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Kimberly Stegmaier

Dana-Farber Cancer Institute and Boston Children's Hospital

64H指数
757论文数
2.2W被引数
收录论文 137
发表时间
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SNHG family lncRNAs promote Ewing sarcoma cell fitness through intronic snoRNA-guided rRNA modificationsSNHG家族长链非编码RNA通过内含子snoRNA引导的rRNA修饰促进尤文肉瘤细胞活力
errNAR Cancer
IF3.2
err2026-08-26
err0
errOAAI
errMarcela Briones-Martin-del-Campo; Alex G Lee; Truc Dinh; Virginie Marchand; Yuri Motorin; Marta Román; Qiuli Bi; Stanley G Leung; Max A Horlbeck; Leanne C Sayles; Bo Kyung Alex Seong; Luke Gilbert; Kimberly Stegmaier; E Alejandro Sweet-Cordero
err分享
err收藏
Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia剪接相关网络PAK1-CLK1/4-SRRM1是人类和小鼠急性髓系白血病克服化疗耐药的易感靶点
errScience Translational Medicine
IF14.6
err2026-07-08
err0
PREAI
errCamille Vaganay; Frank Ling; Lois M. Kelly; Juliette Charles; Paul-Arthur Meslin; Hélène Pasquer; Rathana Kim; Marie Passet; Matthieu Duchmann; Léa Pelissier-Menjaud; Séverine Lecourt; Angela H. Su; Emmanuelle Latour; Christopher F. Bassil; Gabriela Alexe; Gael Fortin; Duong Ho Nhat; Cécile Culeux; Carine Legrand; Sofiane Fodil; Tony Huynh; Khansa Saadallah; Azucena Ramos; Bérangère Lombard; Damarys Loew; Christopher D. Delaney; Catherine Lonchamp; Morgane Fontaine; Kim Pacchiardi; Anja Kocijancic; Lisa Aziez; Nina Fenouille; Marie Sebert; Lionel Adès; Emmanuel Raffoux; Michael T. Hemann; Emmanuelle Clappier; Lina Benajiba; Kimberly Stegmaier; Kris C. Wood; Raphaël Itzykson; Antoine Forget; Camille Lobry; Alexandre Puissant
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err收藏
Copper depletion boosts CNS leukemia therapy by inhibiting nucleotide synthesis through impairment of mitochondrial complex IV activity铜耗竭通过线粒体复合物IV活性受损抑制核苷酸合成来促进中枢神经系统白血病治疗
errNature Cancer
IF28.5
err2026-05-25
err0
PREAI
errAlan Y. L. Wong; Jacob W. Myers; Gyan Prakash; Alice Ma; Jeannette R. Brook; Boryana Petrova; Baran Bulut; Ralph White; Catherine Merz; Maeve de Souza; Adam G. Maynard; Peng Wang; Amy Yu; Nancy K. Pohl; Michal Weitman; Lewis B. Silverman; Kimberly Stegmaier; L. Stirling Churchman; Peter D. Cole; Donita C. Brady; Naama Kanarek
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Identifying targeted therapies for CBFA2T3::GLIS2 acute myeloid leukemia识别CBFA2T3::GLIS2急性髓系白血病的靶向疗法
errLeukemia
IF13.4
err2026-01-08
err0
errOAAI
errFanny Gonzales; Constanze Schneider; Gabriela Alexe; Shan Lin; Delan Khalid; Montserrat Alvarez; Allen Basanthakumar; Jana M. Ellegast; Lucy Merickel; Silvi Salhotra; Audrey Taillon; Mariateresa Giaimo; Mark Wunderlich; Marc Ansari; Jennifer A. Perry; Barbara Degar; Yana Pikman; Kimberly Stegmaier
err分享
err收藏
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemiasMECOM对CEBPA的抑制阻止了分化，从而驱动了侵袭性白血病。
errBlood
IF23.1
err2025-09-26
err0
errOAAI
errTravis J. Fleming; Mateusz Antoszewski; Sander Lambo; Michael C. Gundry; Riccardo Piussi; Lara Wahlster; Sanjana Shah; Fiona E. Reed; Kevin D. Dong; Joao A. Paulo; Steven P. Gygi; Claudia Mimoso; Seth R. Goldman; Karen Adelman; Jennifer A. Perry; Yana Pikman; Kimberly Stegmaier; Maria N. Barrachina; Kellie R. Machlus; Volker Hovestadt; Andrea Arruda; Mark D. Minden; Richard A. Voit; Vijay G. Sankaran
err分享
err收藏
Combining MCL-1 inhibition and CD37-directed chimeric antigen receptor T cells as an effective strategy to target T-cell lymphoma联合MCL-1抑制剂和CD37靶向嵌合抗原受体T细胞作为靶向T细胞淋巴瘤的有效策略
errLeukemia
IF13.4
err2025-07-30
err0
errOAAI
errTayla B. Heavican-Foral; Felix Korell; Irene Scarfò; Caroline R. M. Wiggers; Allen Thayakumar B; Zachary Eisenbies; Foster Powers; Justin Hegel; Jianlin Liu; Steffen Kulp; Harrison Silva; Gongwei Wu; Anthony Letai; Kimberly Stegmaier; Jens G. Lohr; David M. Weinstock; Marcela V. Maus; Birgit Knoechel
err分享
err收藏
JAK2 inhibition mediates clonal selection of RAS pathway mutations in myeloproliferative neoplasmsJAK2 抑制介导了骨髓增殖性肿瘤中 RAS 通路突变的克隆选择。
errNature Communications
IF15.7
err2025-07-08
err0
errOAAI
errNabih Maslah; Nina Kaci; Blandine Roux; Gabriela Alexe; Raphael Marie; Hélène Pasquer; Emmanuelle Verger; Rafael Daltro De Oliveira; Cécile Culeux; Bochra Mlayah; Nicolas Gauthier; Fanny Gonzales; Lin-Pierre Zhao; Saravanan Ganesan; Panhong Gou; Frank Ling; Juliette Soret-Dulphy; Nathalie Parquet; William Vainchenker; Emmanuel Raffoux; Rose Ann Padua; Stéphane Giraudier; Caroline Marty; Isabelle Plo; Camille Lobry; Kimberly Stegmaier; Alexandre Puissant; Jean-Jacques Kiladjian; Bruno Cassinat; Lina Benajiba
err分享
err收藏
Prospects for understanding and exploiting the consequences of hyperactivation lethality理解与利用超活化致死效应后果的前景
errTrends in Cancer
IF17.5
err2025-05-19
err0
errOAAI
errKatharin Shaw; René Bernards; Kimberly Stegmaier; Harold Varmus; William R. Sellers
err分享
err收藏
Inflammatory signaling pathways play a role in SYK inhibitor resistant AML炎症信号通路在SYK抑制剂耐药AML中的作用
errSCIENTIFIC REPORTS
IF3.9
err2025-04-05
err0
errOAAI
errTausch, Sarah; Villinger, Christina; Alexe, Gabriela; Urban, Daniel J.; Shen, Min; Jahn, Dominique; Vischedyk, Jonas; Scheich, Sebastian; Serve, Hubert; Hall, Matthew D.; Stegmaier, Kimberly; Oellerich, Thomas; Cremer, Anjali
err分享
err收藏
ADARI Is a Vulnerability in TP53-Mutant Acute Myeloid LeukemiaADARI 是 TP53 突变急性髓系白血病中的易损性。
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errRodriguez, Yara; Alexe, Gabriela; Taillon, Audrey; Schneider, Constanze; Stegmaier, Kimberly
err分享
err收藏
Posttranslational Changes in Histone Modification Driven By USP48 Loss Increase Sensitivity to Hypomethylating Agents in Acute Myeloid LeukemiaUSP48缺失驱动的组蛋白修饰翻译后变化增加了急性髓系白血病对低甲基化药物的敏感性
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errSchneider, Constanze; Alexe, Gabriela; Meyer, Ashleigh; Merickel, Lucy A.; Basanthakumar, Allen T.; Taillon, Audrey; Salhotra, Silvi; Rodriguez, Yara; Haeupl, Bjoern; Root, David E.; Oellerich, Thomas; Stegmaier, Kimberly
err分享
err收藏
Therapeutic targeting of the SAGA KAT module impairs MYCN-amplified neuroblastoma growth through reduction of the MYCN oncogenic gene expression program
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errMabe, Nathaniel W.; Malone, Clare F.; Forman, Alexandra B.; Alexe, Gabriela; Engel, Kathleen L.; Chen, Ying-Jiun C.; Soeung, Melinda; Salhotra, Silvi; Basanthakumar, Allen; Liu, Bin; Dent, Sharon Y. R.; Stegmaier, Kimberly
err分享
err收藏
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
errDEVELOPMENTAL CELL
IF8.7
err2024-08-01
err1
errOAAI
errDo, Brian T.; Hsu, Peggy P.; Vermeulen, Sidney Y.; Wang, Zhishan; Hirz, Taghreed; Abbott, Keene L.; Aziz, Najihah; Replogle, Joseph M.; Bjelosevic, Stefan; Paolino, Jonathan; Nelson, Samantha A.; Block, Samuel; Darnell, Alicia M.; Ferreira, Raphael; Zhang, Hanyu; Milosevic, Jelena; Schmidt, Daniel R.; Chidley, Christopher; Harris, Isaac S.; Weissman, Jonathan S.; Pikman, Yana; Stegmaier, Kimberly; Cheloufi, Sihem; Su, Xiaofeng A.; Sykes, David B.; Vander Heiden, Matthew G.
err分享
err收藏
Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia
errCANCER RESEARCH
IF16.6
err2024-07-18
err1
PREAI
errSchneider, Constanze; Spaink, Hermes; Alexe, Gabriela; Dharia, Neekesh V.; Meyer, Ashleigh; Merickel, Lucy A.; Khalid, Delan; Scheich, Sebastian; Haeupl, Bjoern; Staudt, Louis M.; Oellerich, Thomas; Stegmaier, Kimberly
err分享
err收藏
Pharmacological targeting of the cancer epigenome
errNATURE CANCER
IF28.5
err2024-06-27
err8
PREAI
errMabe, Nathaniel W.; Perry, Jennifer A.; Malone, Clare F.; Stegmaier, Kimberly
err分享
err收藏
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
errSCIENCE ADVANCES
IF12.5
err2024-05-31
err3
errOAAI
errMalone, Clare F.; Mabe, Nathaniel W.; Forman, Alexandra B.; Alexe, Gabriela; Engel, Kathleen L.; Chen, Ying-Jiun C.; Soeung, Melinda; Salhotra, Silvi; Basanthakumar, Allen; Liu, Bin; Dent, Sharon Y. R.; Stegmaier, Kimberly
err分享
err收藏
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-04-08
err0
errOAAI
errMittal, Karuna; Cooper, Garrett W.; Lee, Benjamin P.; Su, Yongdong; Skinner, Katie T.; Shim, Jenny; Jonus, Hunter C.; Kim, Won Jun; Doshi, Mihir; Almanza, Diego; Kynnap, Bryan D.; Christie, Amanda L.; Yang, Xiaoping; Cowley, Glenn S.; Leeper, Brittaney A.; Morton, Christopher L.; Dwivedi, Bhakti; Lawrence, Taylor; Rupji, Manali; Keskula, Paula; Meyer, Stephanie; Clinton, Catherine M.; Bhasin, Manoj; Crompton, Brian D.; Tseng, Yuen-Yi; Bohm, Jesse S.; Ligon, Keith L.; Root, David E.; Murphy, Andrew J.; Weinstock, David M.; Gokhale, Prafulla C.; Spangle, Jennifer M.; Rivera, Miguel N.; Mullen, Elizabeth A.; Stegmaier, Kimberly; Goldsmith, Kelly C.; Hahn, William C.; Hong, Andrew L.
err分享
err收藏
EWS-FLI1-driven upregulation of UGT3A2 unlocks drug sensitivity pathway in Ewing sarcoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errOlaoye, Olasunkanmi; Harrington, Colleen; Ross, Kenneth; Seong, Bo Kyung A.; de Waal, Luk; Qi, Jun; Roth, Jennifer; Stegmaier, Kimberly
err分享
err收藏
ATM and PARP combined inhibition demonstrate synergistic antitumor efficacy in osteosarcoma models
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errKocinsky, Sona N.; Morsby, Janeala J.; Wright, William C.; Wierdl, Monika; Wechsler, Caroline S.; Alexe, Gabriela; Geeleher, Paul; Stegmaier, Kimberly; Guenther, Lillian M.
err分享
err收藏
Rewiring EWS/FLI1 with transcriptional chemical inducers of proximity (TCIPs)
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBond, Michael J.; Golden, Ryan P.; Sarott, Roman C.; DiGiovanni, Giulia; Karim, Basel A.; Howard, Briana; Ross, Kenneth; Gray, Nathanael S.; Stegmaier, Kimberly
err分享
err收藏

研究方向

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合作学者
合作期刊
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Róbert Langer
H 指数: 262 · 论文数: 2.0K
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Gad Getz
H 指数: 248 · 论文数: 1.8K
M
Matthew Meyerson
H 指数: 223 · 论文数: 1.9K
L
Lewis C. Cantley
H 指数: 214 · 论文数: 1.4K
T
Todd R. Golub
H 指数: 176 · 论文数: 749
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