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Direct-to-Biology Enabled Molecular Glue Discovery Hu, Maowei; Ochoada, Jason; Actis, Marisa; McGowan, Kevin; Jarusiewicz, Jamie A.; Yoshimura, Satoshi; McGrath, Logan; Neelakantan, Uma; Aggarwal, Anup; Mayasundari, Anand; Young, Sarah M.; Zhang, Meng; Yang, Lei; Li, Yong; Mercer, Shea; Babu, M. Madan; Fischer, Marcus; Young, Brandon M.; Yang, Jun J.; Nishiguchi, Gisele; Shelat, Anang A.; Blair, Daniel J. Share Save
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Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders Dernovsek, Jaka; Gorican, Tjasa; Gedgaudas, Marius; Zajec, Ziva; Urbancic, Dunja; Jug, Ana; Skok, Ziga; Sturtzel, Caterina; Distel, Martin; Grdadolnik, Simona Golic; Babu, Kesavan; Panchamatia, Ashna; Stachowski, Timothy R.; Fischer, Marcus; Ilas, Janez; Zubriene, Asta; Matulis, Daumantas; Zidar, Nace; Tomasic, Tihomir Share Save
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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines Nishiguchi, Gisele; Mascibroda, Lauren G.; Young, Sarah M.; Caine, Elizabeth A.; Abdelhamed, Sherif; Kooijman, Jeffrey J.; Miller, Darcie J.; Das, Sourav; McGowan, Kevin; Mayasundari, Anand; Shi, Zhe; Barajas, Juan M.; Hiltenbrand, Ryan; Aggarwal, Anup; Chang, Yunchao; Mishra, Vibhor; Narina, Shilpa; Thomas, Melvin; Loughran, Allister J.; Kalathur, Ravi; Yu, Kaiwen; Zhou, Suiping; Wang, Xusheng; High, Anthony A.; Peng, Junmin; Pruett-Miller, Shondra M.; Daniels, Danette L.; Urh, Marjeta; Shelat, Anang A.; Mullighan, Charles G.; Riching, Kristin M.; Zaman, Guido J. R.; Fischer, Marcus; Klco, Jeffery M.; Rankovic, Zoran Share Save
From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors Koravovic, Mladen; Mayasundari, Anand; Tasic, Gordana; Keramatnia, Fatemeh; Stachowski, Timothy R.; Cui, Huarui; Chai, Sergio C.; Jonchere, Barbara; Yang, Lei; Li, Yong; Fu, Xiang; Hiltenbrand, Ryan; Paul, Leena; Mishra, Vibhor; Klco, Jeffery M.; Roussel, Martine F.; Pomerantz, William CK.; Fischer, Marcus; Rankovic, Zoran; Savic, Vladimir Share Save
Dual inhibition of MAT2A and PRMT5 delivers synergistic anti-tumor responses in preclinical models of MTAP-deleted cancer Fischer, Marcus M.; Gerrick, Kimberline; Belmontes, Brian; Slemmons, Katherine; Freyman, Yevgeniy; Jain, Jay; Federowicz, Steve; Bishof, Isaac; Rao, Arjun A.; Fleury, Melissa; Mounir, Zineb; Lackner, Mark R.; Hughes, Paul E.; White, Mike; Neilan, Claire L. Share Save
MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations Gerrick, Kimberline Y.; Laraio, Jenny; Annen, Kelsey; Tran, Hoang; Fischer, Marcus M.; Freyman, Yevgeniy; Sharma, Geeta; Bishof, Isaac; Federowicz, Stephen; Pankajakshan, Divya; Neilan, Claire L.; Mangatt, Biju; Mazurek, Anthony; Lackner, Mark R.; White, Michael; Mounir, Zineb Share Save
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Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs Alcock, Lisa J.; Chang, Yunchao; Jarusiewicz, Jamie A.; Actis, Marisa; Nithianantham, Stanley; Mayasundari, Anand; Min, Jaeki; Maxwell, Dylan; Hunt, Jeremy; Smart, Brandon; Yang, Jun J.; Nishiguchi, Gisele; Fischer, Marcus; Mullighan, Charles G.; Rankovic, Zoran Share Save
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Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs Min, Jaeki; Mayasundari, Anand; Keramatnia, Fatemeh; Jonchere, Barbara; Yang, Seung Wook; Jarusiewicz, Jamie; Actis, Marisa; Das, Sourav; Young, Brandon; Slavish, Jake; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Yun, Mi-Kyung; Li, Zhenmei; Nithianantham, Stanley; Chai, Sergio; Chen, Taosheng; Shelat, Anang; Lee, Richard E.; Nishiguchi, Gisele; White, Stephen W.; Roussel, Martine F.; Potts, Patrick Ryan; Fischer, Marcus; Rankovic, Zoran Share Save
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