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J

Joshua M. Dempster

broad institute of mit and harvard
H指数:27
被引数:4,442

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A dependency map enhanced with next-generation 3D cancer models

一张融合了新一代3D癌症模型的药物靶点互作图

Nature
IF48.5
2026-08-050
OA
James V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez
BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

BAF复杂扰动作为H3K27M小儿神经胶质瘤的新治疗机会

NEURO-ONCOLOGY
IF13.4
2023-06-120
OAAI
Panditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh; Hoffman, Samantha; Kugener, Guillaume; Shaw, McKenzie; Hack, Olivia; Dempster, Joshua; Lareau, Caleb; Quezada, Michael; Stanton, Ann-Catherine; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John; Root, David; Anastas, Jamie; Jones, Kristen; Conway, Amy; Stopka, Sylwia; Regan, Michael; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Mathewson, Nathan; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Nguyen, Quang-De; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias
NATURE CANCER
IF28.5
2023-05-2615
PRE
Simoes, Ricardo de Matos; Shirasaki, Ryosuke; Downey-Kopyscinski, Sondra L.; Matthews, Geoffrey M.; Barwick, Benjamin G.; Gupta, Vikas A.; Dupere-Richer, Daphne; Yamano, Shizuka; Hu, Yiguo; Sheffer, Michal; Dhimolea, Eugen; Dashevsky, Olga; Gandolfi, Sara; Ishiguro, Kazuya; Meyers, Robin M.; Bryan, Jordan G.; Dharia, Neekesh V.; Hengeveld, Paul J.; Bruggenthies, Johanna B.; Tang, Huihui; Aguirre, Andrew J.; Sievers, Quinlan L.; Ebert, Benjamin L.; Glassner, Brian J.; Ott, Christopher J.; Bradner, James E.; Kwiatkowski, Nicholas P.; Auclair, Daniel; Levy, Joan; Keats, Jonathan J.; Groen, Richard W. J.; Gray, Nathanael S.; Culhane, Aedin C.; McFarland, James M.; Dempster, Joshua M.; Licht, Jonathan D.; Boise, Lawrence H.; Hahn, William C.; Vazquez, Francisca; Tsherniak, Aviad; Mitsiades, Constantine S.
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas
CANCER DISCOVERY
IF33.3
2022-12-2815
OAAI
Cervia, Lisa D.; Shibue, Tsukasa; Borah, Ashir A.; Gaeta, Benjamin; He, Linh; Leung, Lisa; Li, Naomi; Moyer, Sydney M.; Shim, Brian H.; Dumont, Nancy; Gonzalez, Alfredo; Bick, Nolan R.; Kazachkova, Mariya; Dempster, Joshua M.; Krill-Burger, John Michael; Piccioni, Federica; Udeshi, Namrata D.; Olive, Meagan E.; Carr, Steven A.; Root, David E.; McFarland, James M.; Vazquez, Francisca; Hahn, William C.
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
CANCER DISCOVERY
IF33.3
2022-11-1127
OAAI
Panditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria C.; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh, V; Li, Deyao; Hoffman, Samantha E.; Kugener, Guillaume; Shaw, McKenzie L.; Mire, Hafsa M.; Hack, Olivia A.; Dempster, Joshua M.; Lareau, Caleb; Dai, Lingling; Sigua, Logan H.; Quezada, Michael A.; Stanton, Ann-Catherine J.; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John G.; Root, David E.; Anastas, Jamie N.; Jones, Kristen L.; Conway, Amy Saur; Stopka, Sylwia; Regan, Michael S.; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Jerome, William P.; Mathewson, Nathan D.; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Quang-De Nguyen; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.

研究方向

暂未获取到该数据
F
Francisca Vázquez
H 指数:76论文数:520被引数:3.3万
D
David E. Root
H 指数:106论文数:815被引数:6.9万
W
William C. Hahn
H 指数:147论文数:1,091被引数:10.1万
J
James M. McFarland
H 指数:36论文数:232被引数:1.3万
A
Aviad Tsherniak
H 指数:55论文数:224被引数:2.5万
T
Todd R. Golub
H 指数:176论文数:757被引数:26.6万
J
Jesse S. Boehm
H 指数:59论文数:332被引数:4.2万
I
Isabella Boyle
H 指数:7论文数:19被引数:854
J
John G. Doench
H 指数:80论文数:737被引数:4.3万
J
John M. Krill-Burger
H 指数:25论文数:91被引数:6,107