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L

Lin Sun

chongqing southeast hospital
H指数:18
被引数:2,503

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Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators

带有Quinazolin-4-one支架的新型苯丙氨酸衍生物作为有效的HIV衣壳调节剂的发现，晶体学研究和机理研究

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-12-063
OA
Xu, Shujing; Sun, Lin; Barnett, Michael; Zhang, Xujie; Ding, Dang; Gattu, Anushka; Shi, Dazhou; Taka, Jamie R. H.; Shen, Wenli; Jiang, Xiangyi; Cocklin, Simon; De Clercq, Erik; Pannecouque, Christophe; Goldstone, David C.; Liu, Xinyong; Dick, Alexej; Zhan, Peng
From design to biological mechanism evaluation of phenylalanine-bearing HIV-1 capsid inhibitors targeting a vital assembly interface

靶向重要组装界面的含苯丙氨酸HIV-1衣壳抑制剂的设计到生物学机制评估

CHINESE CHEMICAL LETTERS
IF8.9
2023-03-0111
PRE
Xu, Shujing; Sun, Lin; Zalloum, Waleed A.; Zhang, Xujie; Huang, Tianguang; Ding, Dang; Tao, Yucen; Zhao, Fabao; Gao, Shenghua; Kang, Dongwei; De Clercq, Erik; Pannecouque, Christophe; Dick, Alexej; Cocklin, Simon; Liu, Xinyong; Zhan, Peng
Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2022-01-0123
OAAI
Xu, Shujing; Sun, Lin; Dick, Alexej; Zalloum, Waleed A.; Huang, Tianguang; Meuser, Megan E.; Zhang, Xujie; Tao, Yucen; Cherukupalli, Srinivasulu; Ding, Dang; Ding, Xiao; Gao, Shenghua; Jiang, Xiangyi; Kang, Dongwei; De Clercq, Erik; Pannecouque, Christophe; Cocklin, Simon; Liu, Xinyong; Zhan, Peng

研究方向

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刘
刘新泳
H 指数:54论文数:427被引数:1.1万
展
展鹏
H 指数:51论文数:376被引数:1.0万
S
Shujing Xu
H 指数:22论文数:140被引数:1,713
C
Christophe Pannecouque
H 指数:71论文数:757被引数:2.0万
E
Erik De Clercq
H 指数:162论文数:3,980被引数:14.4万
D
Dongwei Kang
H 指数:40论文数:190被引数:4,819
X
Xujie Zhang
H 指数:17论文数:62被引数:1,318
高平 封面图
高平
H 指数:61论文数:292被引数:2.2万
A
Alexej Dick
H 指数:17论文数:47被引数:1,227
T
Tianguang Huang
H 指数:9论文数:16被引数:368