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William A. Denny

University of Auckland

84H-index
868Paper Count
2.6WCitation Count
Published Papers 246
Publication Date
New Antitubercular Pretomanid Analogues as Potent Payloads in Polymeric Micelles: Leveraging Zebrafish Assays to Accelerate Lead Optimisation
err2026-01-30
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errAndrew M. Thompson; Nils-Jørgen K. Dal; Francesca Boldrin; Noelia Alonso-Rodriguez; Gabriela Schäfer; Kerstin Johann; Martin Speth; Laura Cioetto-Mazzabò; Adrián Pál; Jana Korduláková; Matthias Barz; Federico Fenaroli; William A. Denny; Gareth Griffiths
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Advancing the antituberculosis activity of nitropicolinic acids and amides
err2025-10-29
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errOAAI
errAndrew M. Thompson; Chen-Yi Cheung; Matthew B. McNeil; Ashley C. Campbell; Monika Záhorszká; Jana Korduláková; Giovanni Stelitano; Deborah Recchia; Maria Rosalia Pasca; Baojie Wan; Shahebraj Khan; Dejan S. Nikolic; Gauri S. Shetye; Scott G. Franzblau; William A. Denny; Gregory M. Cook; Kurt L. Krause
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ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
err2024-11-28
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errOAAI
errGong, Grace Q.; Masson, Glenn R.; Lee, Woo-Jeong; Dickson, James M. J.; Kendall, Jackie D.; Rathinaswamy, Manoj K.; Buchanan, Christina M.; Middleditch, Martin; Owen, Brady M.; Spicer, Julie A.; Rewcastle, Gordon W.; Denny, William A.; Burke, John E.; Shepherd, Peter R.; Williams, Roger L.; Flanagan, Jack U.
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Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate
err2024-01-11
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errCooper, Elizabeth; Oyagawa, Caitlin R. M.; Johnson, Rebecca; Choi, Peter J.; Foliaki, Jena Macapagal; Correia, Jason; Schweder, Patrick; Heppner, Peter; Mee, Edward; Turner, Clinton; Faull, Richard; Denny, William A.; Dragunow, Mike; Jose, Jiney; Park, Thomas I-H.
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RETRACTION: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation (Retraction of Vol 69, Pg 4277, 2009)
err2023-12-15
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errDatta, Jharna; Ghoshal, Kalpana; Denny, William A.; Gamage, Swarna A.; Brooke, Darby G.; Phiasivongsa, Pasit; Redkar, Sanjeev; Jacob, Samson T.
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Synthesis and Anti-Mycobacterium tuberculosis Activity of Imidazo[2,1-b][1,3]oxazine Derivatives against Multidrug-Resistant Strains
err2023-04-21
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errOAAI
errFernandes, Guilherme F. S.; Manieri, Karyn F.; Bonjorno, Andressa F.; Campos, Debora L.; Ribeiro, Camila M.; Demarqui, Fernanda M.; Ruiz, Daniel A. G.; Nascimento-Junior, Nailton M.; Denny, William A.; Thompson, Andrew M.; Pavan, Fernando R.; Dos Santos, Jean L.
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Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug-carrier molecule for the treatment of glioblastoma
err2022-11-29
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errCooper, Elizabeth; Choi, Peter J.; Hwang, Kihwan; Nam, Kyung M.; Kim, Chae-Yong; Shaban, Tina; Schweder, Patrick; Mee, Edward; Correia, Jason; Turner, Clinton; Faull, Richard L. M.; Denny, William A.; Noguchi, Katsuya; Dragunow, Mike; Jose, Jiney; Park, Thomas I-H.
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Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue
err2022-10-14
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errOAAI
errCooper, Elizabeth; Woolf, Zoe; Swanson, Molly E., V; Correia, Jason; Schweder, Patrick; Mee, Edward; Heppner, Peter; Turner, Clinton; Faull, Richard L. M.; Scotter, Emma L.; Denny, William A.; Choi, Peter J.; Dragunow, Mike; Jose, Jiney; Park, Thomas I-H
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Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines
err2022-09-08
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errSutherland, Hamish S.; Choi, Peter J.; Lu, Guo-Liang; Giddens, Anna C.; Tong, Amy S. T.; Franzblau, Scott G.; Cooper, Christopher B.; Palmer, Brian D.; Denny, William A.
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The development of a potent, tumour-specific heptamethine cyanine dye-palbociclib conjugate with novel mechanisms of action for the treatment of glioblastoma
err2022-09-05
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errCooper, E. A.; Choi, P. J.; Schweder, P.; Correia, J.; Turner, C.; Faull, R.; Denny, W. A.; Dragunow, M.; Jose, J.; Park, T., I
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Tuberculosis Drug Discovery: Challenges and New Horizons
err2022-05-25
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errFernandes, Guilherme F. S.; Thompson, Andrew M.; Castagnolo, Daniele; Denny, William A.; Dos Santos, Jean L.
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Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis
err2022-02-01
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errSutherland, Hamish S. S.; Lu, Guo-Liang; Tong, Amy S. T. G.; Conole, Daniel M.; Franzblau, Scott G. U.; Upton, Anna B.; Lotlikar, Manisha U. D.; Cooper, Christopher B. J.; Palmer, Brian D. A.; Choi, Peter J.; Denny, William A.
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Conjugation of Palbociclib with MHI-148 Has an Increased Cytotoxic Effect for Breast Cancer Cells and an Altered Mechanism of Action
err2022-01-27
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errOAAI
errChoi, Peter Jaein; Tomek, Petr; Tercel, Moana; Reynisson, Johannes; Park, Thomas In Hyeup; Cooper, Elizabeth Alexandra; Denny, William Alexander; Jose, Jiney; Leung, Euphemia
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Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs
err2021-06-23
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errLeung, Euphemia; Patel, Jinal; Hollywood, Jennifer A.; Zafar, Ayesha; Tomek, Petr; Barker, David; Pilkington, Lisa I.; van Rensburg, Michelle; Langley, Ries J.; Helsby, Nuala A.; Squire, Christopher J.; Baguley, Bruce C.; Denny, William A.; Reynisson, Johannes; Leung, Ivanhoe K. H.
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Simplifying Submission Requirements for the Journal of Medicinal Chemistry
err2021-06-15
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PREAI
errLindsley, Craig W.; Barrow, James; Chibale, Kelly; Bolognesi, Maria Laura; Conway, Stuart; Denny, William; Ding, Ke; Laufer, Stefan; Lai, Luhua; Liu, Hong; Neamati, Nouri; Suzuki, Takayoshi; Meanwell, Nicholas; Young, Wendy
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The Use of Heptamethine Cyanine Dyes as Drug-Conjugate Systems in the Treatment of Primary and Metastatic Brain Tumors
err2021-06-01
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errOAAI
errCooper, Elizabeth; Choi, Peter J.; Denny, William A.; Jose, Jiney; Dragunow, Mike; Park, Thomas I-H
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Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility
err2021-01-21
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errThompson, Andrew M.; O'Connor, Patrick D.; Yardley, Vanessa; Maes, Louis; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.
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Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal
err2021-01-01
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errThompson, Andrew M.; O'Connor, Patrick D.; Marshall, Andrew J.; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.
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