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A

Amr K. A. Bass

Al Azhar University
H指数:8
被引数:298

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Multitarget anti-inflammatory celecoxib-based hybrids: Design, synthesis, and mechanistic evaluation of COX-2/5-LOX/sEH modulation with liposomal formulation, ADMET profiling, and molecular dynamics studies

基于塞来昔布的多靶点抗炎杂合体：脂质体制剂、ADMET表征及分子动力学研究对COX-2/5-LOX/sEH调节的设计、合成与机制评价

Journal of Molecular Structure
IF4.7
2026-08-010
PRE
Soltan, Osama M.; Abdelrahman, Kamal S.; Ouf, Abdelsalam Mohamed Abdelsalam; Amin, Mohammed M.; Abdelbaset, Mahmoud S.; Hegazy, Mohamed E.; El-Rashedy, Ahmed A.; Hamdi, Abdelrahman; Elafify, Mohamed S.; Ueda, Motoki; Asayama, Shoichiro; Narumi, Atsushi; Konno, Hiroyuki; Bass, Amr K. A.
Design and development of 1,5-diarylpyrazole-based multitarget-directed ligands as dual COX-2/HDAC6 inhibitors for Alzheimer’s disease therapy: Molecular dynamics and experimental insights

基于1,5-二芳基吡唑的双靶点导向配体作为COX-2/HDAC6双重抑制剂的阿尔茨海默病疗法：分子动力学与实验见解

European Journal of Medicinal Chemistry
IF5.9
2026-03-020
PRE
Kamal S. Abdelrahman; Osama M. Soltan; Hend E. Abo Mansour; Amany E. Nofal; Eman A. Eissa; Heba Rady Salem; Marwa M. Mahfouz; Samar A. El-Adawy; Ghada S.A. Ewies; Abdelrahman Hamdi; Mostafa M. Elbadawi; Ahmed H.A. Abusabaa; Ahmed A. El-Rashedy; Hiroyuki Konno; Amr K.A. Bass

研究方向

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M
Mona S. El‐Zoghbi
H 指数:12论文数:32被引数:493
H
Hiroyuki Konno
H 指数:55论文数:655被引数:1.6万
G
Gamal El‐Din A. Abuo‐Rahma
H 指数:35论文数:135被引数:3,831
H
Hanan Al-Ghulikah
H 指数:16论文数:56被引数:766
A
Abdelrahman Hamdi
H 指数:14论文数:45被引数:494
M
Mohamed Badr
H 指数:14论文数:29被引数:547
M
Mamdouh F. A. Mohamed
H 指数:24论文数:73被引数:1,814
A
Ahmed A. El‐Rashedy
H 指数:18论文数:130被引数:1,261
N
Nada Osama
H 指数:7论文数:11被引数:251
O
Osama M. Soltan
H 指数:8论文数:15被引数:334