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Christopher E. Hart

Eli Lilly and Company

16H-index
42Paper Count
1.6KCitation Count
Published Papers 17
Publication Date
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Longitudinal characterization of clinical, developmental, and behavioral phenotypes in 101 children and adults with FOXG1 syndrome
errJournal of Neurodevelopmental Disorders
IF4
err2025-10-26
err0
errOAAI
errElise Brimble; Pam Ventola; Elizabeth Blomenberg; Kelsey Frahlich; Kopika Kuhathaas; Christopher E. Hart; Nadia Bahi-Buisson; Heather E. Olson; Eric D. Marsh; Gai Ayalon
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errSave
A Workflow for Transcriptome-Wide Assessment of Antisense Oligonucleotide Selectivity
errnucleic acid therapeutics
IF4.7
err2025-09-29
err0
PREAI
errSagar S. Damle; Andy Watt; Steven Kuntz; Amanda Crutchfield; Emma Carlborg; Judy Webb; Clare Quirk; Dorde Relic; Scott Donovan; Christopher E. Hart; Frank Rigo
errShare
errSave
GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells
errMOLECULAR THERAPY-NUCLEIC ACIDS
IF0
err2023-06-01
err4
errOAAI
errMcMahon, Moira A.; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Bui, Huynh-Hoa; Hart, Christopher; Damle, Sagar; Courtney, Margo; Baughn, Michael W.; Cleveland, Don W.; Bennett, Frank
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errSave
Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung
errAMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
IF5.3
err2020-07-01
err25
PREAI
errCarrer, Michele; Crosby, Jeff R.; Sun, Guizhen; Zhao, Chenguang; Damle, Sagar S.; Kuntz, Steven G.; Monia, Brett P.; Hart, Christopher E.; Grossman, Tamar R.
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errSave
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice
errJCI INSIGHT
IF6.1
err2019-06-20
err74
errOAAI
errAghajan, Mariam; Booten, Sheri L.; Althage, Magnus; Hart, Christopher E.; Ericsson, Anette; Maxvall, Ingela; Ochaba, Joseph; Menschik-Lundin, Angela; Hartleib, Judith; Kuntz, Steven; Gattis, Danielle; Ahlstrom, Christine; Watt, Andrew T.; Engelhardt, Jeffery A.; Monia, Brett P.; Magnone, Maria Chiara; Guo, Shuling
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errSave
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index
errNATURE BIOTECHNOLOGY
IF41.7
err2019-04-29
err220
PREAI
errShen, Wen; De Hoyos, Cheryl L.; Migawa, Michael T.; Vickers, Timothy A.; Sun, Hong; Low, Audrey; Bell, Thomas A., III; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Hart, Christopher E.; Bell, Melanie; Riney, Stan; Murray, Susan F.; Greenlee, Sarah; Crooke, Rosanne M.; Liang, Xue-hai; Seth, Punit P.; Crooke, Stanley T.
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errSave
A modular analysis of microglia gene expression, insights into the aged phenotype
errBMC GENOMICS
IF3.7
err2019-02-28
err27
errOAAI
errCho, Christine E.; Damle, Sagar S.; Wancewicz, Edward V.; Mukhopadhyay, Swagatam; Hart, Christopher E.; Mazur, Curt; Swayze, Eric E.; Kamme, Fredrik
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errSave
HELM Software for Biopolymers
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2017-05-19
err13
PREAI
errMilton, Jeff; Zhang, Tianhong; Bellamy, Claire; Swayze, Eric; Hart, Christopher; Weisser, Markus; Hecht, Sabrina; Rotstein, Sergio
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errSave
Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers
errMOLECULAR THERAPY
IF12
err2016-10-01
err92
errOAAI
errCrooke, Stanley T.; Baker, Brenda F.; Kwoh, T. Jesse; Cheng, Wei; Schulz, Dan J.; Xia, Shuting; Salgado, Nelson; Bui, Huynh-Hoa; Hart, Christopher E.; Burel, Sebastien A.; Younis, Husam S.; Geary, Richard S.; Henry, Scott P.; Bhanot, Sanjay
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errSave
The Cell Wall Arabinose-Deficient Arabidopsis thaliana Mutant murus5 Encodes a Defective Allele of REVERSIBLY GLYCOSYLATED POLYPEPTIDE2
errPLANT PHYSIOLOGY
IF6.9
err2016-05-23
err10
errOAAI
errDugard, Christopher K.; Mertz, Rachel A.; Rayon, Catherine; Mercadante, Davide; Hart, Christopher; Benatti, Matheus R.; Olek, Anna T.; SanMiguel, Phillip J.; Cooper, Bruce R.; Reiter, Wolf-Dieter; McCann, Maureen C.; Carpita, Nicholas C.
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errSave
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function
errNUCLEIC ACIDS RESEARCH
IF13.1
err2016-04-29
err94
errOAAI
errLima, Walt F.; Murray, Heather M.; Damle, Sagar S.; Hart, Christopher E.; Hung, Gene; De Hoyos, Cheryl Li; Liang, Xue-Hai; Crooke, Stanley T.
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errSave
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
errNUCLEIC ACIDS RESEARCH
IF13.1
err2015-11-08
err156
errOAAI
errBurel, Sebastien A.; Hart, Christopher E.; Cauntay, Patrick; Hsiao, Jill; Machemer, Todd; Katz, Melanie; Watt, Andy; Bui, Huynh-hoa; Younis, Husam; Sabripour, Mahyar; Freier, Susan M.; Hung, Gene; Dan, Amy; Prakash, T. P.; Seth, Punit P.; Swayze, Eric E.; Bennett, C. Frank; Crooke, Stanley T.; Henry, Scott P.
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errSave
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages
errNUCLEIC ACIDS RESEARCH
IF13.1
err2014-11-14
err151
errOAAI
errWan, W. Brad; Migawa, Michael T.; Vasquez, Guillermo; Murray, Heather M.; Nichols, Josh G.; Gaus, Hans; Berdeja, Andres; Lee, Sam; Hart, Christopher E.; Lima, Walt F.; Swayze, Eric E.; Seth, Punit P.
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errSave
Genome-wide identification and characterization of replication origins by deep sequencing
errGENOME BIOLOGY
IF9.4
err2012-04-24
err88
errOAAI
errXu, Jia; Yanagisawa, Yoshimi; Tsankov, Alexander M.; Hart, Christopher; Aoki, Keita; Kommajosyula, Naveen; Steinmann, Kathleen E.; Bochicchio, James; Russ, Carsten; Regev, Aviv; Rando, Oliver J.; Nusbaum, Chad; Niki, Hironori; Milos, Patrice; Weng, Zhiping; Rhind, Nicholas
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errSave
Tobacco carcinogen-induced transformation of HBECs is associated with chromatin-mediated reprogramming of the epigenome
errCANCER RESEARCH
IF16.6
err2011-04-01
err0
PREAI
errTellez, Carmen S.; Juri, Daniel E.; Van Neste, Leander; Hart, Christopher; Liu, Yushi; Do, Kieu; Picchi, Maria A.; Belinsky, Steven A.
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errSave
A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data
errNUCLEIC ACIDS RESEARCH
IF13.1
err2005-04-28
err11
errOAAI
errHart, CE; Sharenbroich, L; Bornstein, BJ; Trout, D; King, B; Mjolsness, E; Wold, BJ
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errSave
Clustering analysis of microarray gene expression data by splitting algorithm
errJOURNAL OF PARALLEL AND DISTRIBUTED COMPUTING
IF4
err2003-07-01
err8
PREAI
errWang, RY; Scharenbroich, L; Hart, C; Wold, B; Mjolsness, E
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errSave

Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
A
Aviv Regev
H-index: 208 · Papers: 965
D
Don W. Cleveland
H-index: 165 · Papers: 525
Zhiping Weng cover
Zhiping Weng (Zhiping Weng)
H-index: 119 · Papers: 538
C
C. Frank Bennett
H-index: 100 · Papers: 331
S
Stanley T. Crooke
H-index: 94 · Papers: 534
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