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Magdaléna Májeková

Slovak Academy of Sciences

H指数:18

被引数:1,400

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Design of fluorinated triazinoindoles as highly potent and markedly selective ALR2 inhibitors: synthesis, in silico and in vitro evaluation of promising lead compounds

氟代三氮唑吲哚类化合物的设计：作为高效且显著选择性的醛糖还原酶抑制剂的合成、计算机模拟和体外评价的潜在先导化合物

Bioorganic Chemistry

IF4.7

2026-08-040

PRE

Polyphenolic Compounds Activate SERCA1a and Attenuate Methylglyoxal- and Palmitate-Induced Impairment in Pancreatic INS-1E Beta Cells

IF5.2

2024-11-091

OAAI

Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-01-016

PRE

Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications

IF4.6

2021-05-1217

OAAI

Phenolic Compounds from Morus nigra Regulate Viability and Apoptosis of Pancreatic β-Cells Possibly via SERCA Activity

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-03-265

OAAI

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-12-1021

OAAI

Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors

IF4.6

2019-11-2012

OAAI

Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents

DRUG DEVELOPMENT RESEARCH

IF4.2

2019-08-307

OAAI

Ligand-based drug design of novel aldose reductase inhibitors

FUTURE MEDICINAL CHEMISTRY

IF3.4

2018-11-306

OAAI

Dysfunction of SERCA pumps as novel mechanism of methylglyoxal cytotoxicity

IF4

2018-09-018

PREAI

Electrochemical behavior of sarco/endoplasmic reticulum Ca-ATPase in response to carbonylation processes

JOURNAL OF ELECTROANALYTICAL CHEMISTRY

IF4.1

2018-03-015

PREAI

Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-12-0114

PREAI

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

FRONTIERS IN NEUROSCIENCE

IF3.2

2016-08-2263

OAAI

Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1′-diphenyl-2-picrylhydrazyl assay and in the cellular system of isolated erythrocytes exposed to tert-butyl hydroperoxide

IF7.4

2016-02-0511

OAAI

Indole- and Chromane-type heterocycles: Playing with molecules to defeat ageing

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2015-09-012

PREAI

Identification of Novel Aldose Reductase Inhibitors Based on Carboxymethylated Mercaptotriazinoindole Scaffold

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-03-0444

PREAI

Rutin stimulates sarcoplasmic reticulum Ca2+-ATPase activity (SERCA1) and protects SERCA1 from peroxynitrite mediated injury

MOLECULAR AND CELLULAR BIOCHEMISTRY

IF3.7

2014-12-307

PREAI

2-Chloro-1,4-naphthoquinone derivative of quercetin as an inhibitor of aldose reductase and anti-inflammatory agent

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2014-03-2535

OAAI

Novel quercetin derivatives in treatment of peroxynitrite-oxidized SERCA1

MOLECULAR AND CELLULAR BIOCHEMISTRY

IF3.7

2013-10-1918

PRE

2-Chloro-1,4-naphthoquinone derivative of quercetin as an efficient inhibitor of AKR1B1 and AKR1B10. Implications for diabetic complications, inflammatory disorders and cancer

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2013-09-011

PREAI