Arthur Eugen Kümmerle - Publications, H-index & Citations

Arthur Eugen Kümmerle

universidade federal rural do rio de janeiro (ufrrj)

22H指数

97论文数

2.6K被引数

收录论文 30

发表时间

Synthesis and Pharmacological Evaluation of Novel 1,5-Disubstituted-3-amino-1,2,4-triazoles Designed as Multitarget Directed Ligands for Alzheimer's Disease Targets 新型1,5-二取代-3-氨基-1,2,4-三唑类化合物的合成及其作为阿尔茨海默病靶点多靶点导向配体的药理学评价

ACS Omega

IF4.3

2026-02-01

OAAI

Franco, Daiana Portella; Caruso, Lucas; Grillo, Danniel Cosme Neves; Nadur, Nathalia Fonseca; de Azevedo, Luciana Luiz; Pereira, Thiago Moreira; da Silva, Manuelle Cunha; Lacerda, Renata Barbosa; Pinheiro, Pedro de Sena Murteira; Riger, Cristiano Jorge; Kummerle, Arthur Eugen

Imidazo[1,2-a]pyridines in Medicinal Chemistry: Recent Advances in Synthesis and Biological Activities

ACS OMEGA

IF4.3

2026-01-01

PREAI

Ferreira, Larissa A. P.; Caruso, Lucas; Nadur, Nathalia F.; Franco, Daiana P.; Sousa, Gleyton L. S.; Lacerda, Renata B.; Kummerle, Arthur E.

Illuminating zinc ions in solution: Selective fluorescence detection with a simple coumarin-thiosemicarbazone sensor 溶液中锌离子的荧光检测：使用简单香豆素-硫代氨基硼腙传感器的选择性荧光检测

Dyes and Pigments

IF4.2

2025-11-06

PREAI

Thiago Moreira Pereira; Henrique de Castro Silva Junior; Lilian Camargo da Luz; Márcio Soares Pereira; Fabio da Silva Miranda; Clarissa Oliveira da Silva; Fabiano Severo Rodembusch; Arthur Eugen Kümmerle

Design, Synthesis, and Biological Evaluation of Novel Multitarget 7-Alcoxyamino-3-(1,2,3-triazole)-coumarins as Potent Acetylcholinesterase Inhibitors 设计、合成及新型多靶点7-羟氨基-3-(1,2,3-三唑基)-香豆素的生物活性评价：作为强效乙酰胆碱酯酶抑制剂

Pharmaceuticals 2025, Vol. 18, Page 1398

IF4.8

2025-09-21

OAAI

Nathalia F. Nadur; Larissa de A. P. Ferreira; Daiana P. Franco; Luciana L. de Azevedo; Lucas Caruso; Thiago da S. Honório; Priscila de S. Furtado; Alice Simon; Lucio M. Cabral; Tobias Werner; Holger Stark; Arthur E. Kümmerle

Design and synthesis of novel fluorescent amino-chalcones as turn-on probes for prion protein fibril detection 新型荧光氨基查尔酮的设计与合成及其作为检测朊病毒蛋白纤维的“开启”探针

Journal of Molecular Structure

IF4.7

2025-07-28

PREAI

Lucas Machado Ascari; Lucas Caruso; Gabriel S․ Ribeiro; Ingrid Del Castilo; Rafaela M. Lazaroni; Raissa Alves da Conceição; João Victor Teixeira Gomes; Fabio da Silva Miranda; Bianca Aloise Maneira Corrêa Santos; Maria Leticia C. Barbosa; Arthur E. Kümmerle; Yraima Cordeiro

Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-01-01

PREAI

Sousa, Gleyton Leonel Silva; Nadur, Nathalia Fonseca; Ferreira, Larissa de Almeida Peixoto; Honorio, Thiago da Silva; Simon, Alice; Cabral, Lucio Mendes; Santos, Maria Luiza Mora; Andrade, Bruna; de Lima, Emanuelle V.; Clarke, Julia R.; Castro, Rosane Nora; Moura, Ricardo Olimpio de; Kummerle, Arthur Eugen

Structure-based design of new N-benzyl-piperidine derivatives as multitarget-directed AChE/BuChE inhibitors for Alzheimer's disease

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2023-10-05

OAAI

da Conceicao, Raissa Alves; von Ranke, Natalia; Azevedo, Luciana; Franco, Daiana; Nadur, Nathalia Fonseca; Kummerle, Arthur Eugen; Barbosa, Maria Leticia de C.; Souza, Alessandra M. T.

Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine-Thiosemicarbazone Derivatives

PHARMACEUTICALS

IF4.8

2022-09-02

OAAI

Sousa, Gleyton; de Almeida, Maria C. F.; Locio, Lucas L.; dos Santos, Vanda L.; Bezerra, Daniel P.; Silva, Valdenizia R.; de Almeida, Sinara M., V; Simon, Alice; Honorio, Thiago da S.; Cabral, Lucio M.; Castro, Rosane N.; de Moura, Ricardo O.; Kummerle, Arthur E.

Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation

RSC MEDICINAL CHEMISTRY

IF3.6

2022-01-01

OAAI

Cristancho Ortiz, Cindy Juliet; Silva, Matheus de Freitas; Pruccoli, Letizia; Nadur, Nathalia Fonseca; de Azevedo, Luciana Luiza; Kummerle, Arthur Eugen; Guedes, Isabella Alvim; Dardenne, Laurent Emmanuel; Leomil Coelho, Luiz Felipe; Guimaraes, Marcos J.; da Silva, Fernanda M. R.; Castro, Newton; Gontijo, Vanessa Silva; Rojas, Viviana C. T.; de Oliveira, Merelym Ketterym; Vilela, Fabiana Cardoso; Giusti-Paiva, Alexandre; Barbosa, Gisele; Lima, Lidia Moreira; Pinheiro, Gabriela Beserra; Veras, Leticia Germino; Mortari, Marcia Renata; Tarozzi, Andrea; Viegas Jr, Claudio

The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure 设计磷酸二酯酶抑制剂治疗心力衰竭的漫长而曲折的道路

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-02-01

PREAI

Nadur, Nathalia Fonseca; de Azevedo, Luciana Luiz; Caruso, Lucas; Graebin, Cedric Stephan; Lacerda, Renata Barbosa; Kummerle, Arthur Eugen

Cytotoxicity evaluation and DNA interaction of RuII-bipy complexes containing coumarin-based ligands

DALTON TRANSACTIONS

IF3.3

2021-01-01

PREAI

de Almeida, Patricia S. V. B.; de Arruda, Henrique Jefferson; Sousa, Gleyton Leonel S.; Ribeiro, Felipe Vitorio; de Azevedo-Franca, Jose Aleixo; Ferreira, Larissa A.; Guedes, Guilherme P.; Silva, Heveline; Kummerle, Arthur E.; Neves, Amanda P.

Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases

NEUROCHEMICAL RESEARCH

IF3.8

2020-10-20

PREAI

Ortiz, Cindy Juliet Cristancho; Damasio, Caio Miranda; Pruccoli, Letizia; Nadur, Nathalia Fonseca; de Azevedo, Luciana Luiza; Guedes, Isabella Alvim; Dardenne, Laurent Emmanuel; Kummerle, Arthur Eugen; Tarozzi, Andrea; Viegas, Claudio

Design, Synthesis and Biological Evaluation of Novel TriazoleN-acylhydrazone Hybrids for Alzheimer's Disease

MOLECULES

IF4.6

2020-07-10

OAAI

Silva, Matheus de Freitas; Lima, Ellen Tardelli; Pruccoli, Letizia; Castro, Newton G.; Guimaraes, Marcos Jorge R.; da Silva, Fernanda M. R.; Nadur, Nathalia Fonseca; de Azevedo, Luciana Luiz; Kummerle, Arthur Eugen; Guedes, Isabella Alvim; Dardenne, Laurent Emmanuel; Gontijo, Vanessa Silva; Tarozzi, Andrea; Viegas, Claudio

Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2019-02-06

OAAI

de Souza, Gabriela Alves; da Silva, Soraia John; Del Cistia, Catarina de Nigris; Pitasse-Santos, Paulo; Pires, Lucas de Oliveira; Passos, Yulli Moraes; Cordeiro, Yraima; Cardoso, Cristiane Martins; Castro, Rosane Nora; Sant'Anna, Carlos Mauricio R.; Kummerle, Arthur Eugen

Novel CoIII complexes containing fluorescent coumarin-N-acylhydrazone hybrid ligands: Synthesis, crystal structures, solution studies and DFT calculations

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

IF4.6

2017-12-01

PREAI

Areas, Esther S.; Bronsato, Bruna Juliana da S.; Pereira, Thiago M.; Guedes, Guilherme P.; Miranda, Fabio da S.; Kummerle, Arthur E.; da Cruz, Antonio G. B.; Neves, Amanda P.

Structure-Based Discovery of Thiosemicarbazone Metalloproteinase Inhibitors for Hemorrhage Treatment in Snakebites

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2017-10-04

OAAI

Ferreira, Francis B.; Pereira, Thiago M.; Souza, Dayane L. N.; Lopes, Daiana S.; Freitas, Vitor; Avila, Veridiana M. R.; Kummerle, Arthur E.; Sant'Anna, Carlos Mauricio R.

In vivo effect of LASSBio-785, a lipid-lowering and anti-inflammatory agent, on cardiac Ca2+-ATPases from hypercholesterolemic rats

INTERNATIONAL JOURNAL OF CARDIOLOGY

IF3.2

2015-12-01

PREAI

Marques, Emiliana B.; Motta, Nadia A. V.; Kummerle, Arthur E.; Fraga, Carlos A. M.; Barreiro, Eliezer J.; Brito, Fernanda C. F.; Scaramello, Christianne B. V.

N-acylhydrazone improves exercise intolerance in rats submitted to myocardial infarction by the recovery of calcium homeostasis in skeletal muscle

LIFE SCIENCES

IF5.1

2014-01-01

PREAI

da Silva, Jaqueline Soares; Pereira, Sharlene Lopes; Maia, Rodolfo do Couto; Landgraf, Sharon Schilling; Caruso-Neves, Celso; Kuemmerle, Arthur Eugen; Manssour Fraga, Carlos Alberto; Barreiro, Eliezer Jesus; Sudo, Roberto Takashi; Zapata-Sudo, Gisele

Characterization of Amide Bond Conformers for a Novel Heterocyclic Template of N-acylhydrazone Derivatives

MOLECULES

IF4.6

2013-09-25

OAAI

Lopes, Alexandra Basilio; Miguez, Eduardo; Kuemmerle, Arthur Eugen; Rumjanek, Victor Marcos; Manssour Fraga, Carlos Alberto; Barreiro, Eliezer J.

A novel Ca2+ channel antagonist reverses cardiac hypertrophy and pulmonary arteriolar remodeling in experimental pulmonary hypertension

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2013-02-01

PREAI

Pereira, Sharlene Lopes; Kummerle, Arthur Eugen; Manssour Fraga, Carlos Alberto; Barreiro, Eliezer Jesus; Rocha, Nazareth de Novaes; Ferraz, Emanuelle Baptista; Matheus do Nascimento, Jose Hamilton; Sudo, Roberto Takashi; Zapata-Sudo, Gisele

研究方向