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Yurong Lai

gilead sciences inc

57H指数
234论文数
8.8K被引数
收录论文 80
发表时间
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Mechanism-guided Untargeted-to-targeted Lipidomics Identifies Phosphatidylcholine 38:4 in Rat Bile as an Abcb4/Mdr2 Inhibition Marker机制引导的靶向外-靶向脂质组学鉴定出大鼠胆汁中的磷脂酰胆碱38:4为Abcb4/Mdr2抑制标志物
errDrug Metabolism and Disposition
IF4
err2026-02-24
err0
PREAI
errRenmeng Liu; Zachary Rabow; Tingyuan Yang; Xin Yan; Yiding Hu; Chenling Xiong; Yurong Lai
err分享
err收藏
Drug-Drug Interaction Assessments of Clinical Transporter Inhibition: Learnings from the Transporter Working Group from the International Consortium for Innovation and Quality in Pharmaceutical Development药物-药物相互作用评估的临床转运蛋白抑制作用：国际制药开发创新与质量联盟转运蛋白工作组的学习总结
errDrug Metabolism and Disposition
IF4
err2026-02-24
err0
PREAI
errRucha S. Sane; Pallabi Mitra; Yurong Lai; Cindy Yanfei Li; Hong Shen; Kimio Tohyama; Chester Costales; Laurent Salphati; Kelly M. Mahar; Daniel A.J. Bow; James M. Vergis; Jochen Brumm; Kunal Taskar; Hugues Chanteux; Zhizhou Fang; Xiaomin Liang; Seong Hee Park; Imad Hanna; Nilay Thakkar; Xiaoyan Chu
err分享
err收藏
Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2)BCRP/ABCG2（乳腺癌耐药蛋白）潜在生物标志物的鉴定与临床评估
errClinical Pharmacology & Therapeutics
IF5.5
err2025-04-01
err0
errOAAI
errAndrew M. Riselli; Sook Wah Yee; Jia Yang; Claire M. Brett; Kelsey Trumbach; Xujia Zhou; Renmeng Liu; Xiaomin Liang; Yurong Lai; Runlan Huo; Yongjun Xue
err分享
err收藏
Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-11-05
err1
errOAAI
errKoishikawa, Tomoki; Fujiwara, Kaku; Taskar, Kunal; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Chu, Xiaoyan; Hirabayashi, Hideki; Mao, Jialin; Rockich, Kevin; Takashima, Tadayuki; Yamaura, Yoshiyuki; Lai, Yurong; Tomoda, Yukana; Kito, Tomoko; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
err分享
err收藏
Membrane transporters in drug development and as determinants of precision medicine药物开发中的膜转运蛋白和精准医学的决定因素
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2024-01-24
err38
PREAI
errGaletin, Aleksandra; Brouwer, Kim L. R.; Tweedie, Donald; Yoshida, Kenta; Sjostedt, Noora; Aleksunes, Lauren; Chu, Xiaoyan; Evers, Raymond; Hafey, Michael J.; Lai, Yurong; Matsson, Par; Riselli, Andrew; Shen, Hong; Sparreboom, Alex; Varma, Manthena V. S.; Yang, Jia; Yang, Xinning; Yee, Sook Wah; Zamek-Gliszczynski, Maciej J.; Zhang, Lei; Giacomini, Kathleen M.
err分享
err收藏
Building a Predictive PBPK Model for Human OATP Substrates: a Strategic Framework for Early Evaluation of Clinical Pharmacokinetic Variations Using Pitavastatin as an Example
errAAPS JOURNAL
IF3.7
err2024-01-05
err1
PREAI
errLiang, Xiaomin; Koleske, Megan L.; Yang, Jesse; Lai, Yurong
err分享
err收藏
Toward improved predictions of pharmacokinetics of transported drugs in hepatic impairment: Insights from the extended clearance model
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2023-10-20
err1
errOAAI
errStorelli, Flavia; Ladumor, Mayur K.; Liang, Xiaomin; Lai, Yurong; Chothe, Paresh P.; Enogieru, Osatohanmwen J.; Evers, Raymond; Unadkat, Jashvant D.
err分享
err收藏
CBP-1018, a bi-ligand-drug conjugate treated in patients with advanced solid tumors: A phase I, multi-center, openlabel, dose-escalation and dose expansion study
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err1
errOAAI
errLi, K.; Wu, J.; Ye, S.; Liu, Y.; Huang, H.; Fan, F.; Lai, Y.; Zhuang, S.; Zhou, L.; Huang, R.; Teng, Y.; Chai, X.; Zhang, J.; Shi, Y.; Huang, H.
err分享
err收藏
Development of Triple-negative breast cancer (TNBC) syngeneic models and TROP2-directed antibody-drug conjugate (ADC) surrogate to model therapeutic combinations
errCANCER RESEARCH
IF16.6
err2023-03-01
err0
PREAI
errChou, Chih-Chien; Kardos, Jordan; Yang, Becky; Orf, Jessica; Dave, Rutwij; Lai, Yurong; Lee, Chingwei V.; Papalia, Giuseppe A.; Boyd, Kelli; Diehl, Lauri; Scholler, Nathalie
err分享
err收藏
Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2022-12-20
err7
errOAAI
errLadumor, Mayur K.; Storelli, Flavia; Liang, Xiaomin; Lai, Yurong; Enogieru, Osatohanmwen J.; Chothe, Paresh P.; Evers, Raymond; Unadkat, Jashvant D.
err分享
err收藏
NONCLINICAL SAFETY EVALUATION OF SACITUZUMAB GOVITECAN, A TROP-2-DIRECTED ANTIBODY DRUG CONJUGATE (ADC), FOR NON-MUSCLE INVASIVE BLADDER CANCER
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2022-11-07
err0
errOAAI
errMcMahon, Carrie; Diehl, Lauri; Tatalick, Laurie; Boggs, Jennifer; Mohanan, Sunish; Mah, In Kyoung; Kardos, Jordan; Chou, Chih-Chien; Niu, Congrong; Dave, Rutwij; Scholler, Nathalie; Lai, Yurong
err分享
err收藏
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humansADME科学的下一个前沿: 预测人类基于转运蛋白的药物处置，组织浓度和药物-药物相互作用
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2022-10-01
err24
errOAAI
errStorelli, Flavia; Yin, Mengyue; Kumar, Aditya R.; Ladumor, Mayur K.; Evers, Raymond; Chothe, Paresh P.; Enogieru, Osatohanmwen J.; Liang, Xiaomin; Lai, Yurong; Unadkat, Jashvant D.
err分享
err收藏
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2022-06-22
err22
errOAAI
errTaskar, Kunal S.; Yang, Xinning; Neuhoff, Sibylle; Patel, Mitesh; Yoshida, Kenta; Paine, Mary F.; Brouwer, Kim L. R.; Chu, Xiaoyan; Sugiyama, Yuichi; Cook, Jack; Polli, Joseph W.; Hanna, Imad; Lai, Yurong; Zamek-Gliszczynski, Maciej
err分享
err收藏
Transporters and Toxicity: Insights from the International Transporter Consortium Workshop 4
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2022-06-10
err9
PREAI
errHafey, Michael J.; Aleksunes, Lauren M.; Bridges, Christy C.; Brouwer, Kenneth R.; Chien, Huan-Chieh; Leslie, Elaine M.; Hu, Shuiying; Li, Yang; Shen, Jinshan; Sparreboom, Alex; Sprowl, Jason; Tweedie, Donald; Lai, Yurong
err分享
err收藏
Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development
errACTA PHARMACEUTICA SINICA B
IF14.6
err2022-06-01
err44
errOAAI
errLai, Yurong; Chu, Xiaoyan; Di, Li; Gao, Wei; Guo, Yingying; Liu, Xingrong; Lu, Chuang; Mao, Jialin; Shen, Hong; Tang, Huaping; Xia, Cindy Q.; Zhang, Lei; Ding, Xinxin
err分享
err收藏
Quantitative Expression of Drug, Phospholipid and Nucleoside Transporters in the Lung Tissues across Species
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errNiu, Congrong; Ma, Bin; Liu, Renmeng; Lai, Yurong
err分享
err收藏
Intestinal P-glycoprotein (P-gp) Contribution to Talinolol Pharmacokinetics in Human
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errWan, Christine; Ishida, Kazuya; Lai, Yurong
err分享
err收藏
Physiologically-based pharmacokinetic model-based translation of OATP1B-mediated drug-drug interactions from coproporphyrin I to probe drugs
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2022-05-02
err22
errOAAI
errMochizuki, Tatsuki; Aoki, Yasunori; Yoshikado, Takashi; Yoshida, Kenta; Lai, Yurong; Hirabayashi, Hideki; Yamaura, Yoshiyuki; Rockich, Kevin; Taskar, Kunal; Takashima, Tadayuki; Chu, Xiaoyan; Zamek-Gliszczynski, Maciej J.; Mao, Jialin; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
err分享
err收藏
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2022-04-11
err24
errOAAI
errMochizuki, Tatsuki; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Mao, Jialin; Taskar, Kunal; Hirabayashi, Hideki; Chu, Xiaoyan; Lai, Yurong; Takashima, Tadayuki; Rockich, Kevin; Yamaura, Yoshiyuki; Fujiwara, Kaku; Mizuno, Tadahaya; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki
err分享
err收藏
Kidney transporters drug discovery, development, and safety肾脏转运蛋白药物的发现、开发和安全性
errCURRENT OPINION IN TOXICOLOGY
IF3.6
err2022-03-01
err1
PREAI
errRadi, Zaher A.; Lai, Yurong
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
Y
Yuichi Sugiyama
H 指数: 112 · 论文数: 1.1K
张建 封面图
张建 (Jian Zhang)
H 指数: 99 · 论文数: 1.6K
A
Alex Sparreboom
H 指数: 98 · 论文数: 842
D
Dietrich Keppler
H 指数: 94 · 论文数: 338
P
Per Artursson
H 指数: 94 · 论文数: 375
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