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Selective, Non-nucleotidic Radiotracer for P2Y12 Receptors: Design, Synthesis, Characterization, and Imaging of Brain Slices Al-Hroub, Haneen; Al Musawi, Hashem Ali M.; Abdelrahman, Aliaa; Corbel, Margot; Petit, Fanny; Aksiyote, Gunes; Beau, Fabrice; Jan, Caroline; Bemelmans, Alexis-Pierre; Van Camp, Nadja; Peyronneau, Marie-Anne; Winkeler, Alexandra Share Save
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Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist (May, 10.1007/s11302-024-10005-2, 2024) Nagel, Jessica; Tormakangas, Olli; Kuokkanen, Katja; El-Tayeb, Ali; Messinger, Josef; Abdelrahman, Aliaa; Bous, Christiane; Schiedel, Anke C.; Mueller, Christa E. Share Save
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Thermal proteome profiling identifies the membrane- bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin Corrales, Marjorie A. Carnero; Zinken, Sarah; Konstantinidis, Georgios; Rafehi, Muhammad; Abdelrahman, Aliaa; Wu, Yao-Wen; Janning, Petra; Mueller, Christa E.; Laraia, Luca; Waldmann, Herbert Share Save
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Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists Tian, Maoqun; Abdelrahman, Aliaa; Baqi, Younis; Fuentes, Eduardo; Azazna, Djamil; Spanier, Claudia; Densborn, Sabrina; Hinz, Sonja; Schmid, Ralf; Mueller, Christa E. Share Save
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors Kuschak, Markus; Namasivayam, Vigneshwaran; Rafehi, Muhammad; Voss, Jan H.; Garg, Jaspal; Schlegel, Jonathan G.; Abdelrahman, Aliaa; Kehraus, Stefan; Reher, Raphael; Kueppers, Jim; Sylvester, Katharina; Hinz, Sonja; Matthey, Michaela; Wenzel, Daniela; Fleischmann, Bernd K.; Pfeifer, Alexander; Inoue, Asuka; Guetschow, Michael; Koenig, Gabriele M.; Mueller, Christa E. Share Save
2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes Bhattarai, Sanjay; Pippel, Jan; Scaletti, Emma; Idris, Riham; Freundlieb, Marianne; Rolshoven, Georg; Renn, Christian; Lee, Sang-Yong; Abdelrahman, Aliaa; Zimmermann, Herbert; El-Tayeb, Ali; Mueller, Christa E.; Straeter, Norbert Share Save
Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs Scheeff, Stephan; Riviere, Solenne; Ruiz, Johal; Abdelrahman, Aliaa; Schulz-Fincke, Anna-Christina; Koese, Meryem; Tiburcy, Felix; Wieczorek, Helmut; Guetschow, Michael; Mueller, Christa E.; Menche, Dirk Share Save
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X-Ray Co-Crystal Structure Guides the Way to Subnanomolar Competitive Ecto-5′-Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy Bhattarai, Sanjay; Pippel, Jan; Meyer, Anne; Freundlieb, Marianne; Schmies, Constanze; Abdelrahman, Aliaa; Fiene, Amelie; Lee, Sang-Yong; Zimmermann, Herbert; El-Tayeb, Ali; Yegutkin, Gennady G.; Straeter, Norbert; Mueller, Christa E. Share Save
Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists Dal Ben, Diego; Buccioni, Michela; Lambertucci, Catia; Marucci, Gabriella; Spinaci, Andrea; Marchenkova, Anna; Abdelrahman, Aliaa; Nistri, Andrea; Mueller, Christa E.; Volpini, Rosaria Share Save
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17 Baqi, Younis; Pillaiyar, Thanigaimalai; Abdelrahman, Aliaa; Kaufmann, Olesja; Aishaibani, Samer; Rafehi, Muhammad; Ghasimi, Saman; Akkari, Rhalid; Ritter, Kirsten; Simon, Katharina; Spinrath, Andreas; Kostenis, Evi; Zhao, Qiang; Koese, Meryem; Namasivayam, Vigneshwaran; Mueller, Christa E. Share Save
Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells Kwak, Seung-Hwa; Shin, Seungheon; Lee, Ji-Hyun; Shim, Jin-Kyoung; Kim, Minjeong; Lee, So-Deok; Lee, Aram; Bae, Jinsu; Park, Jin-Hee; Abdelrahman, Aliaa; Mueller, Christa E.; Cho, Steve K.; Kang, Seok-Gu; Bae, Myung Ae; Yang, Jung Yoon; Ko, Hyojin; Goddard, William A., III; Kim, Yong-Chul Share Save
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Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies Abdelrahman, Aliaa; Namasivayam, Vigneshwaran; Hinz, Sonja; Schiedel, Anke C.; Koese, Meryem; Burton, Maggi; El-Tayeb, Ali; Gillard, Michel; Bajorath, Juergen; de Ryck, Marc; Mueller, Christa E. Share Save
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