Corey R. Hopkins - Publications, H-index & Citations

Corey R. Hopkins

University of Nebraska Medical Center

44H指数

280论文数

5.8K被引数

收录论文 101

发表时间

Synthesis and Biological Characterization of 4,4-Difluoro-3-(phenoxymethyl)piperidine Scaffold as Dopamine 4 Receptor (D4R) Antagonist in vitro Tool compounds 4,4-二氟-3-(苯氧甲基)哌啶骨架的合成及其作为多巴胺4受体(D4R)拮抗剂在体外的工具化合物生物特性

ChemMedChem

IF3.4

2025-06-27

PREAI

Saeedeh Saeedi; Sumaiya Nahid; Anish K. Vadukoot; Corey R. Hopkins

Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds G蛋白门控内向整流钾通道1/2激活剂的进一步构效关系：体外工具化合物的合成与生物表征

CHEMMEDCHEM

IF3.4

2025-05-09

PREAI

Nahid, Sumaiya; Rahman, Fahad Imtiaz; Du, Yu; Spitznagel, Brittany D.; Singh, Sandeep K.; Chhonker, Yashpal S.; Murry, Daryl J.; Weaver, C. David; Hopkins, Corey R.

End-to-End Backbone Cyclization Enhances Passive Permeability of bRo5 Oligomeric Depsipeptides with Nonlinear Size Dependence

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2025-03-01

OAAI

Thorpe, Madelaine P.; Hopkins, Corey R.; Johnston, Jeffrey N.

Update on mGlu4 modulator patents: 2017 to present

EXPERT OPINION ON THERAPEUTIC PATENTS

IF4.6

2025-02-22

PREAI

Rahman, Fahad Imtiaz; Webster, Thomas M.; Hopkins, Corey R.

Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

ACS CHEMICAL NEUROSCIENCE

IF3.9

2024-12-11

OAAI

Poslunsey, Michael S.; Wood, Michael R.; Han, Changho; Stauffer, Shaun R.; Panarese, Joseph D.; Melancon, Bruce J.; Engers, Julie L.; Dickerson, Jonathan W.; Peng, Weimin; Noetzel, Meredith J.; Cho, Hyekyung P.; Rodriguez, Alice L.; Hopkins, Corey R.; Morrison, Ryan; Crouch, Rachel D.; Bridges, Thomas M.; Blobaum, Anna L.; Boutaud, Olivier; Daniels, J. Scott; Kates, Michael J.; Castelhano, Arlindo; Rook, Jerri M.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.

The backbone constitution drives passive permeability independent of side chains in depsipeptide and peptide macrocycles inspired by ent-verticilide

CHEMICAL SCIENCE

IF7.4

2024-01-01

OAAI

Thorpe, Madelaine P.; Smith, Abigail N.; Blackwell, Daniel J.; Hopkins, Corey R.; Knollmann, Bjorn C.; Akers, Wendell S.; Johnston, Jeffrey N.

Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-09-01

OAAI

Mashinson, Viktoriya; Webster, Thomas M.; Vadukoot, Anish K.; Tolentino, Kirsten T.; Simeon, Princess; Fatima, Iram; Dhawan, Punita; Hopkins, Corey R.

In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Molecule ent-Verticilide

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2023-06-01

PREAI

Blackwell, Daniel J.; Smith, Abigail N.; Do, Tri; Gochman, Aaron; Schmeckpeper, Jeffrey; Hopkins, Corey R.; Akers, Wendell S.; Johnston, Jeffrey N.; Knollmann, Bjorn C.

Identification and characterization of a first-generation inhibitor of claudin-1 to inhibit colon cancer progression and metastasis

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Fatima, Iram; Uppada, Jaya Prakash; Chhonker, Yashpal S.; Gowrikumar, Saiprasad; Barman, Susmita; Roy, Sourav; Tolentino, Kirsten T.; Palermo, Nicholas; Natarajan, Amar; Beauchamp, Daniel R.; Vecchio, Alex; Murry, Daryl J.; Singh, Amar B.; Hopkins, Corey R.; Dhawan, Punita

Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-03-01

OAAI

From dopamine 4 to sigma 1: Synthesis, SAR and biological characterization of a piperidine scaffold of a1 modulators

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-12-01

OAAI

Tolentino, Kirsten T.; Mashinson, Viktoriya; Sharma, Manish K.; Chhonker, Yashpal S.; Murry, Daryl J.; Hopkins, Corey R.

Structure-Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics N-me-与n-h-酰胺修饰对大环ent-Verticilide抗心律失常药的结构-活性关系

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2022-10-05

OAAI

Smith, Abigail N.; Thorpe, Madelaine P.; Blackwell, Daniel J.; Batiste, Suzanne M.; Hopkins, Corey R.; Schley, Nathan D.; Knollmann, Bjorn C.; Johnston, Jeffrey N.

Further Exploration of the Benzimidazole Scaffold as TRPC5 Inhibitors: Identification of 1-Alkyl-2-(pyrrolidin-1-yl)-1H-benzo[d]imidazoles as Potent and Selective Inhibitors

CHEMMEDCHEM

IF3.4

2022-05-24

OAAI

Sharma, Swagat; Pablo, Juan L.; Tolentino, Kirsten T.; Gallegos, Wacey; Hinman, Jennifer; Beninato, Madison; Asche, MacKenzie; Greka, Anna; Hopkins, Corey R.

Synthesis and Biological Characterization of a Series of 2-Sulfonamidebenzamides as Allosteric Modulators of MrgX1

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2022-04-19

OAAI

Sharma, Swagat; Peng, Qi; Vadukoot, Anish K.; Aretz, Christopher D.; Jensen, Aaron A.; Wallick, Alexander, I; Dong, Xinzhong; Hopkins, Corey R.

Characterization of VU0468554, a New Selective Inhibitor of Cardiac G Protein-Gated Inwardly Rectifying K+ Channels

MOLECULAR PHARMACOLOGY

IF3

2021-12-01

OAAI

Anderson, Allison; Vo, Baovi N.; de Velasco, Ezequiel Marron Fernandez; Hopkins, Corey R.; Weaver, C. David; Wickman, Kevin

Novel inhibitors of the renal inward rectifier potassium (Kir) channel of the mosquito vector Aedes aegypti

FUTURE MEDICINAL CHEMISTRY

IF3.4

2021-09-30

PREAI

Mashinson, Viktoriya; R Hopkins, Corey

TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models

FRONTIERS IN MEDICINE

IF3

2021-09-21

OAAI

Zhou, Yiming; Kim, Choah; Pablo, Juan Lorenzo B.; Zhang, Fan; Jung, Ji Yong; Xiao, Li; Bazua-Valenti, Silvana; Emani, Maheswarareddy; Hopkins, Corey R.; Weins, Astrid; Greka, Anna

Virtual screening and biological evaluation of PPARγ antagonists as potential anti-prostate cancer agents

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-09-01

PREAI

Almahmoud, Suliman; Elix, Catherine C.; Jones, Jeremy O.; Hopkins, Corey R.; Vennerstrom, Jonathan L.; Zhong, Haizhen A.

Discovery, synthesis and biological characterization of a series of N-(1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1H-pyrazol-5-yl)acetamide ethers as novel GIRK1/2 potassium channel activators

RSC MEDICINAL CHEMISTRY

IF3.6

2021-01-01

OAAI

Sharma, Swagat; Lesiak, Lauren; Aretz, Christopher D.; Du, Yu; Kumar, Sushil; Gautam, Nagsen; Alnouti, Yazen; Dhuria, Nikilesh, V; Chhonker, Yashpal S.; Weaver, C. David; Hopkins, Corey R.

Further SAR on the (Phenylsulfonyl)piperazine Scaffold as Inhibitors of the Aedes aegypti Kir1 (AeKir) Channel and Larvicides

CHEMMEDCHEM

IF3.4

2020-10-28

OAAI

Aretz, Christopher D.; Kharade, Sujay V.; Chronister, Keagan; Rusconi Trigueros, Renata; Martinez Rodriguez, Erick J.; Piermarini, Peter M.; Denton, Jerod S.; Hopkins, Corey R.

研究方向