Not logged inNovel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability
Lagardere, Prisca; Mustiere, Romain; Amanzougaghene, Nadia; Hutter, Sebastien; Casanova, Marion; Franetich, Jean-Francois; Tajeri, Shahin; Malzert-Freon, Aurelie; Corvaisier, Sophie; Since, Marc; Azas, Nadine; Vanelle, Patrice; Verhaeghe, Pierre; Primas, Nicolas; Mazier, Dominique; Masurier, Nicolas; Lisowski, Vincent .png)
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SaveNew antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stabilityLagardere, Prisca; Mustiere, Romain; Amanzougaghene, Nadia; Hutter, Sebastien; Casanova, Marion; Franetich, Jean-Francois; Tajeri, Shahin; Malzert-Freon, Aurelie; Corvaisier, Sophie; Azas, Nadine; Vanelle, Patrice; Verhaeghe, Pierre; Primas, Nicolas; Mazier, Dominique; Masurier, Nicolas; Lisowski, Vincent Share Save Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategyMustiere, Romain; Lagardere, Prisca; Hutter, Sebastien; Dell'Orco, Viviana; Amanzougaghene, Nadia; Tajeri, Shahin; Franetich, Jean-Francois; Corvaisier, Sophie; Since, Marc; Malzert-Freon, Aurelie; Masurier, Nicolas; Lisowski, Vincent; Verhaeghe, Pierre; Mazier, Dominique; Azas, Nadine; Vanelle, Patrice; Primas, Nicolas Share Save 4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial DerivativesLagardere, Prisca; Mustiere, Romain; Amanzougaghene, Nadia; Hutter, Sebastien; Franetich, Jean-Francois; Azas, Nadine; Vanelle, Patrice; Verhaeghe, Pierre; Primas, Nicolas; Mazier, Dominique; Masurier, Nicolas; Lisowski, Vincent Share Save Share Save Share Save A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant ParasitesBosson-Vanga, Henriette; Primas, Nicolas; Franetich, Jean-Francois; Lavazec, Catherine; Gomez, Lina; Ashraf, Kutub; Tefit, Maurel; Soulard, Valerie; Dereuddre-Bosquet, Nathalie; Le Grand, Roger; Donnette, Melanie; Mustiere, Romain; Amanzougaghene, Nadia; Tajeri, Shahin; Suzanne, Peggy; Malzert-Freon, Aurelie; Rault, Sylvain; Vanelle, Patrice; Hutter, Sebastien; Cohen, Anita; Snounou, Georges; Roques, Pierre; Azas, Nadine; Lagardere, Prisca; Lisowski, Vincent; Masurier, Nicolas; Nguyen, Michel; Paloque, Lucie; Benoit-Vical, Francoise; Verhaeghe, Pierre; Mazier, Dominique Share Save Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease TreatmentSeguy, Line; Guyon, Lena; Maurel, Manon; Verdie, Pascal; Davis, Audrey; Corvaisier, Sophie; Lisowski, Vincent; Dallemagne, Patrick; Groo, Anne-Claire; Malzert-Freon, Aurelie Share Save Share Save Share Save Share Save Imidazopyridine-fused [1,3]-diazepinones part 2: Structure-activity relationships and antiproliferative activity against melanoma cellsBellet, Virginie; Lichon, Laure; Arama, Dominique P.; Gallud, Audrey; Lisowski, Vincent; Maillard, Ludovic T.; Garcia, Marcel; Martinez, Jean; Masurier, Nicolas Share Save Structure-Activity Relationships of JMV4463, a Vectorized CathepsinD Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based VectorVezenkov, Lubomir L.; Sanchez, Clement A.; Bellet, Virginie; Martin, Vincent; Maynadier, Marie; Bettache, Nadir; Lisowski, Vincent; Martinez, Jean; Garcia, Marcel; Amblard, Muriel; Hernandez, Jean-Francois Share Save Share Save Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological EvaluationLegrand, Baptiste; Mathieu, Loic; Lebrun, Aurelien; Andriamanarivo, Soahary; Lisowski, Vincent; Masurier, Nicolas; Zirah, Severine; Kang, Young Kee; Martinez, Jean; Maillard, Ludovic T. Share Save Imidazopyridine-fused [1,3] -diazepinones: Synthesis and antiproliferative activityGallud, Audrey; Vaillant, Ophelie; Maillard, Ludovic T.; Arama, Dominique P.; Dubois, Joelle; Maynadier, Marie; Lisowski, Vincent; Garcia, Marcel; Martinez, Jean; Masurier, Nicolas Share Save Helical Oligomers of Thiazole-Based -Amino Acids: Synthesis and Structural StudiesMathieu, Loic; Legrand, Baptiste; Deng, Cheng; Vezenkov, Lubomir; Wenger, Emmanuel; Didierjean, Claude; Amblard, Muriel; Averlant-Petit, Marie-Christine; Masurier, Nicolas; Lisowski, Vincent; Martinez, Jean; Maillard, Ludovic T. Share Save Share Save Selective C-Acylation of 2-Aminoimidazo[1,2-a]pyridine: Application to the Synthesis of Imidazopyridine-Fused [1,3]DiazepinonesMasurier, Nicolas; Aruta, Roberta; Gaumet, Vincent; Denoyelle, Severine; Moreau, Emmanuel; Lisowski, Vincent; Martinez, Jean; Maillard, Ludovic T. Share Save Chemical Optimization of New Ligands of the Low-Density Lipoprotein Receptor as Potential Vectors for Central Nervous System TargetingMalcor, Jean-Daniel; Payrot, Nadine; David, Marion; Faucon, Aude; Abouzid, Karima; Jacquot, Guillaume; Floquet, Nicolas; Debarbieux, Franck; Rougon, Genevieve; Martinez, Jean; Khrestchatisky, Michel; Vlieghe, Patrick; Lisowski, Vincent Share Save 
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