Not logged in Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors Torrente, Esther; Fodale, Valentina; Ciammaichella, Alina; Ferrigno, Federica; Ontoria, Jesus M.; Ponzi, Simona; Rossetti, Ilaria; Sferrazza, Alessio; Amaudrut, Jerome; Missineo, Antonino; Esposito, Simone; Palombo, Simone; Nibbio, Martina; Cerretani, Mauro; Bisbocci, Monica; Cellucci, Antonella; di Marco, Annalise; Alli, Cristina; Pucci, Vincenzo; Toniatti, Carlo; Petrocchi, Alessia Share Save
SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease Colarusso, Stefania; Ferrigno, Federica; Ponzi, Simona; Pavone, Francesca; Conte, Immacolata; Abate, Luigi; Beghetto, Elisa; Missineo, Antonino; Amaudrut, Jerome; Bresciani, Alberto; Paonessa, Giacomo; Tomei, Licia; Montalbetti, Christian; Bianchi, Elisabetta; Toniatti, Carlo; Ontoria, Jesus M. M. Share Save
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction Ontoria, Jesus M.; Biancofiore, Ilaria; Fezzardi, Paola; Ferrigno, Federica; Torrente, Esther; Colarusso, Stefania; Bianchi, Elisabetta; Andreini, Matteo; Patsilinakos, Alexandros; Kempf, Georg; Augustin, Martin; Steinbacher, Stefan; Summa, Vincenzo; Pacifici, Robert; Munoz-Sanjuan, Ignacio; Park, Larry; Bresciani, Alberto; Dominguez, Celia; Sherman, Leticia Toledo; Harper, Steven Share Save
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides Bresciani, Alberto; Ontoria, Jesus M.; Biancofiore, Ilaria; Cellucci, Antonella; Ciammaichella, Alina; Di Marco, Annalise; Ferrigno, Federica; Francone, Alessandra; Malancona, Savina; Monteagudo, Edith; Nizi, Emanuela; Pace, Paola; Ponzi, Simona; Rossetti, Ilaria; Veneziano, Maria; Summa, Vincenzo; Harper, Steven Share Save
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs Ontoria, Jesus M.; Paonessa, Giacomo; Ponzi, Simona; Ferrigno, Federica; Nizi, Emanuela; Biancofiore, Ilaria; Malancona, Savina; Graziani, Rita; Roberts, David; Willis, Paul; Bresciani, Alberto; Gennari, Nadia; Cecchetti, Ottavia; Monteagudo, Edith; Orsale, Maria V.; Veneziano, Maria; Di Marco, Annalise; Cellucci, Antonella; Laufer, Ralph; Altamura, Sergio; Summa, Vincenzo; Harper, Steven Share Save
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates Malancona, Savina; Donghi, Monica; Ferrara, Marco; Hernando, Jose I. Martin; Pompei, Marco; Pesci, Silvia; Ontoria, Jesus M.; Koch, Uwe; Rowley, Michael; Summa, Vincenzo Share Save
Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and-2 Mutant Tumors Jones, Philip; Altamura, Sergio; Boueres, Julia; Ferrigno, Federica; Fonsi, Massimiliano; Giomini, Claudia; Lamartina, Stefania; Monteagudo, Edith; Ontoria, Jesus M.; Orsale, Maria Vittoria; Palumbi, Maria Cecilia; Pesci, Silvia; Roscilli, Giuseppe; Scarpelli, Rita; Schultz-Fademrecht, Carsten; Toniatti, Carlo; Rowley, Michael Share Save
Identification of Novel, Selective, and Stable Inhibitors of Class II Histone Deacetylases. Validation Studies of the Inhibition of the Enzymatic Activity of HDAC4 by Small Molecules as a Novel Approach for Cancer Therapy Ontoria, Jesus M.; Altamura, Sergio; Di Marco, Annalise; Ferrigno, Federica; Laufer, Ralph; Muraglia, Ester; Palumbi, Maria Cecilia; Rowley, Michael; Scarpelli, Rita; Schultz-Fademrecht, Carsten; Scrafini, Sergio; Steinkuehler, Christian; Jones, Philip Share Save
Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase Hernando, Jose Ignacio Martin; Ontoria, Jesus Maria; Malancona, Savina; Attenni, Barbara; Fiore, Fabrizio; Bonelli, Fabio; Koch, Uwe; Di Marco, Stefania; Colarusso, Stefania; Ponzi, Simona; Gennari, Nadia; Vignetti, Sue Ellen; Ferreira, Maria del Rosario Rico; Habermann, Joerg; Rowley, Michael; Narjes, Frank Share Save
Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors Ontoria, Jesus M.; Rydberg, Edwin H.; Di Marco, Stefania; Tomei, Licia; Attenni, Barbara; Malancona, Savina; Hernando, Jose I. Martin; Gennari, Nadia; Koch, Uwe; Narjes, Frank; Rowley, Michael; Summa, Vincenzo; Carroll, Steve S.; Olsen, David B.; De Francesco, Raffaele; Altamura, Sergio; Migliaccio, Giovanni; Carfi, Andrea Share Save
The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease Ontoria, JM; Di Marco, S; Conte, I; Di Francesco, ME; Gardelli, C; Koch, U; Matassa, VG; Poma, M; Steinkühler, C; Volpari, C; Harper, S Share Save
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