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G

Glenn S. Cowley

j&j innovative medicine
H指数:46
被引数:1.9万

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Identification of a novel dependency between PRMT5 and APC-LOF in preclinical models of FAP disease

在FAP疾病预临床模型中鉴定PRMT5与APC-LOF之间的一种新型依赖关系

Communications Biology
IF5.1
2026-10-030
OA
Dana Gaffney; Fabian Hulpia; Jan Willem Thuring; Eileen Vesely; Edward Retzbach; Zienab Etwebi; Zhengyu Jiang; Albi Francis; Bethany Mattson; Alexandra Liddane; Kathleen W. Clancy; Froylan Omar Fernandez Candelaria; Yi Fan; Constance Smith-Monroy; Glenn S. Cowley; Victoria Wong; Prashanth Gokare; Sylvia F. Boj; Carla S. Verissimo; Rene Overmeer; Mariana Silva; Gerben ten Hag; Johan Nicolaï; Mark Hixon; Gerald Chu; Andrea DiSandro; Kurtis E. Bachman; David Pocalyko
SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
CELL REPORTS
IF6.9
2024-08-011
OAAI
Chang, Yu-Hsuan; Yamamoto, Keita; Fujino, Takeshi; Wang, Teh-Wei; Sugimoto, Emi; Zhang, Wenyu; Yabushita, Tomohiro; Suzaki, Ken; Pietsch, E. Christine; Weir, Barbara A.; Crescenzo, Ramona; Cowley, Glenn S.; Attar, Ricardo; Philippar, Ulrike; Wunderlich, Mark; Mizukawa, Benjamin; Zheng, Yi; Enomoto, Yutaka; Imai, Yoichi; Kitamura, Toshio; Goyama, Susumu
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin
COMMUNICATIONS BIOLOGY
IF5.1
2024-04-080
OAAI
Mittal, Karuna; Cooper, Garrett W.; Lee, Benjamin P.; Su, Yongdong; Skinner, Katie T.; Shim, Jenny; Jonus, Hunter C.; Kim, Won Jun; Doshi, Mihir; Almanza, Diego; Kynnap, Bryan D.; Christie, Amanda L.; Yang, Xiaoping; Cowley, Glenn S.; Leeper, Brittaney A.; Morton, Christopher L.; Dwivedi, Bhakti; Lawrence, Taylor; Rupji, Manali; Keskula, Paula; Meyer, Stephanie; Clinton, Catherine M.; Bhasin, Manoj; Crompton, Brian D.; Tseng, Yuen-Yi; Bohm, Jesse S.; Ligon, Keith L.; Root, David E.; Murphy, Andrew J.; Weinstock, David M.; Gokhale, Prafulla C.; Spangle, Jennifer M.; Rivera, Miguel N.; Mullen, Elizabeth A.; Stegmaier, Kimberly; Goldsmith, Kelly C.; Hahn, William C.; Hong, Andrew L.
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion
BLOOD ADVANCES
IF7.1
2022-03-157
OAAI
Stalmann, Ursula S. A.; Ticconi, Fabio; Snoeren, Inge A. M.; Li, Ronghui; Gleitz, Helene F. E.; Cowley, Glenn S.; McConkey, Marie E.; Wong, Aaron B.; Schmitz, Stephani; Fuchs, Stijn N. R.; Sood, Shubhankar; Leimkuehler, Nils B.; Martinez-Hoyer, Sergio; Banjanin, Bella; Root, David; Bruemmendorf, Tim H.; Pearce, Juliette E.; Schuppert, Andreas; Bindels, Eric M. J.; Essers, Marieke A.; Heckl, Dirk; Stiehl, Thomas; Costa, Ivan G.; Ebert, Benjamin L.; Schneider, Rebekka K.
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor
NATURE COMMUNICATIONS
IF15.7
2020-06-0114
OAAI
Eller, Carla; Heydmann, Laura; Colpitts, Che C.; El Saghire, Houssein; Piccioni, Federica; Juhling, Frank; Majzoub, Karim; Pons, Caroline; Bach, Charlotte; Lucifora, Julie; Lupberger, Joachim; Nassal, Michael; Cowley, Glenn S.; Fujiwara, Naoto; Hsieh, Sen-Yung; Hoshida, Yujin; Felli, Emanuele; Pessaux, Patrick; Sureau, Camille; Schuster, Catherine; Root, David E.; Verrier, Eloi R.; Baumert, Thomas F.
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma
NATURE COMMUNICATIONS
IF15.7
2019-06-0338
OAAI
Bandopadhayay, Pratiti; Piccioni, Federica; O'Rourke, Ryan; Ho, Patricia; Gonzalez, Elizabeth M.; Buchan, Graham; Qian, Kenin; Gionet, Gabrielle; Girard, Emily; Coxon, Margo; Rees, Matthew G.; Brenan, Lisa; Dubois, Frank; Shapira, Ofer; Greenwald, Noah F.; Pages, Melanie; Iniguez, Amanda Balboni; Paolella, Brenton R.; Meng, Alice; Sinai, Claire; Roti, Giovanni; Dharia, Neekesh V.; Creech, Amanda; Tanenbaum, Benjamin; Khadka, Prasidda; Tracy, Adam; Tiv, Hong L.; Hong, Andrew L.; Coy, Shannon; Rashid, Rumana; Lin, Jia-Ren; Cowley, Glenn S.; Lam, Fred C.; Goodale, Amy; Lee, Yenarae; Schoolcraft, Kathleen; Vazquez, Francisca; Hahn, William C.; Tsherniak, Aviad; Bradner, James E.; Yaffe, Michael B.; Milde, Till; Pfister, Stefan M.; Qi, Jun; Schenone, Monica; Carr, Steven A.; Ligon, Keith L.; Kieran, Mark W.; Santagata, Sandro; Olson, James M.; Gokhale, Prafulla C.; Jaffe, Jacob D.; Root, David E.; Stegmaier, Kimberly; Johannessen, Cory M.; Beroukhim, Rameen
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
CANCER DISCOVERY
IF33.3
2019-02-08129
OA
Oser, Matthew G.; Fonseca, Raquel; Chakraborty, Abhishek A.; Brough, Rachel; Spektor, Alexander; Jennings, Rebecca B.; Flaifel, Abdallah; Novak, Jesse S.; Gulati, Aditi; Buss, Elizabeth; Younger, Scott T.; McBrayer, Samuel K.; Cowley, Glenn S.; Bonal, Dennis M.; Nguyen, Quang-De; Brulle-Soumare, Laura; Taylor, Paula; Cairo, Stefano; Ryan, Colm J.; Pease, Elizabeth J.; Maratea, Kim; Travers, Jon; Root, David E.; Signoretti, Sabina; Pellman, David; Ashton, Susan; Lord, Christopher J.; Barry, Simon T.; Kaelin, William G., Jr.
Small-molecule targeting of brachyury transcription factor addiction in chordoma
NATURE MEDICINE
IF50
2019-01-21125
OAAI
Sharifnia, Tanaz; Wawer, Mathias J.; Chen, Ting; Huang, Qing-Yuan; Weir, Barbara A.; Sizemore, Ann; Lawlor, Matthew A.; Goodale, Amy; Cowley, Glenn S.; Vazquez, Francisca; Ott, Christopher J.; Francis, Joshua M.; Sassi, Slim; Cogswell, Patricia; Sheppard, Hadley E.; Zhang, Tinghu; Gray, Nathanael S.; Clarke, Paul A.; Blagg, Julian; Workman, Paul; Sommer, Josh; Hornicek, Francis; Root, David E.; Hahn, William C.; Bradner, James E.; Wong, Kwok K.; Clemons, Paul A.; Lin, Charles Y.; Kotz, Joanne D.; Schreiber, Stuart L.
REPLY TO HAFFNER ET AL.: DNA hypomethylation renders tumors more immunogenic
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2018-09-045
OAAI
Stone, Meredith L.; Chiappinelli, Katherine B.; Li, Huili; Murphy, Lauren M.; Travers, Meghan E.; Topper, Michael J.; Mathios, Dimitrios; Lim, Michael; Shih, Le-Ming; Wang, Tian-Li; Hung, Chien-Fu; Bhargava, Vipul; Wiehagen, Karla R.; Cowley, Glenn S.; Bachman, Kurtis E.; Strick, Reiner; Strissel, Pamela L.; Baylin, Stephen B.; Zahnow, Cynthia A.
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2017-12-04113
OA
Chen, Liying; Alexe, Gabriela; Dharia, Neekesh V.; Ross, Linda; Iniguez, Amanda Balboni; Conway, Amy Saur; Wang, Emily Jue; Veschi, Veronica; Lam, Norris; Qi, Jun; Gustafson, W. Clay; Nasholm, Nicole; Vazquez, Francisca; Weir, Barbara A.; Cowley, Glenn S.; Ali, Levi D.; Pantel, Sasha; Jiang, Guozhi; Harrington, William F.; Lee, Yenarae; Goodale, Amy; Lubonja, Rakela; Krill-Burger, John M.; Meyers, Robin M.; Tsherniak, Aviad; Root, David E.; Bradner, James E.; Golub, Todd R.; Roberts, Charles W. M.; Hahn, William C.; Weiss, William A.; Thiele, Carol J.; Stegmaier, Kimberly
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2017-12-04229
OAAI
Stone, Meredith L.; Chiappinelli, Katherine B.; Li, Huili; Murphy, Lauren M.; Travers, Meghan E.; Topper, Michael J.; Mathios, Dimitrios; Lim, Michael; Shih, Ie-Ming; Wang, Tian-Li; Hung, Chien-Fu; Bhargava, Vipul; Wiehagen, Karla R.; Cowley, Glenn S.; Bachman, Kurtis E.; Strick, Reiner; Strissel, Pamela L.; Baylin, Stephen B.; Zahnow, Cynthia A.
A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines
CELL SYSTEMS
IF7.7
2017-11-0116
OAAI
Gonen, Mehmet; Weir, Barbara A.; Cowley, Glenn S.; Vazquez, Francisca; Guan, Yuanfang; Jaiswal, Alok; Karasuyama, Masayuki; Uzunangelov, Vladislav; Wang, Tao; Tsherniak, Aviad; Howell, Sara; Marbach, Daniel; Hoff, Bruce; Norman, Thea C.; Airola, Antti; Bivol, Adrian; Bunte, Kerstin; Carlin, Daniel; Chopra, Sahil; Deran, Alden; Ellrott, Kyle; Gopalacharyulu, Peddinti; Graim, Kiley; Kaski, Samuel; Khan, Suleiman A.; Newton, Yulia; Ng, Sam; Pahikkala, Tapio; Paull, Evan; Sokolov, Artem; Tang, Hao; Tang, Jing; Wennerberg, Krister; Xie, Yang; Zhan, Xiaowei; Zhu, Fan; Aittokallio, Tero; Mamitsuka, Hiroshi; Stuart, Joshua M.; Boehm, Jesse S.; Root, David E.; Xiao, Guanghua; Stolovitzky, Gustavo; Hahn, William C.; Margolin, Adam A.
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
NATURE GENETICS
IF31.8
2017-10-301.3K
OAAI
Meyers, Robin M.; Bryan, Jordan G.; McFarland, James M.; Weir, Barbara A.; Sizemore, Ann E.; Xu, Han; Dharia, Neekesh V.; Montgomery, Phillip G.; Cowley, Glenn S.; Pantel, Sasha; Goodale, Amy; Lee, Yenarae; Ali, Levi D.; Jiang, Guozhi; Lubonja, Rakela; Harrington, William F.; Strickland, Matthew; Wu, Ting; Hawes, Derek C.; Zhivich, Victor A.; Wyatt, Meghan R.; Kalani, Zohra; Chang, Jaime J.; Okamoto, Michael; Stegmaier, Kimberly; Golub, Todd R.; Boehm, Jesse S.; Vazquez, Francisca; Root, David E.; Hahn, William C.; Tsherniak, Aviad
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer
CANCER RESEARCH
IF16.6
2017-08-3129
OAAI
Hsu, Jessie Hao-Ru; Hubbell-Engler, Benjamin; Adelmant, Guillaume; Huang, Jialiang; Joyce, Cailin E.; Vazquez, Francisca; Weir, Barbara A.; Montgomery, Philip; Tsherniak, Aviad; Giacomelli, Andrew O.; Perry, Jennifer A.; Trowbridge, Jennifer; Fujiwara, Yuko; Cowley, Glenn S.; Xie, Huafeng; Kim, Woojin; Novina, Carl D.; Hahn, William C.; Marto, Jarrod A.; Orkin, Stuart H.

研究方向

暂未获取到该数据
D
David E. Root
H 指数:106论文数:816被引数:7.0万
W
William C. Hahn
H 指数:147论文数:1,091被引数:10.1万
B
Barbara A. Weir
H 指数:52论文数:288被引数:4.4万
F
Francisca Vázquez
H 指数:76论文数:520被引数:3.3万
A
Aviad Tsherniak
H 指数:55论文数:224被引数:2.5万
L
Levi A. Garraway
H 指数:147论文数:1,018被引数:14.8万
J
Jesse S. Boehm
H 指数:59论文数:332被引数:4.2万
K
Kimberly Stegmaier
H 指数:64论文数:757被引数:2.2万
T
Todd R. Golub
H 指数:176论文数:757被引数:26.7万
B
Benjamin L. Ebert
H 指数:122论文数:775被引数:15.3万