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A

Amy E. Baxter

University of Pennsylvania
H指数:43
被引数:1.1万

个人简介

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工作经历

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Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and role in disease

组织驻留的耗竭型和记忆型CD8+ T细胞具有不同的发生、功能及在疾病中的角色。

Nature Immunology
IF27.6
2025-12-290
PRE
Simone L. Park; Mark M. Painter; Sasikanth Manne; Victor Alcalde; Maura McLaughlin; Matthew A. Sullivan; Divij Mathew; Leonel Torres; Yinghui J. Huang; David B. Reeg; Naomi R. Douek; Trenton Campos; Max Klapholz; Maria A. Cardenas; Victoria Fang; Shin Foong Ngiow; Wumesh KC; Rishi R. Goel; Amy E. Baxter; Jennifer E. Wu; Melody Tan; Corbett T. Berry; Christoph T. Ellebrecht; Huang C. Alexander; Emily Papazian; Ying Liu; Karthik Rajasekaran; Robert M. Brody; Erica R. Thaler; Devraj Basu; Ahmed Diab; Josephine R. Giles; E. John Wherry
TET2 regulates early and late transitions in exhausted CD8+ T cell differentiation and limits CAR T cell function
SCIENCE ADVANCES
IF12.5
2024-11-150
OAAI
Dimitri, Alexander J.; Baxter, Amy E.; Chen, Gregory M.; Hopkins, Caitlin R.; Rouin, Geoffrey T.; Huang, Hua; Kong, Weimin; Holliday, Christopher H.; Wiebking, Volker; Bartoszek, Robert; Drury, Sydney; Dalton, Katherine; Koucky, Owen M.; Chen, Zeyu; Giles, Josephine R.; Dils, Alexander T.; Jung, In-Young; O'Connor, Roddy; Collins, Sierra; Everett, John K.; Amses, Kevin; Sherrill-Mix, Scott; Chandra, Aditi; Goldman, Naomi; Vahedi, Golnaz; Jadlowsky, Julie K.; Young, Regina M.; Melenhorst, Jan Joseph; Maude, Shannon L.; Levine, Bruce L.; Frey, Noelle V.; Berger, Shelley L.; Grupp, Stephan A.; Porter, David L.; Herbst, Friederike; Porteus, Matthew H.; Carty, Shannon A.; Bushman, Frederic D.; Weber, Evan W.; Wherry, E. John; Jordan, Martha S.; Fraietta, Joseph A.
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+T cells
IMMUNITY
IF26.3
2023-06-0122
OA
Baxter, Amy E.; Huang, Hua; Giles, Josephine R.; Chen, Zeyu; Wu, Jennifer E.; Drury, Sydney; Dalton, Katherine; Park, Simone L.; Torres, Leonel; Simone, Brandon W.; Klapholz, Max; Ngiow, Shin Foong; Freilich, Elizabeth; Manne, Sasikanth; Alcalde, Victor; Ekshyyan, Viktoriya; Berger, Shelley L.; Shi, Junwei; Jordan, Martha S.; Wherry, John
Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome (vol 12, e01777-21, 2021)
MBIO
IF4.7
2022-10-262
OAAI
Merenstein, Carter; Liang, Guanxiang; Whiteside, Samantha A.; Cobian-Guemes, Ana G.; Merlino, Madeline S.; Taylor, Louis J.; Glascock, Abigail; Bittinger, Kyle; Tanes, Ceylan; Graham-Wooten, Jevon; Khatib, Layla A.; Fitzgerald, Ayannah S.; Reddy, Shantan; Baxter, Amy E.; Giles, Josephine R.; Oldridge, Derek A.; Meyer, Nuala J.; Wherry, E. John; McGinniss, John E.; Bushman, Frederic D.; Collman, Ronald G.
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

通过时间单细胞转录组学和表观遗传学揭示效应，记忆和耗尽的CD8 T细胞中的共享和独特的生物回路

NATURE IMMUNOLOGY
IF27.6
2022-10-2193
OA
Giles, Josephine R.; Ngiow, Shin Foong; Manne, Sasikanth; Baxter, Amy E.; Khan, Omar; Wang, Ping; Staupe, Ryan; Abdel-Hakeem, Mohamed S.; Huang, Hua; Mathew, Divij; Painter, Mark M.; Wu, Jennifer E.; Huang, Yinghui Jane; Goel, Rishi R.; Yan, Patrick K.; Karakousis, Giorgos C.; Xu, Xiaowei; Mitchell, Tara C.; Huang, Alexander C.; Wherry, E. John
Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

HIV特异性CD4 T细胞上的免疫检查点表达及其对其阻断的反应取决于谱系和功能

EBIOMEDICINE
IF10.8
2022-10-018
OAAI
Brunet-Ratnasingham, Elsa; Morou, Antigoni; Dube, Mathieu; Niessl, Julia; Baxter, Amy E.; Tastet, Olivier; Brassard, Nathalie; Ortega-Delgado, Gloria; Charlebois, Roxanne; Freeman, Gordon J.; Tremblay, Cecile; Routy, Jean-Pierre; Kaufmann, Daniel E.
Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19
FRONTIERS IN IMMUNOLOGY
IF5.9
2022-03-0325
OAAI
Apostolidis, Sokratis A.; Sarkar, Amrita; Giannini, Heather M.; Goel, Rishi R.; Mathew, Divij; Suzuki, Aae; Baxter, Amy E.; Greenplate, Allison R.; Alanio, Cecile; Abdel-Hakeem, Mohamed; Oldridge, Derek A.; Giles, Josephine R.; Wu, Jennifer E.; Chen, Zeyu; Huang, Yinghui Jane; Belman, Jonathan; Pattekar, Ajinkya; Manne, Sasikanth; Kuthuru, Oliva; Dougherty, Jeanette; Weiderhold, Brittany; Weisman, Ariel R.; Ittner, Caroline A. G.; Gouma, Sigrid; Dunbar, Debora; Frank, Ian; Huang, Alexander C.; Vella, Laura A.; Reilly, John P.; Hensley, Scott E.; Rauova, Lubica; Zhao, Liang; Meyer, Nuala J.; Poncz, Mortimer; Abrams, Charles S.; Wherry, E. John
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
IMMUNITY
IF26.3
2022-03-0161
OA
Giles, Josephine R.; Manne, Sasikanth; Freilich, Elizabeth; Oldridge, Derek A.; Baxter, Amy E.; George, Sangeeth; Chen, Zeyu; Huang, Hua; Chilukuri, Lakshmi; Carberry, Mary; Giles, Lydia; Weng, Nan-Ping P.; Young, Regina M.; June, Carl H.; Schuchter, Lynn M.; Amaravadi, Ravi K.; Xu, Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Huang, Alexander C.; Shi, Junwei; Wherry, E. John
Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction
NATURE COMMUNICATIONS
IF15.7
2021-12-1041
OAAI
Diorio, Caroline; Shraim, Rawan; Vella, Laura A.; Giles, Josephine R.; Baxter, Amy E.; Oldridge, Derek A.; Canna, Scott W.; Henrickson, Sarah E.; McNerney, Kevin O.; Balamuth, Frances; Burudpakdee, Chakkapong; Lee, Jessica; Leng, Tomas; Farrel, Alvin; Lambert, Michele P.; Sullivan, Kathleen E.; Wherry, E. John; Teachey, David T.; Bassiri, Hamid; Behrens, Edward M.
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination
IMMUNITY
IF26.3
2021-09-01324
OAAI
Painter, Mark M.; Mathew, Divij; Goel, Rishi R.; Apostolidis, Sokratis A.; Pattekar, Ajinkya; Kuthuru, Oliva; Baxter, Amy E.; Herati, Ramin S.; Oldridge, Derek A.; Gouma, Sigrid; Hicks, Philip; Dysinger, Sarah; Lundgreen, Kendall A.; Kuri-Cervantes, Leticia; Adamski, Sharon; Hicks, Amanda; Korte, Scott; Giles, Josephine R.; Weirick, Madison E.; McAllister, Christopher M.; Dougherty, Jeanette; Long, Sherea; D'Andrea, Kurt; Hamilton, Jacob T.; Betts, Michael R.; Bates, Paul; Hensley, Scott E.; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Greenplate, Allison R.; Wherry, E. John
Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome
MBIO
IF4.7
2021-08-3181
OAAI
Merenstein, Carter; Liang, Guanxiang; Whiteside, Samantha A.; Cobian-Guemes, Ana G.; Merlino, Madeline S.; Taylor, Louis J.; Glascock, Abigail; Bittinger, Kyle; Tanes, Ceylan; Graham-Wooten, Jevon; Khatib, Layla A.; Fitzgerald, Ayannah S.; Reddy, Shantan; Baxter, Amy E.; Giles, Josephine R.; Oldridge, Derek A.; Meyer, Nuala J.; Wherry, E. John; McGinniss, John E.; Bushman, Frederic D.; Collman, Ronald G.
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

CD8 T细胞有助于COVID-19和血液系统癌症患者的生存

NATURE MEDICINE
IF50
2021-05-20309
OAAI
Bange, Erin M.; Han, Nicholas A.; Wileyto, Paul; Kim, Justin Y.; Gouma, Sigrid; Robinson, James; Greenplate, Allison R.; Hwee, Madeline A.; Porterfield, Florence; Owoyemi, Olutosin; Naik, Karan; Zheng, Cathy; Galantino, Michael; Weisman, Ariel R.; Ittner, Caroline A. G.; Kugler, Emily M.; Baxter, Amy E.; Oniyide, Olutwatosin; Agyekum, Roseline S.; Dunn, Thomas G.; Jones, Tiffanie K.; Giannini, Heather M.; Weirick, Madison E.; McAllister, Christopher M.; Babady, N. Esther; Kumar, Anita; Widman, Adam J.; DeWolf, Susan; Boutemine, Sawsan R.; Roberts, Charlotte; Budzik, Krista R.; Tollett, Susan; Wright, Carla; Perloff, Tara; Sun, Lova; Mathew, Divij; Giles, Josephine R.; Oldridge, Derek A.; Wu, Jennifer E.; Alanio, Cecile; Adamski, Sharon; Garfall, Alfred L.; Vella, Laura A.; Kerr, Samuel J.; Cohen, Justine, V; Oyer, Randall A.; Massa, Ryan; Maillard, Ivan P.; Maxwell, Kara N.; Reilly, John P.; Maslak, Peter G.; Vonderheide, Robert H.; Wolchok, Jedd D.; Hensley, Scott E.; Wherry, E. John; Meyer, Nuala J.; DeMichele, Angela M.; Vardhana, Santosha A.; Mamtani, Ronac; Huang, Alexander C.
Distinct antibody and memory B cell responses in SARS-CoV-2 naive and recovered individuals after mRNA vaccination
SCIENCE IMMUNOLOGY
IF16.3
2021-04-02485
OAAI
Goel, Rishi R.; Apostolidis, Sokratis A.; Painter, Mark M.; Mathew, Divij; Pattekar, Ajinkya; Kuthuru, Oliva; Gouma, Sigrid; Hicks, Philip; Meng, Wenzhao; Rosenfeld, Aaron M.; Dysinger, Sarah; Lundgreen, Kendall A.; Kuri-Cervantes, Leticia; Adamski, Sharon; Hicks, Amanda; Korte, Scott; Oldridge, Derek A.; Baxter, Amy E.; Giles, Josephine R.; Weirick, Madison E.; McAllister, Christopher M.; Dougherty, Jeanette; Long, Sherea; D'Andrea, Kurt; Hamilton, Jacob T.; Betts, Michael R.; Prak, Eline T. Luning; Bates, Paul; Hensley, Scott E.; Greenplate, Allison R.; Wherry, E. John
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19
SCIENCE IMMUNOLOGY
IF16.3
2021-03-04127
OAAI
Vella, Laura A.; Giles, Josephine R.; Baxter, Amy E.; Oldridge, Derek A.; Diorio, Caroline; Kuri-Cervantes, Leticia; Alanio, Cecile; Pampena, M. Betina; Wu, Jennifer E.; Chen, Zeyu; Huang, Yinghui Jane; Anderson, Elizabeth M.; Gouma, Sigrid; McNerney, Kevin O.; Chase, Julie; Burudpakdee, Chakkapong; Lee, Jessica H.; Apostolidis, Sokratis A.; Huang, Alexander C.; Mathew, Divij; Kuthuru, Oliva; Goodwin, Eileen C.; Weirick, Madison E.; Bolton, Marcus J.; Arevalo, Claudia P.; Ramos, Andre; Jasen, C. J.; Conrey, Peyton E.; Sayed, Samir; Giannini, Heather M.; D'Andrea, Kurt; Meyer, Nuala J.; Behrens, Edward M.; Bassiri, Hamid; Hensley, Scott E.; Henrickson, Sarah E.; Teachey, David T.; Betts, Michael R.; Wherry, E. John

研究方向

暂未获取到该数据
J
Josephine R. Giles
H 指数:37论文数:101被引数:1.3万
E
E. John Wherry
H 指数:142论文数:644被引数:10.9万
D
Daniel E. Kaufmann
H 指数:69论文数:282被引数:2.1万
D
Derek A. Oldridge
H 指数:39论文数:164被引数:1.0万
D
Divij Mathew
H 指数:36论文数:105被引数:9,521
J
Jennifer E. Wu
H 指数:27论文数:43被引数:8,721
S
Sasikanth Manne
H 指数:39论文数:111被引数:1.2万
L
Laura A. Vella
H 指数:36论文数:91被引数:8,197
陈则宇 封面图
陈则宇
H 指数:32论文数:126被引数:8,408
A
Allison R. Greenplate
H 指数:41论文数:126被引数:1.1万