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V

Vic E. Myer

nchromabio
H指数:32
被引数:2.0万

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荣誉奖项

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Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B

开发一种研究性表观遗传沉默疗法以转录失活慢性乙型肝炎病毒DNA

Nature Biomedical Engineering
IF26.6
2026-09-210
OAAI
Yesseinia Anglero-Rodriguez; Qiang Xiong; Martino Alfredo Cappelluti; Sarah B. Voytek; Glen Acosta; Rayman Choo-Wing; Lenka Hoffman; Arogya Khadka; Jhon A. Medina; Caroline Mugambwa; Chloe Pantano; Sivan Harel; Amber DiPiazza; Sameer Abraham; Erica M. Hildebrand; Ricardo N. Ramirez; Ava Zhai; Xiaoyun Guo; Sahar Abubucker; Chih-Wei Ko; Cristiana Giancarlo; Bradley Niesner; Matteo Conti; Lorena Donnici; Pietro Spinelli; Taesun Eom; Mary S. Morrison; Ari E. Friedland; Raffaele De Francesco; Angelo Lombardo; Vic E. Myer; Aron B. Jaffe; Melissa Bonner; Jennifer L. Marlowe
A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels

一种靶向人PCSK9的强效表观遗传编辑器，用于持久降低低密度脂蛋白胆固醇水平

NATURE MEDICINE
IF50
2025-02-103
OA
Tremblay, Frederic; Xiong, Qiang; Shah, Shrijal S.; Ko, Chih-Wei; Kelly, Kenneth; Morrison, Mary S.; Giancarlo, Cristiana; Ramirez, Ricardo N.; Hildebrand, Erica M.; Voytek, Sarah B.; El Sebae, Gabriel K.; Wright, Shane H.; Lofgren, Liam; Clarkson, Scott; Waters, Christine; Linder, Samantha J.; Liu, Songlei; Eom, Taesun; Parikh, Shefal; Weber, Yuki; Martinez, Salette; Malyala, Padma; Abubucker, Sahar; Friedland, Ari E.; Maeder, Morgan L.; Lombardo, Angelo; Myer, Vic E.; Jaffe, Aron B.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines (vol 12, 3908, 2021)
NATURE COMMUNICATIONS
IF15.7
2021-07-193
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

AsCas12a超核酸酶促进治疗细胞药物的快速生成

NATURE COMMUNICATIONS
IF15.7
2021-06-2377
OAAI
Zhang, Liyang; Zuris, John A.; Viswanathan, Ramya; Edelstein, Jasmine N.; Turk, Rolf; Thommandru, Bernice; Rube, H. Tomas; Glenn, Steve E.; Collingwood, Michael A.; Bode, Nicole M.; Beaudoin, Sarah F.; Lele, Swarali; Scott, Sean N.; Wasko, Kevin M.; Sexton, Steven; Borges, Christopher M.; Schubert, Mollie S.; Kurgan, Gavin L.; McNeill, Matthew S.; Fernandez, Cecilia A.; Myer, Vic E.; Morgan, Richard A.; Behlke, Mark A.; Vakulskas, Christopher A.
Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10
NATURE MEDICINE
IF50
2019-01-21512
PREAI
Maeder, Morgan L.; Stefanidakis, Michael; Wilson, Christopher J.; Baral, Reshica; Barrera, Luis Alberto; Bounoutas, George S.; Bumcrot, David; Chao, Hoson; Ciulla, Dawn M.; DaSilva, Jennifer A.; Dass, Abhishek; Dhanapal, Vidya; Fennell, Tim J.; Friedland, Ari E.; Giannoukos, Georgia; Gloskowski, Sebastian W.; Glucksmann, Alexandra; Gotta, Gregory M.; Jayaram, Hariharan; Haskett, Scott J.; Hopkins, Bei; Horng, Joy E.; Joshi, Shivangi; Marco, Eugenio; Mepani, Rina; Reyon, Deepak; Ta, Terence; Tabbaa, Diana G.; Samuelsson, Steven J.; Shen, Shen; Skor, Maxwell N.; Stetkiewicz, Pam; Wang, Tongyao; Yudkoff, Clifford; Myer, Vic E.; Albright, Charles F.; Jiang, Haiyan
Unexpected mutations after CRISPR-Cas9 editing in vivo
NATURE METHODS
IF32.1
2018-03-3022
PREAI
Wilson, Christopher J.; Fennell, Tim; Bothmer, Anne; Maeder, Morgan L.; Reyon, Deepak; Cotta-Ramusino, Cecilia; Fernandez, Cecilia A.; Marco, Eugenio; Barrera, Luis A.; Jayaram, Hariharan; Albright, Charles F.; Cox, Gerald F.; Church, George M.; Myer, Vic E.
SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice (vol 11, pg 511, 2015)
NATURE CHEMICAL BIOLOGY
IF13.7
2016-03-182
OAAI
Palacino, James; Swalley, Susanne E.; Song, Cheng; Cheung, Atwood K.; Shu, Lei; Zhang, Xiaolu; Van Hoosear, Mailin; Shin, Youngah; Chin, Donovan N.; Keller, Caroline Gubser; Beibel, Martin; Renaud, Nicole A.; Smith, Thomas M.; Salcius, Michael; Shi, Xiaoying; Hild, Marc; Servais, Rebecca; Jain, Monish; Deng, Lin; Bullock, Caroline; McLellan, Michael; Schuierer, Sven; Murphy, Leo; Blommers, Marcel J. J.; Blaustein, Cecile; Berenshteyn, Frada; Lacoste, Arnaud; Thomas, Jason R.; Roma, Guglielmo; Michaud, Gregory A.; Tseng, Brian S.; Porter, Jeffery A.; Myer, Vic E.; Tallarico, John A.; Hamann, Lawrence G.; Curtis, Daniel; Fishman, Mark C.; Dietrich, William F.; Dales, Natalie A.; Sivasankaran, Rajeev
SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice (vol 11, pg 511, 2015)
NATURE CHEMICAL BIOLOGY
IF13.7
2015-08-184
OAAI
Palacino, James; Swalley, Susanne E.; Song, Cheng; Cheung, Atwood K.; Shu, Lei; Zhang, Xiaolu; Van Hoosear, Mailin; Shin, Youngah; Chin, Donovan N.; Keller, Gubser; Beibel, Martin; Renaud, Nicole A.; Smith, Thomas M.; Salcius, Michael; Shi, Xiaoying; Hild, Marc; Servais, Rebecca; Jain, Monish; Deng, Lin; Bullock, Caroline; McLellan, Michael; Schuierer, Sven; Murphy, Leo; Blommers, Marcel J. J.; Blaustein, Cecile; Berenshteyn, Frada; Lacoste, Arnaud; Thomas, Jason R.; Roma, Guglielmo; Michaud, Gregory A.; Tseng, Brian S.; Porter, Jeffery A.; Myer, Vic E.; Tallarico, John A.; Hamann, Lawrence G.; Curtis, Daniel; Fishman, Mark C.; Dietrich, William F.; Dales, Natalie A.; Sivasankaran, Rajeev
SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice
NATURE CHEMICAL BIOLOGY
IF13.7
2015-06-01375
PREAI
Palacino, James; Swalley, Susanne E.; Song, Cheng; Cheung, Atwood K.; Shu, Lei; Zhang, Xiaolu; Van Hoosear, Mailin; Shin, Youngah; Chin, Donovan N.; Keller, Caroline Gubser; Beibel, Martin; Renaud, Nicole A.; Smith, Thomas M.; Salcius, Michael; Shi, Xiaoying; Hild, Marc; Servais, Rebecca; Jain, Monish; Deng, Lin; Bullock, Caroline; McLellan, Michael; Schuierer, Sven; Murphy, Leo; Blommers, Marcel J. J.; Blaustein, Cecile; Berenshteyn, Frada; Lacoste, Arnaud; Thomas, Jason R.; Roma, Guglielmo; Michaud, Gregory A.; Tseng, Brian S.; Porter, Jeffery A.; Myer, Vic E.; Tallarico, John A.; Hamann, Lawrence G.; Curtis, Daniel; Fishman, Mark C.; Dietrich, William F.; Dales, Natalie A.; Sivasankaran, Rajeev
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

选择性VPS34抑制剂阻断自噬并揭示NCOA4在体内铁蛋白降解和铁稳态中的作用

NATURE CELL BIOLOGY
IF19.1
2014-10-19606
PREAI
Dowdle, William E.; Nyfeler, Beat; Nagel, Jane; Elling, Robert A.; Liu, Shanming; Triantafellow, Ellen; Menon, Suchithra; Wang, Zuncai; Honda, Ayako; Pardee, Gwynn; Cantwell, John; Luu, Catherine; Cornella-Taracido, Ivan; Harrington, Edmund; Fekkes, Peter; Lei, Hong; Fang, Qing; Digan, Mary Ellen; Burdick, Debra; Powers, Andrew F.; Helliwell, Stephen B.; D'Aquin, Simon; Bastien, Julie; Wang, Henry; Wiederschain, Dmitri; Kuerth, Jenny; Bergman, Philip; Schwalb, David; Thomas, Jason; Ugwonali, Savuth; Harbinski, Fred; Tallarico, John; Wilson, Christopher J.; Myer, Vic E.; Porter, Jeffery A.; Bussiere, Dirksen E.; Finan, Peter M.; Labow, Mark A.; Mao, Xiaohong; Hamann, Lawrence G.; Manning, Brendan D.; Valdez, Reginald A.; Nicholson, Thomas; Schirle, Markus; Knapp, Mark S.; Keaney, Erin P.; Murphy, Leon O.
Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39
NATURE CHEMICAL BIOLOGY
IF13.7
2014-03-1656
PREAI
Bassilana, Frederic; Carlson, Adam; DaSilva, Jennifer A.; Grosshans, Bianka; Vidal, Solange; Beck, Valerie; Wilmeringwetter, Barbara; Llamas, Luis A.; Showalter, Todd B.; Rigollier, Pascal; Bourret, Aaron; Ramamurthy, Arun; Wu, Xu; Harbinski, Fred; Plonsky, Samantha; Lee, Lac; Ruffner, Heinz; Grandi, Paola; Schirle, Markus; Jenkins, Jeremy; Sailer, Andreas W.; Bouwmeester, Tewis; Porter, Jeffrey A.; Myer, Vic; Finan, Peter M.; Tallarico, John A.; Kelleher, Joseph F., III; Seuwen, Klaus; Jain, Rishi K.; Luchansky, Sarah J.
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2014-02-11355
OAAI
Hoffman, Gregory R.; Rahal, Rami; Buxton, Frank; Xiang, Kay; McAllister, Gregory; Frias, Elizabeth; Bagdasarian, Linda; Huber, Janina; Lindeman, Alicia; Chen, Dongshu; Romero, Rodrigo; Ramadan, Nadire; Phadke, Tanushree; Haas, Kristy; Jaskelioff, Mariela; Wilson, Boris G.; Meyer, Matthew J.; Saenz-Vash, Veronica; Zhai, Huili; Myer, Vic E.; Porter, Jeffery A.; Keen, Nicholas; McLaughlin, Margaret E.; Mickanin, Craig; Roberts, Charles W. M.; Stegmeier, Frank; Jagani, Zainab
A functional screen of the epigenome identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
MOLECULAR CANCER THERAPEUTICS
IF5.5
2013-11-010
PRE
Jagani, Zainab; Hoffman, Gregory; Rahal, Rami; Buxton, Frank; McAllister, Gregory; Xiang, Kay; Frias, Elizabeth; Huber, Janina; Lindeman, Alicia; Chen, Dongshu; Bagdasarian, Linda; Romero, Rodrigo; Ramadan, Nadire; Phadke, Tanushree; Haas, Kristy; Jaskelioff, Mariela; Wilson, Boris; Meyer, Matthew; McLaughlin, Margaret E.; Roberts, Charles W. M.; Myer, Vic; Porter, Jeff; Keen, Nicholas; Mickanin, Craig; Stegmeier, Frank

研究方向

暂未获取到该数据
C
Christopher J. Wilson
H 指数:34论文数:77被引数:1.8万
J
John A. Tallarico
H 指数:49论文数:126被引数:1.1万
L
Luis Barrera
H 指数:22论文数:47被引数:3,316
J
Jeffery A. Porter
H 指数:35论文数:60被引数:1.7万
A
Ari E. Friedland
H 指数:9论文数:24被引数:2,897
H
Hariharan Jayaram
H 指数:23论文数:64被引数:3,229
M
Markus Schirle
H 指数:52论文数:143被引数:1.9万
G
Gregory A. Michaud
H 指数:22论文数:53被引数:4,897
J
Josh Tycko
H 指数:19论文数:42被引数:2,623
M
Marc Hild
H 指数:27论文数:51被引数:1.0万