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A

Alice L. Rodriguez

Vanderbilt University School of Medicine
H指数:36
被引数:4,135

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工作经历

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荣誉奖项

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Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons

发现VU6077564：一种选择性M1拮抗剂，可促进成年感觉神经元轴突生长

ACS Chemical Neuroscience
IF3.9
2026-07-070
OA
Tomayo I. Berida; Cayden J. Dodd; Joshua C. Wilkinson; Darrell R. Smith; Sichen Chang; Christopher C. Presley; Li Peng; Snehal Sant; Srinivasan Krishnan; Irene Zagol-Ikapitte; Katherine J. Watson; Analisa Thompson Gray; Alice L. Rodriguez; Hyekyung P. Cho; Carrie K. Jones; Olivier Boutaud; Colleen M. Niswender; Darren W. Engers; Paul Fernyhough; Craig W. Lindsley; Elizabeth S. Childress
Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-; Antipsychotic-; and Procognitive-like Activity in Rodents

发现VU6066098：一种选择性中枢神经系统可穿透的mGlu2 NAM，在啮齿动物中表现出强效的抗抑郁、抗精神病和促认知样活性

ACS Chemical Neuroscience
IF3.9
2026-06-230
OA
Jeremy S. Coleman; Rory A. Capstick; Sichen Chang; Derek J. Rios; Michael Bubser; Analisa D. Thompson Gray; Irene Zagol-Ikapitte; Srinivasan Krishnan; Hyekyung P. Cho; Alice L. Rodriguez; Colleen M. Niswender; Olivier Boutaud; Georgina Perez Garcia; Gregory A. Elder; Darren W. Engers; Carrie K. Jones; Craig W. Lindsley
Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent; Selective; and CNS-Penetrant Agonists for the Cannabinoid Receptor 2
Journal of Medicinal Chemistry
IF6.8
2026-02-050
OA
Daniel H. Haymer; Renn A. Duncan; Alice L. Rodriguez; Allie Han; Richard J. Lindsay; N. Kithmini Wijesiri; Analisa Thompson Gray; Srinivasan Krishnan; Aidong Qi; Benjamin P. Brown; Olivier Boutaud; Darren W. Engers; Carrie K. Jones; Colleen M. Niswender; Craig W. Lindsley; Aaron M. Bender
Discovery of VU6025733 (AG06827): A Highly Selective; Orally Bioavailable; and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy
ACS Chemical Neuroscience
IF3.9
2026-01-250
OAAI
Alison R. Gregro; Charlotte Park; Madeline F. Long; Logan A. Baker; Katrina A. Bollinger; Anna E. Ringuette; Li Peng; Vincent B. Luscombe; Natasha B. Billard; Alice L. Rodriguez; Colleen M. Niswender; Weimin Peng; Jonathan W. Dickerson; Jerri M. Rook; Jordan O’Neill; Sichen Chang; Harrie C. M. Boonen; Thomas Jensen; Morten S. Thomsen; Thomas M. Bridges; Olivier Boutaud; P. Jeffrey Conn; Darren W. Engers; Craig W. Lindsley; Kayla J. Temple
Discovery of 7-(Pyridin-3-yl)thieno[3; 2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5
ACS Chemical Neuroscience
IF3.9
2026-01-250
OAAI
Scott H. Henderson; Anna E. Ringuette; David L. Whomble; Rory A. Capstick; Alexa E. Richardson; Mallory A. Maurer; Natasha B. Billard; Xia Lei; Joshua C. Wilkinson; Sri H. Kethanapalli; Hyekyung P. Cho; Alice L. Rodriguez; Colleen M. Niswender; Weimin Peng; Jerri M. Rook; Sichen Chang; Anna L. Blobaum; Olivier Boutaud; Andrew S. Felts; P. Jeffrey Conn; Craig W. Lindsley; Kayla J. Temple
Characterization of Novel and Known Activators of Cannabinoid Receptor Subtype 2 Reveals Mixed Pharmacology That Differentiates Mycophenolate Mofetil and GW-842,166X from MDA7

新型和已知大麻素受体2型亚型激活剂的表征揭示了一种混合药理学，该药理学区分了霉酚酸吗啉酯和GW-842,166X与MDA7。

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
2025-05-210
OA
Rodriguez, Alice L.; Qi, Aidong; Han, Allie; Kling, Haley E.; Quitalig, Marc C.; Bender, Aaron M.; Barbaro, Lisa; Whomble, David; Lindsley, Craig W.; Niswender, Colleen M.
Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2025-04-010
OAAI
Crocker, Katherine E.; Henderson, Scott H.; Capstick, Rory A.; Whomble, David L.; Bender, Aaron M.; Felts, Andrew S.; Han, Changho; Engers, Julie L.; Billard, Natasha B.; Maurer, Mallory A.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; O'Neill, Jordan; Watson, Katherine J.; Chang, Sichen; Blobaum, Anna L.; Boutaud, Olivier; Peng, Weimin; Rook, Jerri M.; Conn, P. Jeffrey; Lindsley, Craig W.; Temple, Kayla J.
Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-12-110
OAAI
Poslunsey, Michael S.; Wood, Michael R.; Han, Changho; Stauffer, Shaun R.; Panarese, Joseph D.; Melancon, Bruce J.; Engers, Julie L.; Dickerson, Jonathan W.; Peng, Weimin; Noetzel, Meredith J.; Cho, Hyekyung P.; Rodriguez, Alice L.; Hopkins, Corey R.; Morrison, Ryan; Crouch, Rachel D.; Bridges, Thomas M.; Blobaum, Anna L.; Boutaud, Olivier; Daniels, J. Scott; Kates, Michael J.; Castelhano, Arlindo; Rook, Jerri M.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.
Discovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-11-180
OAAI
Childress, Elizabeth S.; Capstick, Rory A.; Crocker, Katherine E.; Ledyard, Miranda L.; Bender, Aaron M.; Maurer, Mallory A.; Billard, Natasha B.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; Peng, Weimin; Rook, Jerri M.; Chang, Sichen; Blobaum, Anna L.; Boutaud, Olivier; Thompson Gray, Analisa; Jones, Carrie K.; Conn, P. Jeffrey; Felts, Andrew S.; Lindsley, Craig W.; Temple, Kayla J.
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-09-240
OAAI
Engers, Julie L.; Baker, Logan A.; Chang, Sichen; Luscombe, Vincent B.; Rodriguez, Alice L.; Niswender, Colleen M.; Cho, Hyekyung P.; Bubser, Michael; Gray, Analisa Thompson; Jones, Carrie K.; Peng, Weimin; Rook, Jerri M.; Bridges, Thomas M.; Boutaud, Olivier; Conn, P. Jeffrey; Engers, Darren W.; Lindsley, Craig W.; Temple, Kayla J.
Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-08-282
OAAI
Engers, Julie L.; Bollinger, Katrina A.; Capstick, Rory A.; Long, Madeline F.; Bender, Aaron M.; Dickerson, Jonathan W.; Peng, Weimin; Presley, Christopher C.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; Moran, Sean P.; Xiang, Zixiu; Blobaum, Anna L.; Boutaud, Olivier; Rook, Jerri M.; Engers, Darren W.; Conn, P. Jeffrey; Lindsley, Craig W.
Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-08-060
OAAI
Li, Jinming; Orsi, Douglas L.; Engers, Julie L.; Long, Madeline F.; Capstick, Rory A.; Maurer, Mallory A.; Presley, Christopher C.; Vinson, Paige N.; Rodriguez, Alice L.; Han, Allie; Cho, Hyekyung P.; Chang, Sichen; Jackson, Megan; Bubser, Michael; Blobaum, Anna L.; Boutaud, Olivier; Nader, Michael A.; Niswender, Colleen M.; Conn, P. Jeffrey; Jones, Carrie K.; Lindsley, Craig W.; Han, Changho

研究方向

暂未获取到该数据
C
Craig W. Lindsley
H 指数:86论文数:1,460被引数:3.0万
C
Colleen M. Niswender
H 指数:55论文数:406被引数:1.2万
P
P. Jeffrey Conn
H 指数:97论文数:684被引数:3.7万
C
Carrie K. Jones
H 指数:53论文数:271被引数:8,553
A
Anna L. Blobaum
H 指数:34论文数:140被引数:3,405
D
Darren W. Engers
H 指数:29论文数:122被引数:2,215
J
Julie L. Engers
H 指数:18论文数:171被引数:933
S
Sichen Chang
H 指数:18论文数:86被引数:827
H
Hyekyung P. Cho
H 指数:28论文数:134被引数:2,702
O
Olivier Boutaud
H 指数:38论文数:170被引数:4,178