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收藏Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer
Park, Yoon Sun; Kim, Joseph; Ryu, Yea Seong; Moon, Jai-Hee; Shin, Yu Jin; Kim, Jeong Hee; Hong, Seung-Woo; Jung, Soo-A; Lee, Seul; Kim, Seung-Mi; Lee, Dae Hee; Kim, Do Yeon; Yun, Hyeseon; You, Ji-Eun; Yoon, Dong Il; Kim, Chul Hee; Koh, Dong-In; Jin, Dong-Hoon
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收藏DGG-300273, a novel WNT/β-catenin inhibitor, induces apoptotic cell death by activating ROS-BIM signaling in a Wnt-dependent manner in colon cancer cellsDGG-300273是一种新型的WNT/β-catenin抑制剂,可通过激活ros-bim信号以Wnt依赖性方式诱导结肠癌细胞凋亡。
Kim, Do Yeon; Ryu, Yea Seong; Lee, Eun-Sil; Koh, Dong-In; Moon, Jai-Hee; Jung, Soo-A; Kim, Mi Jin; Yun, Hyeseon; You, Ji-Eun; Jeong, Hong-Rae; Yoon, Dong-Il; Kim, Chul Hee; Hong, Seung-Woo; Gong, Young-Dae; Jin, Dong-Hoon
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