-07-17

PREAI

Crooke, Stanley T.; Kim-McManus, Olivia S.; Dalby, Kelley

Personalized antisense oligonucleotides 'for free, for life' - the n-Lorem Foundation

NATURE MEDICINE

IF50

2023-05-11

PREAI

Gleeson, Joseph G. G.; Bennett, C. Frank; Carroll, Jeffrey B. B.; Cole, Tracy; Douville, Julie; Glass, Sarah; Tekendo-Ngongang, Cedrik; Williford, Amy C. C.; Crooke, Stanley T. T.

Systematic Analysis of Chemical Modifications of Phosphorothioate Antisense Oligonucleotides that Modulate Their Innate Immune Response

NUCLEIC ACID THERAPEUTICS

IF4.7

2023-04-01

PREAI

Pollak, Adam J.; Zhao, Luyi; Crooke, Stanley T.

SIDT2 Inhibits Phosphorothioate Antisense Oligonucleotide Activity by Regulating Cellular Localization of Lysosomes

NUCLEIC ACID THERAPEUTICS

IF4.7

2023-04-01

PREAI

Zhao, Jing Crystal; Saleh, Aurian; Crooke, Stanley T.

The Combination of Mesyl-Phosphoramidate Inter-Nucleotide Linkages and 2'-O-Methyl in Selected Positions in the Antisense Oligonucleotide Enhances the Performance of RNaseH1 Active PS-ASOs

NUCLEIC ACID THERAPEUTICS

IF4.7

2022-10-01

OAAI

Zhang, Lingdi; Liang, Xue-hai; De Hoyos, Cheryl Li; Migawa, Michael; Nichols, Joshua G.; Freestone, Graeme; Tian, Jun; Seth, Punit P.; Crooke, Stanley T.

NAT10 and DDX21 Proteins Interact with RNase H1 and Affect the Performance of Phosphorothioate Oligonucleotides

NUCLEIC ACID THERAPEUTICS

IF4.7

2022-08-01

OAAI

Zhang, Lingdi; Bernardo, Karla D.; Vickers, Timothy A.; Tian, Jun; Liang, Xue-hai; Crooke, Stanley T.

Insights into innate immune activation via PS-ASO-protein-TLR9 interactions

NUCLEIC ACIDS RESEARCH

IF13.1

2022-07-15

OAAI

Pollak, Adam J.; Zhao, Luyi; Vickers, Timothy A.; Huggins, Ian J.; Liang, Xue-Hai; Crooke, Stanley T.