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Xiaoyan Chu

Department of Pharmacokinetics
H指数:47
被引数:1.0万

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荣誉奖项

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Characterization of organic anion transporting polypeptide (OATP)1B1 and OATP1B3 humanized rat as a translational model to study the pharmacokinetics of OATP1B substrate drugs

人有机阴离子转运多肽(OATP)1B1和OATP1B3人源化大鼠模型的表征：作为研究OATP1B底物药物药代动力学的转化模型

Drug Metabolism and Disposition
IF4
2025-06-020
PRE
Yang Li; Jocelyn Yabut; Zuo Zhang; Scott Fauty; Robert Houle; Hannah Miller; Nanyan Rena Zhang; Myung K. Shin; Thomas W. Rosahl; Heather H. Zhou; Bhagwat Prasad; Jashvant D. Unadkat; Xiaoyan Chu
Predicting OCT2/MATEs-Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

预测OCT2/MATEs介导的药物相互作用：来自扩展清除率概念、内源性生物标志物和体外抑制研究的见解（国际转运体联盟观点）

Clinical Pharmacology & Therapeutics
IF5.5
2025-05-270
OAAI
Satoshi Asano; Aleksandra Galetin; Yoshiko Tomita; Kathleen M. Giacomini; Xiaoyan Chu; Xinning Yang; Toshimichi Nakamura; Hiroyuki Kusuhara; Yuichi Sugiyama
Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers
CLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
2024-11-051
OAAI
Koishikawa, Tomoki; Fujiwara, Kaku; Taskar, Kunal; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Chu, Xiaoyan; Hirabayashi, Hideki; Mao, Jialin; Rockich, Kevin; Takashima, Tadayuki; Yamaura, Yoshiyuki; Lai, Yurong; Tomoda, Yukana; Kito, Tomoko; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
Membrane transporters in drug development and as determinants of precision medicine

药物开发中的膜转运蛋白和精准医学的决定因素

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2024-01-2438
PRE
Galetin, Aleksandra; Brouwer, Kim L. R.; Tweedie, Donald; Yoshida, Kenta; Sjostedt, Noora; Aleksunes, Lauren; Chu, Xiaoyan; Evers, Raymond; Hafey, Michael J.; Lai, Yurong; Matsson, Par; Riselli, Andrew; Shen, Hong; Sparreboom, Alex; Varma, Manthena V. S.; Yang, Jia; Yang, Xinning; Yee, Sook Wah; Zamek-Gliszczynski, Maciej J.; Zhang, Lei; Giacomini, Kathleen M.
Physiologically-based pharmacokinetic model-based translation of OATP1B-mediated drug-drug interactions from coproporphyrin I to probe drugs
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
2022-05-0222
OA
Mochizuki, Tatsuki; Aoki, Yasunori; Yoshikado, Takashi; Yoshida, Kenta; Lai, Yurong; Hirabayashi, Hideki; Yamaura, Yoshiyuki; Rockich, Kevin; Taskar, Kunal; Takashima, Tadayuki; Chu, Xiaoyan; Zamek-Gliszczynski, Maciej J.; Mao, Jialin; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions
CLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
2022-04-1124
OAAI
Mochizuki, Tatsuki; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Mao, Jialin; Taskar, Kunal; Hirabayashi, Hideki; Chu, Xiaoyan; Lai, Yurong; Takashima, Tadayuki; Rockich, Kevin; Yamaura, Yoshiyuki; Fujiwara, Kaku; Mizuno, Tadahaya; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment
CLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
2020-10-2636
PREAI
Tatosian, Daniel A.; Yee, Ka Lai; Zhang, Zufei; Mostoller, Kate; Paul, Erina; Sutradhar, Santosh; Larson, Patrick; Chhibber, Aparna; Wen, Jianzhong; Wang, Ya-Juan; Lassman, Michael; Latham, Andrew H.; Pang, Jianmei; Crumley, Tami; Gillespie, Anne; Marricco, Nadia Cardillo; Marenco, Ted; Murphy, Matthew; Lasseter, Kenneth C.; Marbury, Thomas C.; Tweedie, Donald; Chu, Xiaoyan; Evers, Raymond; Stoch, S. Aubrey
Mechanism of deoxynivalenol-induced neurotoxicity in weaned piglets is linked to lipid peroxidation, dampened neurotransmitter levels, and interference with calcium signaling

脱氧雪腐镰刀菌烯醇诱导的断奶仔猪神经毒性的机制与脂质过氧化，抑制神经递质水平和干扰钙信号有关

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
IF6.1
2020-05-0125
PREAI
Wang, Xichun; Chen, Xiaofang; Cao, Li; Zhu, Lei; Zhang, Yafei; Chu, Xiaoyan; Zhu, Dianfeng; Rahman, Sajid Ur; Peng, Chenglu; Feng, Shibin; Li, Yu; Wu, Jinjie

研究方向

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R
Raymond Evers
H 指数:56论文数:178被引数:1.4万
Y
Yuichi Sugiyama
H 指数:112论文数:1,119被引数:5.0万
M
Maciej J. Zamek‐Gliszczynski
H 指数:36论文数:81被引数:7,237
Y
Yurong Lai
H 指数:57论文数:234被引数:8,778
A
Aleksandra Galetin
H 指数:58论文数:249被引数:9,423
J
Jocelyn Yabut
H 指数:17论文数:36被引数:1,762
K
Kenta Yoshida
H 指数:31论文数:112被引数:3,593
K
Kathleen M. Giacomini
H 指数:80论文数:441被引数:2.5万
H
Hiroyuki Kusuhara
H 指数:84论文数:457被引数:1.9万
K
Kunal S. Taskar
H 指数:19论文数:56被引数:2,122