Thomas M. Carlile - Publications, H-index & Citations

Back

Thomas M. Carlile

biogen inc.

17H-index

36Paper Count

2.5KCitation Count

Published Papers 11

Publication Date

Spatial transcriptomics reveal heterogeneous cell‒cell interactions among brain regions in cuprizone model consistent with multiple sclerosis lesions

Frontiers in Bioinformatics

IF3.9

2026-08-20

OAAI

HT Hui-Hsin Tsai †; SP Sarbottam Piya †; JW Jing Wang; JZ Jing Zhu; WH Wenxing Hu; AR Andrew R. Gehrke; SC Shaolong Cao; AJ Amanda J. Guise; SJ Su Jing Chan; MS Mark Sheehan; JC Jenhwa Chu; ZO Zhengyu Ouyang; MR Matthew Ryals; ML Michelle Lee; WW Wanli Wang; EZ Edward Zhao; PC Patrick Cullen; RC Ravi Challa; EM Eric Marshall; WZ Wanyong Zeng; YJ Yea Jin Kaeser-Woo; CE Chris Ehrenfels; LJ Luke Jandreski; HM Helen McLaughlin; TM Thomas M. Carlile; JG Jake Gagnon; TL Taylor L. Reynolds; ML Mingyao Li; KL Kejie Li; BZ Baohong Zhang

Save

Discovery and Optimization of Thienopyrazine RNA-Splicing Modulators for the Treatment of Huntington’s Disease

Journal of Medicinal Chemistry

IF6.8

2026-03-17

PREAI

Chaofan Xu; Neeta Abraham; Nupur Bansal; Philippe N. Bolduc; Patrick Cullen; Thomas M. Carlile; Yirui Chen; Colin K. Choi; Rachelle Driscoll; Eric Stefan; Christina M. Gallo; Zhen Gao; Catherine L. Guardado; Guilherme Guimaraes; James Harvey; Sarah Huff; Dann Huh; Jessica Hurt; Melissa M. Kemp; Kwang Soo Lee; Joon Lee; Mukesh Lulla; Soumya Negi; Marta Nevalainen; Emily A. Peterson; Thomas J. Purgett; Joseph C. Santoro; Daniel R. Smith; Andreas Weihofen; Zain Yousaf; Magnus Pfaffenbach

Save

Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE

Nature Methods

IF32.1

2025-09-15

OAAI

Amelia Schroeder; Melanie L. Loth; Chunyu Luo; Sicong Yao; Hanying Yan; Daiwei Zhang; Sarbottam Piya; Edward Plowey; Wenxing Hu; Jean R. Clemenceau; Inyeop Jang; Minji Kim; Isabel Barnfather; Su Jing Chan; Taylor L. Reynolds; Thomas Carlile; Patrick Cullen; Ji-Youn Sung; Hui-Hsin Tsai; Jeong Hwan Park; Tae Hyun Hwang; Baohong Zhang; Mingyao Li

Save

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2023-12-01

OAAI

Chen, Shukkwan K.; Hawley, Zachary C. E.; Zavodszky, Maria I.; Hana, Sam; Ferretti, Daniel; Grubor, Branka; Hawes, Michael; Xu, Shanqin; Hamann, Stefan; Marsh, Galina; Cullen, Patrick; Challa, Ravi; Carlile, Thomas M.; Zhang, Hang; Lee, Wan-Hung; Peralta, Andrea; Clarner, Pete; Wei, Cong; Koszka, Kathryn; Gao, Feng; Lo, Shih-Ching

Save

MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response

BRAIN

IF11.7

2021-06-19

OAAI

Pellerin, Kathryn; Rubino, Stephen J.; Burns, Jeremy C.; Smith, Benjamin A.; Mccarl, Christie-Ann; Zhu, Jing; Jandreski, Luke; Cullen, Patrick; Carlile, Thomas M.; Li, Angela; Rebollar, Jorge Vera; Sybulski, Jennifer; Reynolds, Taylor L.; Zhang, Baohong; Basile, Rebecca; Tang, Hao; Harp, Chelsea Parker; Pellerin, Alex; Silbereis, John; Franchimont, Nathalie; Cahir-McFarland, Ellen; Ransohoff, Richard M.; Cameron, Thomas O.; Mingueneau, Michael

Save

Benchmarking and optimization of a high-throughput sequencing based method for transgene sequence variant analysis in biotherapeutic cell line development

BIOTECHNOLOGY JOURNAL

IF3.1

2021-06-03

PREAI

Groot, Joost; Zhou, Yizhou; Marshall, Eric; Cullen, Patrick; Carlile, Thomas; Lin, Dongdong; Xu, Chong-Feng; Crisafulli, Justin; Sun, Chao; Casey, Fergal; Zhang, Baohong; Alves, Christina

Save

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2020-12-21

OAAI

Delbridge, Alex R. D.; Huh, Dann; Brickelmaier, Margot; Burns, Jeremy C.; Roberts, Chris; Challa, Ravi; Raymond, Naideline; Cullen, Patrick; Carlile, Thomas M.; Ennis, Katelin A.; Liu, Mei; Sun, Chao; Allaire, Normand E.; Foos, Marianna; Tsai, Hui-Hsin; Franchimont, Nathalie; Ransohoff, Richard M.; Butts, Cherie; Mingueneau, Michael

Save

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis

NATURE MEDICINE

IF50

2019-12-05

OAAI

Lafaille, Fabien G.; Harschnitz, Oliver; Lee, Yoon Seung; Zhang, Peng; Hasek, Mary L.; Kerner, Gaspard; Itan, Yuval; Ewaleifoh, Osefame; Rapaport, Franck; Carlile, Thomas M.; Carter-Timofte, Madalina E.; Paquet, Dominik; Dobbs, Kerry; Zimmer, Bastian; Gao, Daxing; Rojas-Duran, Maria F.; Kwart, Dylan; Rattina, Vimel; Ciancanelli, Michael J.; McAlpine, Jessica L.; Lorenzo, Lazaro; Boucherit, Soraya; Rozenberg, Flore; Halwani, Rabih; Henry, Benoit; Amenzoui, Naima; Alsum, Zobaida; Marques, Laura; Church, Joseph A.; Al-Muhsen, Saleh; Tardieu, Marc; Bousfiha, Ahmed Aziz; Paludan, Soren R.; Mogensen, Trine Hyrup; Quintana-Murci, Lluis; Tessier-Lavigne, Marc; Smith, Gregory A.; Notarangelo, Luigi D.; Studer, Lorenz; Gilbert, Wendy; Abel, Laurent; Casanova, Jean-Laurent; Zhang, Shen-Ying

Save

mRNA structure determines modification by pseudouridine synthase 1

NATURE CHEMICAL BIOLOGY

IF13.7

2019-09-02

116

OAAI

Carlile, Thomas M.; Martinez, Nicole M.; Schaening, Cassandra; Su, Amanda; Bell, Tristan A.; Zinshteyn, Boris; Gilbert, Wendy, V

Save

Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2016-08-10

154

OAAI

Stanley, Susan E.; Gable, Dustin L.; Wagner, Christa L.; Carlile, Thomas M.; Hanumanthu, Vidya Sagar; Podlevsky, Joshua D.; Khalil, Sara E.; DeZern, Amy E.; Rojas-Duran, Maria F.; Applegate, Carolyn D.; Alder, Jonathan K.; Parry, Erin M.; Gilbert, Wendy V.; Armanios, Mary

Save

Aneuploid yeast strains exhibit defects in cell growth and passage through START

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2013-05-01

OAAI

Thorburn, Rebecca R.; Gonzalez, Christian; Brar, Gloria A.; Christen, Stefan; Carlile, Thomas M.; Ingolia, Nicholas T.; Sauer, Uwe; Weissman, Jonathan S.; Amon, Angelika

Save

Research Directions