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Targeting TUBG1 in RB1-negative tumors Lindstrom, Lisa; Zhou, Jingkai; Villoutreix, Bruno O.; Malycheva, Darina; Otrocka, Magdalena; Gustavsson, Anna-Lena; Lundback, Thomas; Bliman, David; Shameem, Muhammad Anwar; Straw, Megan; Riesbeck, Kristian; Olsson, Roger; Alvarado-Kristensson, Maria Share Save
Closing the Design-Make-Test-Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability Valencia, Zulma Santisteban; Kingston, Jennifer; Miljkovic, Filip; Rowbottom, Hannah; Mann, Nadia; Davies, Sophie; Ekblad, Martin; Di Castro, Silvio; Kwapien, Karolina; Malmerberg, Erik; Friis, Stig D.; Lundback, Thomas; Leek, Tomas; Wernevik, Johan Share Save
Identification of epidermal growth factor receptor-tyrosine kinase inhibitor targeting the VP1 pocket of human rhinovirus Miah, Masum; Davis, Andrew M.; Hannoun, Charles; Said, Joanna S.; Fitzek, Martina; Preston, Marian; Smith, Dave; Uwamariya, Colores; Karmander, Ambjorn; Lundback, Thomas; Bergstrom, Tomas; Trybala, Edward Share Save
All-photonic kinase inhibitors: light-controlled release-and-report inhibition Fleming, Cassandra L.; Benitez-Martin, Carlos; Bernson, Elin; Xu, Yongjin; Kristenson, Linnea; Inghardt, Tord; Lundback, Thomas; Thoren, Fredrik B.; Grotli, Morten; Andreasson, Joakim Share Save
Rapid PROTAC Discovery Platform: Nanomole-Scale Array Synthesis and Direct Screening of Reaction Mixtures Plesniak, Mateusz P.; Taylor, Emilia K.; Eisele, Frederik; Kourra, Christopher M. B. K.; Michaelides, Iacovos N.; Oram, Alice; Wernevik, Johan; Valencia, Zulma Santisteban; Rowbottom, Hannah; Mann, Nadia; Fredlund, Linda; Pivnytska, Valentyna; Noven, Anna; Pirmoradian, Mohammad; Lundback, Thomas; Storer, R. Ian; Pettersson, Mariell; De Donatis, Gian M.; Rehnstrom, Marie Share Save
Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1 Wallner, Olov; Cazares-Korner, Armando; Scaletti, Emma Rose; Masuyer, Geoffrey; Bekkhus, Tove; Visnes, Torkild; Mamonov, Kirill; Ortis, Florian; Lundback, Thomas; Volkova, Maria; Koolmeister, Tobias; Wiita, Elisee; Loseva, Olga; Pandey, Monica; Homan, Evert; Benitez-Buelga, Carlos; Davies, Jonathan; Scobie, Martin; Berglund, Ulrika Warpman; Kalderen, Christina; Stenmark, Pal; Helleday, Thomas; Michel, Maurice Share Save
Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils; Lof, Liza; Arngarden, Linda; Blokzijl, Andries; Svensson, Richard; Hammond, Maria; Lonn, Peter; Haybaeck, Johannes; Kamali-Moghaddam, Masood; Jensen, Annika Jenmalm; Danielson, U. Helena; Artursson, Per; Lundback, Thomas; Landegren, Ulf Share Save
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Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound Giovannucci, Tatiana A.; Salomons, Florian A.; Haraldsson, Martin; Elfman, Lotta H. M.; Wickstroem, Malin; Young, Patrick; Lundbaeck, Thomas; Eirich, Juergen; Altun, Mikael; Jafari, Rozbeh; Gustavsson, Anna-Lena; Johnsen, John Inge; Dantuma, Nico P. Share Save
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Development of a chemical probe against NUDT15 Zhang, Si Min; Desroses, Matthieu; Hagenkort, Anna; Valerie, Nicholas C. K.; Rehling, Daniel; Carter, Megan; Wallner, Olov; Koolmeister, Tobias; Throup, Adam; Jemth, Ann-Sofie; Almlof, Ingrid; Loseva, Olga; Lundback, Thomas; Axelsson, Hanna; Regmi, Shruti; Sarno, Antonio; Kraemer, Andreas; Pudelko, Linda; Brautigam, Lars; Rasti, Azita; Gottmann, Mona; Wiita, Elisee; Kutzner, Juliane; Schaller, Torsten; Kalderen, Christina; Cazares-Korner, Armando; Page, Brent D. G.; Krimpenfort, Rosa; Eshtad, Saeed; Altun, Mikael; Rudd, Sean G.; Knapp, Stefan; Scobie, Martin; Homan, Evert J.; Berglund, Ulrika Warpman; Stenmark, Pal; Helleday, Thomas Share Save
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase Wilkes, M. C.; Siva, K.; Chen, J.; Varetti, G.; Youn, M. Y.; Chae, H.; Ek, F.; Olsson, R.; Lundback, T.; Dever, D. P.; Nishimura, T.; Narla, A.; Glader, B.; Nakauchi, H.; Porteus, M. H.; Repellin, C. E.; Gazda, H. T.; Lin, S.; Serrano, M.; Flygare, J.; Sakamoto, K. M. Share Save
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Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy Rudd, Sean G.; Tsesmetzis, Nikolaos; Sanjiv, Kumar; Paulin, Cynthia B. J.; Sandhow, Lakshmi; Kutzner, Juliane; Myrberg, Ida Hed; Bunten, Sarah S.; Axelsson, Hanna; Zhang, Si Min; Rasti, Azita; Makela, Petri; Coggins, Si'Ana A.; Tao, Sijia; Suman, Sharda; Branca, Rui M.; Mermelekas, Georgios; Wiita, Elisee; Lee, Sun; Walfridsson, Julian; Schinazi, Raymond F.; Kim, Baek; Lehtio, Janne; Rassidakis, Georgios Z.; Tamm, Katja Pokrovskaja; Warpman-Berglund, Ulrika; Heyman, Mats; Grander, Dan; Lehmann, Soren; Lundback, Thomas; Qian, Hong; Henter, Jan-Inge; Schaller, Torsten; Helleday, Thomas; Herold, Nikolas Share Save
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells (vol 9, 250, 2018) Page, Brent D. G.; Valerie, Nicholas C. K.; Wright, Roni H. G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlof, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundback, Thomas; Scobie, Martin; Stromberg, Kia; Stenmark, Pal; Beato, Miguel; Helleday, Thomas Share Save
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A drug screening assay on cancer cells chronically adapted to acidosis Pellegrini, Paola; Serviss, Jason T.; Lundback, Thomas; Bancaro, Nicolo; Mazurkiewicz, Magdalena; Kolosenko, Iryna; Yu, Di; Haraldsson, Martin; D'Arcy, Padraig; Linder, Stig; De Milito, Angelo Share Save
Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors Stefaniak, Jakub; Lewis, Andrew M.; Conole, Daniel; Galan, Sebastien R. G.; Bataille, Carole J. R.; Wynne, Graham M.; Castaldi, M. Paola; Lundback, Thomas; Russell, Angela J.; Huber, Kilian V. M. Share Save
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