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Y

Ye Tian

soochow university - china
H指数:27
被引数:2,017

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Design, synthesis, and biological evaluation of piperidinyl-substituted [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potential anti-HIV-1 agents with reduced cytotoxicity

哌啶基取代的 [1,2，4] 三唑并 [1，5-a] 嘧啶衍生物作为具有降低的细胞毒性的潜在anti-HIV-1剂的设计，合成和生物学评估

CHEMICAL BIOLOGY & DRUG DESIGN
IF3.3
2020-08-0326
OAAI
Huang, Boshi; Kang, Dongwei; Tian, Ye; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng; Liu, Xinyong
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-02-0571
PREAI
Huang, Boshi; Chen, Wenmin; Zhao, Tong; Li, Zhenyu; Jiang, Xiangyi; Ginex, Tiziana; Vilchez, David; Luque, Francisco Javier; Kang, Dongwei; Gao, Ping; Zhang, Jian; Tian, Ye; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng; Liu, Xinyong
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-10-2642
OAAI
Zhang, Jian; Murugan, Natarajan Arul; Tian, Ye; Bertagnin, Chiara; Fang, Zengjun; Kang, Dongwei; Kong, Xiujie; Jia, Haiyong; Sun, Zhuosen; Jia, Ruifang; Gao, Ping; Poongayanam, Vasanthanathan; Loregian, Arianna; Xu, Wenfang; Ma, Xiuli; Ding, Xiao; Huang, Bing; Zhan, Peng; Liu, Xinyong
Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-05-1590
PREAI
Kang, Dongwei; Fang, Zengjun; Huang, Boshi; Lu, Xueyi; Zhang, Heng; Xu, Haoran; Huo, Zhipeng; Zhou, Zhongxia; Yu, Zhao; Meng, Qing; Wu, Gaochan; Ding, Xiao; Tian, Ye; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng; Liu, Xinyong

研究方向

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刘
刘新泳
H 指数:54论文数:427被引数:1.1万
展
展鹏
H 指数:51论文数:376被引数:1.0万
C
Christophe Pannecouque
H 指数:71论文数:757被引数:2.0万
E
Erik De Clercq
H 指数:162论文数:3,980被引数:14.4万
X
Xingwei Wang
H 指数:0论文数:2被引数:0
N
Nan Wu
H 指数:27论文数:114被引数:3,066
X
Xiaotian Zou
H 指数:18论文数:55被引数:1,257
王文辉 封面图
王文辉
H 指数:38论文数:161被引数:8,687
D
Dongwei Kang
H 指数:40论文数:190被引数:4,824
B
Boshi Huang
H 指数:27论文数:81被引数:2,179