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Fisayo A. Olotu

university of kwazulu natal

H指数:20

被引数:1,115

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Allosteric modulation of Plasmodium falciparum Isoleucyl tRNA synthetase by South African natural compounds

恶性疟原虫异亮氨酰-tRNA合成酶的别构调节：南非天然化合物的作用

IF2.6

2025-05-140

OA

Repurposing DrugBank compounds as potential Plasmodium falciparum class 1a aminoacyl tRNA synthetase multi-stage pan-inhibitors with a specific focus on mitomycin

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2024-08-010

OAAI

Betulinic acid purified from Alstonia boonei inhibits folate biosynthesis in malarial Plasmodium, enhances mitochondrial pore opening and F1F0 ATPase in mice

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2021-09-019

PREAI

Integrative immunoinformatics paradigm for predicting potential B-cell and T-cell epitopes as viable candidates for subunit vaccine design against COVID-19 virulence

预测潜在b细胞和T细胞表位的整合免疫信息学范式可作为针对新型冠状病毒肺炎毒力的亚单位疫苗设计的可行候选者

BIOMEDICAL JOURNAL

IF4.4

2021-08-0110

OAAI

Immunoinformatics prediction of potential B-cell and T-cell epitopes as effective vaccine candidates for eliciting immunogenic responses against Epstein-Barr virus

BIOMEDICAL JOURNAL

IF4.4

2021-06-0116

OAAI

Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-03-0120

OAAI

Design, synthesis, and evaluation of dual-site-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-02-0117

OAAI

Formamidine-based thiuram disulfides: Synthesis, structural characterization, biological studies, and preliminary cheminformatics evaluation

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2020-11-0115

PREAI

Probing the Highly Disparate Dual Inhibitory Mechanisms of Novel Quinazoline Derivatives against Mycobacterium tuberculosis Protein Kinases A and B

IF4.6

2020-09-162

OAAI

In vitro, in silico studies of newly isolated tetrahydro-4-(7-hydroxy-10-methoxy-6, 14-dimethyl-15-m-tolylpentadec-13-enyl) pyran-2-one and isobutyryl acetate compounds from Alstonia boonei stem bark

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2020-09-013

PREAI

Impact of HEC72702 chirality on the selective inhibition of hepatitis B virus capsid dimer: A dynamics-structure-energetics perspective

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2020-08-261

PREAI

The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2020-07-2114

PREAI

Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-12-0132

PREAI

'Piperazining' the catalytic gatekeepers: unraveling the pan-inhibition of SRC kinases; LYN, FYN and BLK by masitinib

FUTURE MEDICINAL CHEMISTRY

IF3.4

2019-09-133

PREAI

Deciphering the canonical blockade of activated Hageman factor (FXIIa) by benzamidine in the coagulation cascade: A thorough dynamical perspective

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-07-212

PREAI

Halting ionic shuttle to disrupt the synthetic machinery-Structural and molecular insights into the inhibitory roles of Bedaquiline towards Mycobacterium tuberculosis ATP synthase in the treatment of tuberculosis

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2019-05-2411

PREAI

Covalent simulations of covalent/irreversible enzyme inhibition in drug discovery: a reliable technical protocol

FUTURE MEDICINAL CHEMISTRY

IF3.4

2018-10-0114

PREAI

An update on the discovery and development of selective heat shock protein inhibitors as anti-cancer therapy

选择性热休克蛋白抑制剂作为抗癌疗法的发现和发展的最新进展

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2018-09-1215

PREAI

Dynamic perspectives into the mechanisms of mutation-induced p53-DNA binding loss and inactivation using active perturbation theory: Structural and molecular insights toward the design of potent reactivators in cancer therapy

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2018-08-3019

OAAI

Probing Gallate-Mediated Selectivity and High-Affinity Binding of Epigallocatechin Gallate: a Way-Forward in the Design of Selective Inhibitors for Anti-apoptotic Bcl-2 Proteins

探索没食子儿茶素没食子酸酯介导的选择性和高亲和力结合: 抗凋亡Bcl-2蛋白选择性抑制剂设计的前进方向

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

IF3.3

2018-08-2925

PREAI