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杨

杨浩 (Hao Yang)

Ningxia Medical University副教授，硕士生导师
H指数:12
被引数:544

个人简介

"杨浩，男，博士，副教授，硕士生导师。2014年毕业于河北科技大学化学与制药工程学院，获得理学学士学位；2018年获得宁夏医科大学医学硕士学位；2022年获得中山大学理学博士学位；2022年9月-至今任宁夏医科大学副教授，硕士生导师。作为项目负责人主持国家级项目1项，部、省、市级项目4项；近年来，在Advanced Science,Journal of Medicinal Chemistry,European Journal of Medicinal Chemistry, Bioorganic Chemistry, Bioorganic & Medicinal Chemistry Letters, ChemMedChem, Organic & Biomolecular Chemistry等国际知名期刊发表高水平论文20余篇；申请专利6项。"

教育背景

  • 2022.01 – 2022.12

    中山大学 理学博士

  • 2018.01 – 2018.12

    宁夏医科大学 医学硕士

  • 2014.01 – 2014.12

    河北科技大学化学与制药工程学院 理学学士

工作经历

  • 2022.09 – 至今

    宁夏医科大学

    副教授，硕士生导师

荣誉奖项

  1. 宁夏青年科技托举人才
Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4-b]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer

6H-苯并咪唑[1′,2′:1,2]吡啶[3,4-b]吲哚衍生物的设计、合成及生物评价：作为TDP1抑制剂的强效协同剂，与拓扑替康联合抗宫颈癌

Journal of Medicinal Chemistry
IF6.8
2026-04-010
PRE
Zeng, Huang; Qiu, Bo; Yang, Jiunlong; Xie, Yuman; Huang, Hui; Zhang, Shengyuan; Nie, Hua; Wang, Nan; Huang, Zeyong; Wu, Lingfeng; Liu, Jiayao; Zheng, Xuerou; Zhuang, Yuanbei; Yang, Hao
Synthesis and biological evaluation of phenanthridine derivatives as dual-target inhibitors of DNA topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1), and potential antitumor agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2026-01-210
PRE
Gao, Jian-Mei; Xie, Huilong; Wang, Zi-Qiang; Huang, Yu; Ouyang, Yifan; Su, Yan; Chao, Nan; Yan, Wenbo; Yuan, Hui; Zhou, Junxun; Zhang, Mei-Mei; He, Jiaxin; Hong, Zhou; Yang, Jiunlong; Fan, Yanru; Bai, Chang-Cai; Zhang, Yu; Zeng, Huang; Yang, Hao
Gridization-Driven Mesoscale Self-Assembly of Conjugated Nanopolymers into Luminescence-Anisotropic Photonic Crystals

网格化驱动的共轭纳米聚合物的介观尺度自组装成发光各向异性光子晶体

ADVANCED MATERIALS
IF26.8
2022-02-0327
PRE
Lin, Dongqing; Liu, Jin'an; Zhang, He; Qian, Yue; Yang, Hao; Liu, Lihui; Ren, Ang; Zhao, Yongsheng; Yu, Xiang; Wei, Ying; Hu, Shu; Li, Lianjie; Li, Shifeng; Sheng, Chuanxiang; Zhang, Wenhua; Chen, Shufen; Shen, Jianping; Liu, Huifang; Feng, Quanyou; Wang, Shasha; Xie, Linghai; Huang, Wei
Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

甲氧基-，亚甲基二氧基-，羟基-和卤代取代的二苯蒽环酮衍生物作为DNA拓扑异构酶IB (TOP1) 和酪胺酰-DNA磷酸二酯酶1 (TDP1) 抑制剂的合成及其对耐药癌症的生物活性

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-05-1917
OAAI
Hu, De-Xuan; Tang, Wen-Lin; Zhang, Yu; Yang, Hao; Wang, Wenjie; Agama, Keli; Pommier, Yves; An, Lin-Kun
Discovery of a potent TDP1 inhibitor through machine learning-driven predictive modeling combined with structure-based virtual screening and experimental validation

通过机器学习驱动的预测建模、基于结构的虚拟筛选与实验验证相结合发现一种高效的TDP1抑制剂

RSC Advances
IF4.6
0
PRE
Huang Zeng Corresponding Author; Manyi Zhang; Bo Qiu; Shengyuan Zhang; Jiayao Liu; Xiaodong Luo; Lingfeng Wu; Huasong Xie; Ming Zhai; Jiunlong Yang; Hao Yang; Hua Nie Corresponding Author; Nan Wang Corresponding Author

研究方向

一：调控功能性蛋白质的小分子抑制剂的发现与机制研究二：小分子荧光探针的开发及其在肿瘤早期诊断中的应用
安林坤 封面图
安林坤
H 指数:23论文数:103被引数:1,585
Y
Yu Zhang
H 指数:20论文数:84被引数:980
Y
Yifan Ouyang
H 指数:10论文数:57被引数:252
F
Fang‐Ting Wang
H 指数:4论文数:9被引数:45
王
王文杰
H 指数:39论文数:203被引数:6,192

Yves Pommier
H 指数:138论文数:2,041被引数:7.9万
K
Keli Agama
H 指数:41论文数:150被引数:4,083
H
Hua Nie
H 指数:8论文数:23被引数:158
侯
侯廷军
H 指数:92论文数:697被引数:3.9万
W
Weitao Fu
H 指数:21论文数:46被引数:1,434