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A

Alessio Lodola

university of parma

41H指数
180论文数
4.8K被引数
收录论文 108
发表时间
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The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors稀有胆汁酸异石胆酸（IALCA）是EphA2拮抗剂，可避免FXR和TGR5受体。
errBiochemical Pharmacology
IF5.6
err2026-02-13
err0
errOAAI
errAndrea Blesio; Carmine Giorgio; Francesca Romana Ferrari; Stefano Sala; Lisa Flammini; Ilaria Zanotti; Daniela Passeri; Antimo Gioiello; Lorenzo Sarcone; Riccardo Castelli; Kun Karnchanapandh; Federica Vacondio; Lorenzo Tagliazucchi; Laura Scalvini; Marco Mor; Alessio Lodola; Massimiliano Tognolini
err分享
err收藏
New Vanillyl-capped HDAC inhibitors exhibit anti-tumor efficacy in neuroblastoma and glioblastoma cells新型香草酰基封端的HDAC抑制剂在神经母细胞瘤和胶质母细胞瘤细胞中表现出抗肿瘤功效
errBioorganic Chemistry
IF4.7
err2025-10-14
err0
errOAAI
errIlaria Cursaro; Luca Frattaruolo; Laura Scalvini; Chiara Contri; Alessia Bichicchi; Nicola Tardiolo; Valeria Tudino; Sara Rossi; Eugenia Nicol Manti; Martina Cappello; Chiara Papulino; Emilia Maellaro; Paola Marcolongo; Rosaria Benedetti; Lucia Altucci; Katia Varani; Marco Mor; Maria Frosini; Fabrizio Vincenzi; Anna Rita Cappello; Alessio Lodola; Simona Saponara; Stefania Butini; Gabriele Carullo; Sandra Gemma; Giuseppe Campiani
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err收藏
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication双靶向EphAs和KDR轴抑制VEGF诱导的血管生成和胶质瘤干细胞复制
errBiochemical Pharmacology
IF5.6
err2025-10-03
err0
errOAAI
errAlfonso Zappia; Francesca Romana Ferrari; Carmine Giorgio; Stefano Sala; Ilaria Zanotti; Simona Parrinello; Melanie P. Clements; Marco Rusnati; Michela Corsini; Andrea Blesio; Riccardo Castelli; Lorenzo Guidetti; Laura Scalvini; Alessio Lodola; Massimiliano Tognolini
err分享
err收藏
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor利用基于吲哚烷基的HDAC6抑制剂衍生的PROTAC工具逆转TGF-β1诱导的人肺成纤维细胞的纤维化表型
errEuropean Journal of Medicinal Chemistry Reports
IF4.1
err2025-05-21
err0
errOAAI
errIlaria Cursaro; Valerio Ciccone; Valeria Tudino; Chiara Papulino; Laura Scalvini; Sandra Donnini; Lucia Morbidelli; Luca Bini; Claudia Landi; Chiara Contri; Silvia Pasquini; Fabrizio Vincenzi; Katia Varani; Alessio Lodola; Marco Mor; Rosaria Benedetti; Lucia Altucci; Stefania Butini; Gabriele Carullo; Sandra Gemma; Giuseppe Campiani
err分享
err收藏
JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy SimulationsJAK3抑制剂: 通过多尺度自由能模拟研究的氨腈基团的共价和非共价相互作用
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-01-16
err0
PREAI
errScalvini, Laura; Pala, Daniele; Cuzzolin, Alberto; Galvani, Francesca; Lodola, Alessio; Rivara, Silvia; Mor, Marco; Rizzi, Andrea
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Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines靶向葡萄糖饥饿诱导的代谢适应性反应抑制奥希替尼耐药非小细胞肺癌 (NSCLC) 细胞系的细胞增殖并增加细胞死亡
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-10-01
err1
errOAAI
errEltayeb, Kamal; Alfieri, Roberta; Fumarola, Claudia; Bonelli, Mara; Galetti, Maricla; Cavazzoni, Andrea; Digiacomo, Graziana; Galvani, Francesca; Vacondio, Federica; Lodola, Alessio; Mor, Marco; Minari, Roberta; Tiseo, Marcello; La Monica, Silvia; Petronini, Pier Giorgio
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err收藏
Pharmacological characterization and improved PK of new small protein-protein-interaction inhibitors targeting the Eph-ephrin system
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errGiorgio, C.; Ferrari, F. R.; Zappia, A.; Sonvico, F.; Patterlini, V.; Castelli, R.; Lodola, A.; Tognolini, M.
err分享
err收藏
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line在U251胶质母细胞瘤细胞系上发现具有抗增殖活性的靶向EphA2受体的新1-(苯磺酰基)-1h-吲哚衍生物
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err2
errOAAI
errGuidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
err分享
err收藏
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models靶向葡萄糖神经酰胺合酶在奥希替尼耐药的NSCLC细胞模型中诱导抗增殖和促凋亡作用
errSCIENTIFIC REPORTS
IF3.9
err2024-03-18
err1
errOAAI
errLa Monica, Silvia; Vacondio, Federica; Eltayeb, Kamal; Lodola, Alessio; Volta, Francesco; Viglioli, Martina; Ferlenghi, Francesca; Galvani, Francesca; Galetti, Maricla; Bonelli, Mara; Fumarola, Claudia; Cavazzoni, Andrea; Flammini, Lisa; Verze, Michela; Minari, Roberta; Petronini, Pier Giorgio; Tiseo, Marcello; Mor, Marco; Alfieri, Roberta
err分享
err收藏
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-01-18
err2
errOAAI
errMedrano, Francisco J.; de la Hoz-Rodriguez, Sergio; Marti, Sergio; Arafet, Kemel; Schirmeister, Tanja; Hammerschmidt, Stefan J.; Mueller, Christin; Gonzalez-Martinez, Agueda; Santillana, Elena; Ziebuhr, John; Romero, Antonio; Zimmer, Collin; Weldert, Annabelle; Zimmermann, Robert; Lodola, Alessio; Swiderek, Katarzyna; Moliner, Vicent; Gonzalez, Florenci V.
err分享
err收藏
Drug discovery: In silico dry data can bypass biological wet data?
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2023-11-14
err1
errOAAI
errTognolini, Massimiliano; Lodola, Alessio; Giorgio, Carmine
err分享
err收藏
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-11-01
err2
errOAAI
errGuidetti, Lorenzo; Zappia, Alfonso; Scalvini, Laura; Ferrari, Francesca Romana; Giorgio, Carmine; Castelli, Riccardo; Galvani, Francesca; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Urbinati, Chiara; Rusnati, Marco; Tognolini, Massimiliano; Lodola, Alessio
err分享
err收藏
A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy EvidenceEph-ephrin拮抗前列腺癌的药理研究: UniPR1331疗效证据
errPHARMACEUTICALS
IF4.8
err2023-10-13
err1
errOAAI
errFestuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine
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Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations通过元动力学模拟解释毒蕈碱M3受体拮抗剂的解结合动力学
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-04-13
err3
errOAAI
errGalvani, Francesca; Pala, Daniele; Cuzzolin, Alberto; Scalvini, Laura; Lodola, Alessio; Mor, Marco; Rizzi, Andrea
err分享
err收藏
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2023-03-01
err4
PREAI
errFerrari, Francesca Romana; Giorgio, Carmine; Zappia, Alfonso; Ballabeni, Vigilio; Bertoni, Simona; Barocelli, Elisabetta; Scalvini, Laura; Galvani, Francesca; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
err分享
err收藏
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible AgentsEGFR C797S中Lys745磺酰化的机理模型揭示了抑制剂活性的化学决定因素，并区分了可逆和不可逆的药物
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-02-10
err10
errOAAI
errArafet, Kemel; Scalvini, Laura; Galvani, Francesca; Marti, Sergio; Moliner, Vicent; Mor, Marco; Lodola, Alessio
err分享
err收藏
Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-01-01
err10
PREAI
errPapa, Alessandro; Pasquini, Silvia; Galvani, Francesca; Cammarota, Mariarosaria; Contri, Chiara; Carullo, Gabriele; Gemma, Sandra; Ramunno, Anna; Lamponi, Stefania; Gorelli, Beatrice; Saponara, Simona; Varani, Katia; Mor, Marco; Campiani, Giuseppe; Boscia, Francesca; Vincenzi, Fabrizio; Lodola, Alessio; Butini, Stefania
err分享
err收藏
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency甘油单酯脂肪酶共价修饰的机理模型阐明了离去基团排出的作用，并区分了高效力和低效的抑制剂
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2022-05-17
err6
errOAAI
errGalvani, Francesca; Scalvini, Laura; Rivara, Silvia; Lodola, Alessio; Mor, Marco
err分享
err收藏
In silico drug discovery of melatonin receptor ligands with therapeutic potential具有治疗潜力的褪黑素受体配体的计算机药物发现
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2022-03-08
err7
PREAI
errElisi, Gian Marco; Scalvini, Laura; Lodola, Alessio; Bedini, Annalida; Spadoni, Gilberto; Rivara, Silvia
err分享
err收藏
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids靶向eph-ephrin系统的蛋白质-蛋白质相互作用抑制剂，重点是胆汁酸的氨基酸缀合物
errPHARMACEUTICALS
IF4.8
err2022-01-24
err7
errOAAI
errGuidetti, Lorenzo; Castelli, Riccardo; Scalvini, Laura; Ferlenghi, Francesca; Corrado, Miriam; Giorgio, Carmine; Tognolini, Massimiliano; Lodola, Alessio
err分享
err收藏

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