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Targeting Neutrophil-Mediated Inflammation: Identification of Pyrazolidinone Carboxamide Derivatives as Potent Selective Inhibitors of Formyl Peptide Receptor 1 (FPR1)-Activated Neutrophils Abdel-Halim, M; Wagdy, RA; Salah, M; Wang, YH; Cheng, TP; Lee, YR; Chen, YC; Mandour, YM; Abadi, AH; Engel, M; Hwang, TL Share Save
From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds Keddis, Parthiena M.; Tu, Tuong-Khanh My; Scherer, Hugo; Kany, Andreas M.; Hafez, Donia E.; Darwish, Sarah S.; Abadi, Ashraf H.; Hirsch, Anna K. H.; Engel, Matthias; Hamed, Mostafa M.; Horng, Jim-Tong; Abdel-Halim, Mohammad Share Save
Design, synthesis, and structure-activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors Faouzi, Abdelfattah; Arnaud, Alexandre; Halle, Francois; Roussel, Jean; Aymard, Mandy; Denavit, Vincent; Do, Cong Viet; Mularoni, Angelique; Salah, Mohamed; ElHady, Ahmed; Pham, Thanh-Nhat; Bancet, Alexandre; Le Borgne, Marc; Terreux, Raphael; Barret, Roland; Engel, Matthias; Lomberget, Thierry Share Save
Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold Khalifa, Hend; ElHady, Ahmed K.; Liu, Ting; Elgaher, Walid A. M.; Filhol-Cochet, Odile; Cochet, Claude; Abadi, Ashraf H.; Hamed, Mostafa M.; Abdel-Halim, Mohammad; Engel, Matthias Share Save
Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways Abdel-Halim, Mohammad; El-Gamil, Dalia S.; Hammam, Mennatallah A.; El-Shazly, Mohamed; Wang, Yi-Hsuan; Kung, Po-Hsiung; Chen, Yu-Cheng; Korinek, Michal; Abadi, Ashraf H.; Engel, Matthias; Hwang, Tsong-Long Share Save
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Molecular insights into the regulatory landscape of PKC-related kinase-2 (PRK2/PKN2) using targeted small compounds Gross, Lissy Z. F.; Winkel, Angelika F.; Galceran, Facundo; Schulze, Joerg O.; Froehner, Wolfgang; Caemmerer, Simon; Zeuzem, Stefan; Engel, Matthias; Leroux, Alejandro E.; Biondi, Ricardo M. Share Save
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity Abd El-Rahman, Yara A.; Chen, Po-Jen; ElHady, Ahmed K.; Chen, Shun-Hua; Lin, Hsin-Chieh; El-Gamil, Dalia S.; Aboushady, Youssef; Abadi, Ashraf H.; Engel, Matthias; Abdel-Halim, Mohammad Share Save
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity Al-Saad, Omar M.; Gabr, Moustafa; Darwish, Sarah S.; Rullo, Mariagrazia; Pisani, Leonardo; Miniero, Daniela Valeria; Liuzzi, Grazia Maria; Kany, Andreas M.; Hirsch, Anna K. H.; Abadi, Ashraf H.; Engel, Matthias; Catto, Marco; Abdel-Halim, Mohammad Share Save
Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity Wagdy, Reem A.; Abutaleb, Nader S.; Fathalla, Reem K.; Elgammal, Yehia; Weck, Stefanie; Pal, Rusha; Fischer, Patrick D.; Ducho, Christian; Abadi, Ashraf H.; Seleem, Mohamed N.; Engel, Matthias; Abdel-Halim, Mohammad Share Save
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Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA Fathalla, Reem K.; Froehner, Wolfgang; Bader, Chantal D.; Fischer, Patrick D.; Dahlem, Charlotte; Chatterjee, Deep; Mathea, Sebastian; Kiemer, Alexandra K.; Arthanari, Haribabu; Muller, Rolf; Abdel-Halim, Mohammad; Ducho, Christian; Engel, Matthias Share Save
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