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J

Julie L. Engers

Vanderbilt University School of Medicine
H指数:18
被引数:933

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery of VU6052254: A Novel; Potent M1 Positive Allosteric Modulator

VU6052254的发现：一种新型的强效M1正向别构调节剂

ACS Chemical Neuroscience
IF3.9
2025-11-260
OAAI
Julie L. Engers; Joseph D. Bungard; Christopher C. Presley; Irene Zagol-Ikapitte; Katherine J. Watson; Sichen Chang; Colin O’Carroll; P. Markus Dey; Ethan S. Burstein; Jonathan W. Dickerson; Analisa Thompson Gray; Michael Bubser; Jerri M. Rook; Hyekyung P. Cho; Valerie M. Kramlinger; Olivier Boutaud; Carrie K. Jones; P. Jeffrey Conn; Darren W. Engers; Craig W. Lindsley
Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2025-04-010
OAAI
Crocker, Katherine E.; Henderson, Scott H.; Capstick, Rory A.; Whomble, David L.; Bender, Aaron M.; Felts, Andrew S.; Han, Changho; Engers, Julie L.; Billard, Natasha B.; Maurer, Mallory A.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; O'Neill, Jordan; Watson, Katherine J.; Chang, Sichen; Blobaum, Anna L.; Boutaud, Olivier; Peng, Weimin; Rook, Jerri M.; Conn, P. Jeffrey; Lindsley, Craig W.; Temple, Kayla J.
Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-12-110
OAAI
Poslunsey, Michael S.; Wood, Michael R.; Han, Changho; Stauffer, Shaun R.; Panarese, Joseph D.; Melancon, Bruce J.; Engers, Julie L.; Dickerson, Jonathan W.; Peng, Weimin; Noetzel, Meredith J.; Cho, Hyekyung P.; Rodriguez, Alice L.; Hopkins, Corey R.; Morrison, Ryan; Crouch, Rachel D.; Bridges, Thomas M.; Blobaum, Anna L.; Boutaud, Olivier; Daniels, J. Scott; Kates, Michael J.; Castelhano, Arlindo; Rook, Jerri M.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.
Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-09-240
OAAI
Engers, Julie L.; Baker, Logan A.; Chang, Sichen; Luscombe, Vincent B.; Rodriguez, Alice L.; Niswender, Colleen M.; Cho, Hyekyung P.; Bubser, Michael; Gray, Analisa Thompson; Jones, Carrie K.; Peng, Weimin; Rook, Jerri M.; Bridges, Thomas M.; Boutaud, Olivier; Conn, P. Jeffrey; Engers, Darren W.; Lindsley, Craig W.; Temple, Kayla J.
Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-08-282
OAAI
Engers, Julie L.; Bollinger, Katrina A.; Capstick, Rory A.; Long, Madeline F.; Bender, Aaron M.; Dickerson, Jonathan W.; Peng, Weimin; Presley, Christopher C.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; Moran, Sean P.; Xiang, Zixiu; Blobaum, Anna L.; Boutaud, Olivier; Rook, Jerri M.; Engers, Darren W.; Conn, P. Jeffrey; Lindsley, Craig W.
Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-08-060
OAAI
Li, Jinming; Orsi, Douglas L.; Engers, Julie L.; Long, Madeline F.; Capstick, Rory A.; Maurer, Mallory A.; Presley, Christopher C.; Vinson, Paige N.; Rodriguez, Alice L.; Han, Allie; Cho, Hyekyung P.; Chang, Sichen; Jackson, Megan; Bubser, Michael; Blobaum, Anna L.; Boutaud, Olivier; Nader, Michael A.; Niswender, Colleen M.; Conn, P. Jeffrey; Jones, Carrie K.; Lindsley, Craig W.; Han, Changho
Discovery of VU6028418: A Highly Selective and Orally Bioavailable M4 Muscarinic Acetylcholine Receptor Antagonist
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-08-029
OA
Spock, Matthew; Carter, Trever R.; Bollinger, Katrina A.; Han, Changho; Baker, Logan A.; Rodriguez, Alice L.; Peng, Li; Dickerson, Jonathan W.; Qi, Aidong; Rook, Jerri M.; O'Neill, Jordan C.; Watson, Katherine J.; Chang, Sichen; Bridges, Thomas M.; Engers, Julie L.; Engers, Darren W.; Niswender, Colleen M.; Conn, P. Jeffrey; Lindsley, Craig W.; Bender, Aaron M.
Discovery of VU2957 (Valiglurax): An mGlu4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2018-10-1620
OAAI
Panarese, Joseph D.; Engers, Darren W.; Wu, Yong-Jin; Bronson, Joanne J.; Macor, John E.; Chun, Aspen; Rodriguez, Alice L.; Felts, Andrew S.; Engers, Julie L.; Loch, Matthew T.; Emmitte, Kyle A.; Castelhano, Arlindo L.; Kates, Michael J.; Nader, Michael A.; Jones, Carrie K.; Blobaurn, Anna L.; Conn, P. Jeffrey; Niswender, Colleen M.; Hopkins, Corey R.; Lindsley, Craig W.
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1H-Pyrazolo[4,3-b]pyridin-3-yl)amino)-benzo[d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu4)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-09-2422
PREAI
Bollinger, Sean R.; Engers, Darren W.; Panarese, Joseph D.; West, Mary; Engers, Julie L.; Loch, Matthew T.; Rodriguez, Alice L.; Blobaum, Anna L.; Jones, Carrie K.; Gray, Analisa Thompson; Conn, P. Jeffrey; Lindsley, Craig W.; Niswender, Colleen M.; Hopkins, Corey R.
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M1 Positive Allosteric Modulators

发现三环三唑并和咪唑并吡啶内酰胺作为M1正变构调节剂

ACS CHEMICAL NEUROSCIENCE
IF3.9
2018-08-075
OAAI
Engers, Julie L.; Bender, Aaron M.; Kalbfleisch, Jacob J.; Cho, Hyekyung P.; Lingenfelter, Kaelyn S.; Luscombe, Vincent B.; Han, Changho; Melancon, Bruce J.; Blobaum, Anna L.; Dickerson, Jonathan W.; Rook, Jerri M.; Niswender, Colleen M.; Emmitte, Kyle A.; Conn, P. Jeffrey; Lindsley, Craig W.

研究方向

暂未获取到该数据
C
Craig W. Lindsley
H 指数:86论文数:1,460被引数:3.0万
P
P. Jeffrey Conn
H 指数:97论文数:684被引数:3.7万
C
Colleen M. Niswender
H 指数:55论文数:406被引数:1.2万
A
Alice L. Rodriguez
H 指数:36论文数:164被引数:4,135
D
Darren W. Engers
H 指数:29论文数:122被引数:2,215
S
Sichen Chang
H 指数:18论文数:86被引数:827
A
Anna L. Blobaum
H 指数:34论文数:140被引数:3,405
C
Carrie K. Jones
H 指数:53论文数:271被引数:8,553
H
Hyekyung P. Cho
H 指数:28论文数:134被引数:2,702
O
Olivier Boutaud
H 指数:38论文数:170被引数:4,178